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Changes in the pattern of infection caused by Streptococcus pyogenes

Published online by Cambridge University Press:  19 October 2009

Ewa Gaworzewska  and
G. Colman
Ewa Gaworzewska
Affiliation:
Division of Hospital Infection, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT
G. Colman
Affiliation:
Division of Hospital Infection, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT
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The distribution of T-and M-protein antigens was determined in 12469 cultures of Streptococcus pyogenes sent to a reference laboratory. Of these 7232 (58%) were isolates from hospital patients, 249 (2%) from hospital staff and 4988 (40%) from the community. The survey extended from January 1980 to June 1987. During this timo the numbers of isolates of M-types 6, 49 and 81 rose then fell, being replaced by types 1, 3 and 28. The proportion of isolates of M-types 4 and 12 remained constant. Few strains were received from cases of nephritis or rheumatic fever but there has been an increase in the number of strains from serious infections and deaths. Forty-four of the 55 (80%) strains received since 1985 from fatal infections have belonged to M-type 1. All other strains, bar two, received from fatal infections in those years belonged to M-type 3. Representatives of M-type 1 were also associated with crysipelas. Types 3 and 4 predominated among the isolates from scarlet fever, types 1, 4, 12 and 49 from nephritis, types 49 and 81 from skin infections in meat workers and type 28 in cases of puerperal sepsis. The M-typability rate was 97% but new M antigens await definition among strains causing pyoderma.

Type
Research Article
Information
Epidemiology & Infection , Volume 100 , Issue 2 , April 1988 , pp. 257 - 269
Copyright
Copyright © Cambridge University Press 1988

