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A comparative study of susceptibility of primary monkey kidney cells, Hep 2 cells and HeLa cells to a variety of faecal viruses

Published online by Cambridge University Press:  15 May 2009

S. R. Pal ,
J. McQuillin  and
P. S. Gardner
S. R. Pal
Affiliation:
Virus and Tumour Research Section, Department of Microbiology, Royal Victoria Infirmary and King's College Medical School, Newcastle upon Tyne 1
J. McQuillin
Affiliation:
Virus and Tumour Research Section, Department of Microbiology, Royal Victoria Infirmary and King's College Medical School, Newcastle upon Tyne 1
P. S. Gardner
Affiliation:
Virus and Tumour Research Section, Department of Microbiology, Royal Victoria Infirmary and King's College Medical School, Newcastle upon Tyne 1
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A comparative study of the susceptibility of monkey kidney, Hep 2 and HeLa cells to enteroviruses and adenoviruses is made. It seems that this Hep 2 cell line is as effective as the monkey kidney cells in their susceptibility to vaccine strains of polioviruses and far better than monkey kidney cells in their susceptibility to strains of ECHO 6 and ECHO 11 from clinical material. It is as effective as, or slightly better than, HeLa cells for the isolation of adenoviruses. It also compares favourably with monkey kidney cells for the isolation of other enteroviruses.

We are most grateful to Glaxo Laboratories Ltd. for the supplies of monkey kidney cells used in this investigation.

Type
Research Article
Information
Journal of Hygiene , Volume 61 , Issue 4 , December 1963 , pp. 493 - 498
Copyright
Copyright © Cambridge University Press 1963

References

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