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A comparison of the soluble antigen production by tissues infected with preparations of extracellular and intracellular influenza virus

Published online by Cambridge University Press:  15 May 2009

A. J. Beale
A. J. Beale
Affiliation:
Public Health Laboratory, Northampton
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1. The production of soluble antigen in the chorioallantoic membranes at 6 hr. can be used to measure the infectivity of influenza virus preparations.

2. Intracellular virus is much more infective when tested by soluble antigen production at 6 hr. than when tested by conventional methods.

3. It is suggested that intracellular virus differs from extracellular because more virus particles per cell are required to initiate infection.

The author is greatly indebted to Dr L. Hoyle for his advice and encouragement throughout this work. Mr G. Field gave valuable help with the mathematics.

Type
Research Article
Information
Journal of Hygiene , Volume 52 , Issue 2 , June 1954 , pp. 225 - 229
Copyright
Copyright © Cambridge University Press 1954

References

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