References

REFERENCES

Anonymous (1951). Scrotypea of Streptococcus pyogenes: their relative prevalence in England, Wales and Northern Ireland, 1952–53. Monthly Bulletin of the Ministry of Health and the Public Health Laboratory Service 13, 171–174.Google Scholar
Anonymous (1957). Serotypes of Streptococcus pyogenes: their prevalence in England and Wales, 1952–1956. Monthly Bulletin of the Ministry of Health and the Public Health Laboratory Service 16, 163–172.Google Scholar
Anonymous (1986). Communicable disease statistics: 1984 statistical tables. Scries MB2 no. 11. pp. 6–7. London: Her Majesty's Stationery Office.Google Scholar
Anthony, B. F., Kaplan, E. L., Wannamaker, L. W., Briese, F. W. & Chapman, S. S. (1969). Attack rates of neute nephritis after typo 40 strcptococcal infection of the skin and of tho respiratory tract. Journal of Clinical Investigation 48, 1697–1704.CrossRefGoogle Scholar
Barnham, M. & Kerby, J. (1984). A profile of skin sepsis in meat handlers. Journal of Infection 9, 43–50.CrossRefGoogle ScholarPubMed
Bisno, A. L. (1980). The concept of rheumatogenic and nonrheumatogenic group A streptococci. In Streptococcal Diseases and the Immune Response (ed. Rend, S. E. and Zabriskic, J. B.), pp. 780–803. New York: Academic Press.Google Scholar
Cone, L. A., Woodard, D. R., Schlievert, P. M. & Tomory, G. S. (1987). Clinical and bacterilogic observations of a toxic shock-like syndrome due to Streptococcus pyogenes. New England Journal of Medicine 317, 146–149.CrossRefGoogle ScholarPubMed
Cruickshank, J. G., Hart, R. J. C., George, M. & Feest, T. G. (1981). Fatal streptococcal septicaemia. British Medical Journal 282, 1944–1945.CrossRefGoogle ScholarPubMed
Dowsett, E. G., Herson, R. N., Maxted, W. R. & Widdowson, J. P. (1976). Outbreak of idiopathic erysipelas in a psychiatric hospital. British Medical Journal 1, 500–502.CrossRefGoogle Scholar
Duben, J., Jelinkova, J., Mickova, S., Havlickova, H., Vojtechovska, H., Beranek, M. & Rotta, J. (1978). Nine-year study of streptococcal infections in a sample of the general population. Journal of Hygiene, Epidemiology, Microbiology and Immunology 22, 162–176.Google Scholar
Efstratiou, A. (1980). Preparation of Streptococcus pyogenes suspensions for typing by the agglutination method. Medical Laboratory Sciences 34, 361–363.Google Scholar
Efstratiou, A., Colman, G., Lightfoot, N. F. & Cruickshank, J. G. (1982). Streptococcal pyoderma in a military training establishment. In Basic Concepts of Streptococci and Streptococcal Diseases (ed. Holm, S. E. and Christensen, P.), pp. 23–24. Chertsey, Surrey: Reedbooks.Google Scholar
Ferrieri, P. (1975). Acute post-streptococcal glomcrulonephritis and its relationship to the epidemiology of streptococcal infections. Minnesota Medicine 581, 598–602.Google Scholar
Ferrieri, P., Dajani, A. S., Wannamaker, L. W. & Chapman, S. S. (1972). Natural history of impetigo. I. Site sequence of acquisition and familial patterns of spread of cutaneous streptococci. Journal of Clinical Investigation 51, 2851–2862.CrossRefGoogle ScholarPubMed
Fraser, C. A. M. (1982). Preparation of specific antisera to the opacity factors of group-A streptococci. Journal of Medical Microbiology 15, 153–162.CrossRefGoogle Scholar
Fraser, C. A. M., Ball, L. C.Morris, C. A. & Noah, N. D. (1977). Serological characterization of group-A streptococci associated with skin sepsis in meat handlers. Journal of Hygiene 78, 283–296.CrossRefGoogle ScholarPubMed
Fraser, C. A. M. & Colman, G. (1985). Some provisional M-types among Streptococcus pyogenes (Lanccfleld group A). In Recent Advances in Streptococci and Streplococcal Diseases (ed. Kimura, Y., Kotami, S. and Shiokawa, Y.), pp. 35–36. Bracknell, Berkshire: Rccdbooks.Google Scholar
Guirguis, N., Fraser, D. W., Facklam, R. R., El Kholy, A. & Wannamaker, L. W. (1982). Type-specific immunity and pharyngcal acquisition of group A streptococcus. American Journal of Epidemiology 116, 933–939.CrossRefGoogle ScholarPubMed
Hallas, G. (1985). The production of pyrogenic exotoxins by group A streptococci. Journal of Hygiene 95, 47–57.CrossRefGoogle ScholarPubMed
Johnston, K. H. & Zahriskie, J. B. (1986).Purification and partial characterization of the nephritis strain-associated protein from Streptococcus pyogenes, group A. Journal of Experimental Medicine 163, 697–712.CrossRefGoogle ScholarPubMed
