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Assessment of varicella underreporting in Italy

Published online by Cambridge University Press:  18 July 2002

M. L. CIOFI DEGLI ATTI
Affiliation:
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy
M. C. ROTA
Affiliation:
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy
D. MANDOLINI
Affiliation:
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy
A. BELLA
Affiliation:
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy
G. GABUTTI
Affiliation:
Department of Biological and Environmental Sciences and Technologies, Faculty of Science, University of Lecce, Italy
P. CROVARI
Affiliation:
Department of Health Sciences, Hygiene and Preventive Medicine Section, University of Genoa, Italy
S. SALMASO
Affiliation:
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy
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Abstract

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We conducted a study to assess the degree of varicella underreporting in Italy, and its distribution by age group and geographical area. Underreporting in individuals from 6 months to 20 years of age was computed as the ratio between the varicella seroprevalence in 1996 and the 1996 lifetime cumulative incidence based on statutory notifications. The degree of underreporting at the national level was 7·7 (95% CI 7·4–7·9); underreporting was greater in older age groups and in southern Italy. Quantification of underreporting can contribute to better understanding of the burden of varicella and to evaluating the potential impact of mass vaccination.

Type
Research Article
Copyright
2002 Cambridge University Press