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Chlamydial antibodies in farmers in north-west England

Published online by Cambridge University Press:  15 May 2009

D. Hobson  and
P. Morgan -Capner
D. Hobson
Affiliation:
Department of Medical Microbiology, University of Liverpool, Liverpool L69 3BX
P. Morgan -Capner*
Affiliation:
Department of Virology, Preston Infirmary, Preston PR1 6PS
*
*Author for correspondence.
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Because of recent reports of abortion in farmers' wives following infection with ovine strains of Chlamydia psittaci during pregnancy, the distribution of chlamydial antibodies was studied in rural populations in north-west England, where endemic chalamydial infection with abortion in common in sheep. Immunoperoxidase assays with C. treachomatis and ovine C. psittaci showed no significant differences in either the frequency or titres of antibodies between sheep farmers and other types of farmer or non-farming adults living in the same areas. The frequency and titers of antibodies in farmers' wives were no greater than in farmers, and were unrelated to their previous obstetric history or type of farming. Overall, 62/255 (24%) of this rural population had antibody detected by C. trachomatis antigen and only 30/255 (13%) detected by C.Psittaci antigen. The possible significance of these findings is discussed. This survey does not suggest that the risk of infection with C.psittaci is especially high in people working with sheep, but the complications following infection during pregnancy deserve the specific instructions that have been given to pregnant women to avoid exposure, especially during lambing, in farming and veterinary work.

Type
Research Article
Information
Epidemiology & Infection , Volume 101 , Issue 2 , October 1988 , pp. 397 - 404
Copyright
Copyright © Cambridge University Press 1988

References

Ait-ken., I. D. (1983). Enzootic (chlamydial) abortion. In Diseases of Sheep (ed. Martion, W. B.). pp. 119–123. Oxford, England: Blackwell Scientific Publications.Google Scholar
Andrews., B. E..Major, R. & Palmer., S. R. (1981). Ornithosis in poultry workers. Lancet i. 632–634.CrossRefGoogle Scholar
Buxton, D. (1986). Potential danger to pregnant women of Chlamydial psittaci from sheep. Veterinary Record 118, 510–511.CrossRefGoogle ScholarPubMed
Caldwell., H. D. & Judd, R. C. (1982). Structural analysis of chlamydial outer membrane proteins. Infection and Immunity 38, 960–968.CrossRefGoogle Scholar
Cevrnini, R., Rumpianesi, F., Donati, M. & Sarov, I. (1983). A rapid immunoperoxidase assay for the detection of specific IgG antibodies to Chalmydia trachomatis. Journal of Clinical Pathology 36, 353–356.CrossRefGoogle Scholar
Eb, F., Orfila, J., Haider, F., Bouderlique, J. L. & Corbel, C. (1982). Intérêt et limites de la microméthode en immunofluorescence dans le diagnostic des infections respiratories a Chalamydia trachomatis du nourrisson. La Revue de Pédiatrie 18, 75–84.Google Scholar
Herring, A. J., Anderson, I. E., McClenaghan, M., Inglis, N. F., Williams, H., Matheson, B. A., West, C. P., Rodger, M. & Brettle, R. P. (1987). Restriction endonculease analysis of DNA from two isolates of Chlamydia psittaci obtained from human abortions. British Medical Journal 295, 1239.CrossRefGoogle Scholar
Johnson, F. W. A. (1984). Enteric infection in sheep associated with abortion. Irish Veterinary News (December 1984), 10–15.Google Scholar
Johnson, F. W. A. & Clarkson, M. J. (1986). Ovine abortion isolates. Antigenic variations detected by mouse infection. In Chlamydial Diseases of Ruminais (ed. Aitken, I. D.). Luxembourg, Office for Official Publications of the European Communities. CD–NA–10056–EN–C.Google Scholar
Johnson, F. W. A., Matheson, B. A., Williams, H., Laing, A. G., Jandial, V., Davidsonlamb, R., Halliday, G. J., Hobson, D., Wong, S. Y., Hadley, K. M., Moffat, M. A. J. & Postlethwaite, R. (1985). Abortion due to infection with Chlamydia psittaci in a sheep farmer's wife. British Medical Journal 290, 592–594.CrossRefGoogle Scholar
Kuo, C. C, Chen, H. H., Wang, S. P. & Grayston, J. T. (1986). Characteristics of TWAR strains, a new group of Chlamydia. In Chlamydial Infections (ed. Oriel, D., Ridgway, G., Schachter, J., Taylor–Robinson, D. & Ward, M.), pp. 322–324. Cambridge: Cambridge University Press.Google Scholar
Levy, N. T., Muñoz, A. & McCormack, W. M. (1983). Enzyme linked immunosorbent assay for the detection of antibody to Chlamydia trachomatis and Chlamydia psittaci. Journal of Laboratory & Clinical Medicine 102, 918–925.Google Scholar
McClenaghan, M., Herring, A. J. & Aitken, I. D. (1984). Comparison of Chlamydia psittaci isolates by DNA restriction endonuclease analysis. Infection and Immunity 45, 384–389.CrossRefGoogle ScholarPubMed
Nagington, J. (1984). Psittcosis/ornithosis in Cambridgeshire 1975–1983. Journal of Hygiene 92, 9–19.CrossRefGoogle Scholar
Richmond, S. J. & Caul, E. O. (1975). Fluorescent antibody studies in chlamyidal infections. Journal of Clinical Microbiology 1, 345–352.CrossRefGoogle Scholar