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Characteristics of gonococci isolated from men with urethritis in Dubai

Published online by Cambridge University Press:  15 May 2009

K. Al-Hattawi  and
C. A. Ison
K. Al-Hattawi
Affiliation:
Department of Medical Microbiology, St Mary's Hospital Medical School, Norfolk Place, Paddington, London W2 1PC
C. A. Ison*
Affiliation:
Department of Medical Microbiology, St Mary's Hospital Medical School, Norfolk Place, Paddington, London W2 1PC
*
* Author for correspondence.
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Neisseria gonorrhoeae were collected from men attending out-patient clinics in Dubai. The susceptibility to a range of therapeutic antibiotics and their auxotype and serotype was determined. The plasmid content of all penicillinase-producing strains was also analysed. Thirty-six strains of N. gonorrhoeae were isolated from specimens collected from 79 patients over a 24-day period. Of the 36 isolates, 9 (25%) were penicillinase-producing N. gonorrhoeae (PPNG) and 15 (42%) were chromosomally resistant N. gonorrhoeae (CMRNG). CMRNG exhibited higher levels of resistance to cefuroxime, chloramphenicol, tetracycline and erythromycin than PPNG. All isolates were susceptible to ceftriaxone and spectinomycin. Three (8%) isolates showed reduced susceptibility (MIC, ≥ 0·25 mg/1) to ciprofloxacin. Six isolates of PPNG carried the 4·4 MD and three the 3·2 MD penicillinase encoding plasmid. The total gonococcal population was phenotypically diverse, with 12 serovars, 6 auxotypes and 21 A/S classes. Gonorrhoea was found to be a major cause of urethritis in Dubai and the strains exhibited high levels of resistance to penicillin.

Type
Research Article
Information
Epidemiology & Infection , Volume 116 , Issue 1 , February 1996 , pp. 15 - 20
Copyright
Copyright © Cambridge University Press 1996

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