Jorup-Rönström, C. (1986). Epidemiological, bacteriological and complicating features of erysipelas. Scandinavian Journal of Infectious Diseases 18, 519–524.CrossRefGoogle ScholarPubMed
Kaplan, E. L., Anthony, B. F., Chapman, S. S., Ayoub, E. M. & Wannamaker, L. W. (1970). The influence of the site of infection on the immune response to group A streptococci. Journal of Clinical Investigation 49, 1405–1414.CrossRefGoogle ScholarPubMed
Köhler, W. (1974). Results of the second international Streptococcus pyogenes type distribution survey. In Streptococcal Disease and the Community (ed. Haverkorn, M. J.), pp. 10–13. Amsterdam: Excerpta Medica.Google Scholar
Leppard, B. J., Seal, D. V., Colman, G. & Hallas, G. (1985). The value of bacteriology and serology in the diagnosis of ccllulitis and erysipelas. British Journal of Dermatology 112, 559–567.CrossRefGoogle ScholarPubMed
Lütticken, R., Wendorff, U., Lütticken, D. & Wannamaker, L. W. (1977). Typing of group A streptococci from an urban area (Köln) in West Germany. Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A. 237, 35–43.Google Scholar
Maxted, W. R. (1956). The indirect bactericidal test as a means of identifying antibody to the M antigen of Streptococcus pyogenes. British Journal of Experimental Pathology 37, 415–422.Google Scholar
Maxted, W. R., Widdowson, J. P., Fraser, C. A. M.Ball, L. & Bassett, D. C. J. (1974). Streptococcal typing by means of the serum opacity reaction. In Streptococcal Disease and the Community (ed. Haverkorn, M. J.), pp. 48–54. Amsterdam: Excerpta Medica.Google Scholar
Mayon-White, R. T. & Perks, E. M. (1982). Why type streptococci? The epidemiology of group A streptococci in Oxfordshire 1976–1980. Jouml of Hygiene 88, 439–452.CrossRefGoogle Scholar
Mitchell, E. S. (1962). Frequency of serotypes of Streptococcus pyogenes in different diseases. Journal of Clinical Pathology 15, 231–234.CrossRefGoogle ScholarPubMed
Morris, C. A., Fell, H. W. K., Boissard, J. M., Coe, M. J. S., Colman, G., Fraser, C. A. M., Gibson, G. L., Gilbert, R. J., Hooper, W. L., Jones, D. M., Mayon-White, R. T., Pether, J. V. S., Thomas, M. E. M., Wieneke, A. A. & Wright, A. E. (1982). Tho epidemiology and control of strcptococcal sepsis in meat handlers. Environmental Health 90, 256–258.Google Scholar
Parker, M. T. (1967). International survey of tho distribution of serotypes of Streptococcus pyogenes (group A streptococci). Bulletin of the World Health Organisation 37, 513–527.Google Scholar
Pinney, A. M. (1974). Some type-associated characteristics of group A streptococci. In Streptococcal Disease and the Community (ed. Haverkorn, M. J.), pp. 56–64. Amsterdam: Excerpta Medica.Google Scholar
Pranitis, P. A. F., Murray, R. H. & Kornfeld, J. M. (1973). Effect of phenol extraction of group A streptococcus on titer and specificity of fluorescent M-typing antisera. Journal of Infectious Diseases 127, 250–254.CrossRefGoogle ScholarPubMed
Skjold, S. A. & Wannamaker, L. W. (1976). Method for phago typing group A type 49 streptococci. Journal of Clinical Microbiology 4, 232–238.CrossRefGoogle Scholar
Skjold, S. A., Wannamaker, L. W., Johnson, D. R. & Margolis, H. S. (1983). Typo 49 Streptococcus pyogenes: phago subtypes as epidemiological markers in isolates from skin sepsis and acute glomcrulonophritis. Journal of Hygiene 91, 71–76.CrossRefGoogle Scholar
Top, F. H. Jr & Wannamaker, L. W. (1968). The scrum opacity reaction of Streptococcus pyogenes: frequency of production of streptococcal lipoprotcinase by strains of different serologicul types and the relationship to M protein production. Journal of Hygiene 66, 49–58.CrossRefGoogle Scholar
Veasy, L. G., Wiedmeier, S. E., Orsmond, G. S., Ruttenberg, H. D., Boucek, M. M., Roth, S. J., Tait, V. F., Thompson, J. A., Daly, J. A., Kaplan, E. L. & Hill, H. R. (1987). Resurgence of acute rheumatic fever in tho intermountain area of tho United States. New England Journal of Medicine 316, 421–427.CrossRefGoogle Scholar
Wannamaker, L. W. (1983). Streptococcal toxins. Reviews of Infectious Diseases 5, S723–S732.CrossRefGoogle ScholarPubMed
Williams, R. E. O. (1958). Laboratory diagnosis of streptococcal infections. Bulletin of the World Health Organisation 19, 153–176.Google ScholarPubMed
Williams, R. E. O. & Maxted, W. R. (1953). The type classification of Streptococcus pyogenes. Alli Del vi Congresso Inlernazionale di Microbiologia Roma 1, 46–49.Google Scholar