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The Clinical Value of the combined Khan and Wassermann Tests in the Tropics, with Special Reference to Yaws and Syphilis

Published online by Cambridge University Press:  15 May 2009

H. J. O'D. Burke-Gaffney
H. J. O'D. Burke-Gaffney
Affiliation:
(From the Medical Laboratory, Dar-es-Salaam, Tanganyika Territory.)
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1. Sera from 500 patients, mostly natives of East Africa, were tested by the Kahn and Wassermann tests, under conditions described.

2. Clinical data were available in the case of 448 specimens. The results of tests upon 230 sera from cases believed to be yaws and syphilis and 218 cases believed not to be yaws and syphilis are discussed. In 46 of the 230 cases, treatment had previously been given.

3. In interpreting results, the resolutions of the League of Nations' Conference on the Serodiagnosis of Syphilis were strictly followed.

4. In the performance of the tests recognised standard methods were used.

5. The two tests correlated exactly in 96·4 per cent. of all cases.

6. The Kahn test was the more sensitive to yaws and syphilis.

7. The Wassermann test alone gave one non-specific reaction.

8. The reagents used in the Kahn test did not deteriorate when kept for two months at room temperature.

9. It is suggested that although the use of both tests is preferable when practicable, the Kahn test alone is a reliable diagnostic measure in the tropics.

Type
Research Article
Information
Journal of Hygiene , Volume 31 , Issue 2 , April 1931 , pp. 215 - 224
Copyright
Copyright © Cambridge University Press 1931

References

REFERENCES

Bigger, J. W. (1921). The standardisation of suspensions of red blood cells for Wassermann tests. Lancet, 2, 1369.CrossRefGoogle Scholar
Bigger, J. W. (1921 a). The reliability of the Wassermann reaction as performed by different pathologists. J. Hygiene, 20, 383–9.Google Scholar
Burke-Gaffney, H. J. O'D. (1928). Tanganyika Territory. Annual Report of the Medical Laboratory, Dar-es-Salaam for the Year 1928, p. 31. H.M. Stationery Office.Google Scholar
Burke-Gaffney, H. J. O'D. (1929). Tanganyika Territory. Annual Report of the Deputy Director of Laboratory Service for the Year 1929. (In the press.)Google Scholar
Butler, G. G. (1923). Tanganyika Territory. Annual Medical and Sanitation Report for 1923; Report of the Laboratory, Dar-es-Salaam. H.M. Stationery Office.Google Scholar
Butler, G. G. (1924). Tanganyika Territory. Annual Medical and Sanitation Report for 1924.Google Scholar
Cookson, H. A. and Brown, K. S. (1930). Comparison of 1000 serums tested by the Kahn and Wassermann methods. Brit. Med. J. 1, 441.CrossRefGoogle Scholar
Davenport, K. M. (1930). The clinical value of the Kahn test. J. Amer. Med. Ass. 94, 1736–8.CrossRefGoogle Scholar
Figueira, L. and Trincao, C. (1929). Le sérodiagnostique de la syphilis par les réactions de Kahn et de Wassermann. C.R. Soc. de Biol. 1, 423–5.Google Scholar
Greval, S. D. S. (1929). The Kahn, Microkahn and Wassermann tests. A comparison in 2066 cases. Ind. J. Med. Res. 16, 1009–18.Google Scholar
Kahn, R. L. (1925). Serum Diagnosis of Syphilis by Precipitation. Baltimore: Williams and Wilkins, Co.Google Scholar
Kahn, R. L. (1928). The Kahn Test. London: Baillière, Tindall and Cox.Google Scholar
Kahn, R. L. (1929). The League of Nations/ Conference on laboratory test for syphilis. J. Amer. Med. Ass. 93, 351–3.CrossRefGoogle Scholar
Kauntze, W. H. (1926). Colony and Protectorate of Kenya. Annual Report of the Medical Research Laboratory for the Year 1926.Google Scholar
League, of Nations (1928). Health Organisation. Report of the 2nd Laboratory Conference in the Serodiagnosis of Syphilis, held at Copenhagen, May 21st–June 4th, 1928. Bull. Hyg. 5, 82–3 (reviewed).Google Scholar
McIntyre, M. C. and Gllman, R. L. (1929). A clinical comparison of the Kolmer complement fixation and the Kahn precipitation tests in syphilitic and non-syphilitic cases. J. Amer. Med. Ass. 93, 358–60.CrossRefGoogle Scholar
McLean, D. (1927). Observations on the relative value of the Wassermann and Kahn tests in cases of congenital syphilis. J. Path. and Bact. 30, 182–4. (Abstracted.)Google Scholar
Medical Research Committee (1921). Special Report Series No. 14. The Wassermann Test. H.M. Stationery Office, 1918. Reprinted 1921.Google Scholar
Pineda, E. V. and Wade, H. W. (1926). The public health value of the Kahn precipitation test, with special reference to yaws. Trop. Dis. Bull. 33, 929. (Abstracted.)Google Scholar
Wyler, E. J. (1929). The Wassermann Test: Technical details of No. 1 method, M.R.C. (modified). Medical Research Council. Special Report Series, No. 129. H.M. Stationery Office.Google Scholar