Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-22T16:53:59.617Z Has data issue: false hasContentIssue false

Bacteriological monitoring in penicillin treatment of streptococcal sore throat

Published online by Cambridge University Press:  15 May 2009

P. W. Ross
Affiliation:
Department of Bacteriology, The Medical School, University of Edinburgh
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Bacteriological monitoring of penicillin therapy in 30 children with streptococcal sore throats was performed by means of salivary and throat-swab culture, on the first, third, fifth and ninth days after therapy had started. Counts of beta-haemolytic streptococci per ml. of saliva were also performed.

Results showed that salivary culture and estimation of the numbers of beta-haemolytic streptococci in the saliva were much more sensitive indices of the effectiveness of penicillin treatment than throat-swab culture.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1971

References

REFERENCES

Bartlett, D. I. & Hughes, M. H. (1969). Bacteriological swabs. British Medical Journal ii, 450.Google Scholar
Breese, B. B. & Disney, F. A. (1958). Penicillin in the treatment of streptococcal infections: a comparison of the effectiveness of five different oral and one parenteral form. New England Journal of Medicine 259, 57.Google Scholar
British National Formulary (1966). Aylesbury: Hazell, Watson and Viney Ltd.Google Scholar
Brumfitt, W. & Slater, J. D. H. (1957). Treatment of acute sore throat with penicillin: a controlled trial in young soldiers. Lancet i, 8.Google Scholar
Cruickshank, R. (1953). Clinical pathology in general practice: taking swabs. British Medical Journal ii, 1095.Google Scholar
Denny, F. W. (1957). Current Therapy. W. B. Saunders Company.Google Scholar
Denny, F. W., Wannamaker, L. W. & Hahn, E. O. (1953). Comparative effect of penicillin, aureomycin and terramycin on streptococcal tonsillitis and pharyngitis. Pediatrics 11, 7.Google Scholar
Goerner, J. R., Massell, B. F. & Jones, T. D. (1947). The use of penicillin in the treatment of carriers of beta-haemolytic streptococci among patients with rheumatic fever. New England Journal of Medicine 237, 576.Google Scholar
Hamburger, M. & Lemon, H. M. (1946). The problem of the ‘dangerous carrier’ of hemolytic streptococci: chemotherapeutic control of nasal carriers. Journal of the American Medical Association 130, 836.Google Scholar
Mitchell, R. G. & Baber, K. G. (1965). Infections by tetracycline-resistant haemolytic streptococci. Lancet i, 25.Google Scholar
Monthly Index of Medical Specialities (1968). London: Haymarket Press Ltd.Google Scholar
Parker, M. T., Maxted, W. R. & Fraser, C. A. M. (1962). Tetracycline-resistant haemolytic streptococci. British Medical Journal i, 1550.Google Scholar
Ross, P. W. (1970). M.D. thesis, University of Aberdeen.Google Scholar
Ross, P. W. (1971). Beta-haemolytic streptococci in saliva. Journal of Hygiene 69, 47.Google Scholar
Rubbo, S. D. & Benjamin, M. (1951). Some observations on survival of pathogenic bacteria on cotton wool swabs. British Medical Journal i, 983.Google Scholar
Stillerman, M., Bernstein, S. H., Smith, M. L., Gittelson, S. B. & Karelitz, S. (1960). Antibiotics in treatment of beta-haemolytic streptococcal pharyngitis. Pediatrics 25, 27.Google Scholar
Wannamaker, L. W., Denny, F. W., Perry, W. D., Rammelkamp, C. H., Ekhardt, G. C., Houser, H. B. & Hahn, E. O. (1953). The effect of penicillin prophylaxis on. streptococcal disease rates and the carrier state. New England Journal of Medicine 249, 1.Google Scholar