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Antibody to streptococcal opacity factor in human sera

Published online by Cambridge University Press:  15 May 2009

W. R. Maxted ,
Jean P. Widdowson  and
Cherry A. M. Fraser
W. R. Maxted
Affiliation:
Cross-Infection Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, NW9 5HT
Jean P. Widdowson
Affiliation:
Cross-Infection Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, NW9 5HT
Cherry A. M. Fraser
Affiliation:
Cross-Infection Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, NW9 5HT
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Summary

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Two tests are described for detecting antibody to the type-specific opacity factor (OF) of group A streptococci. This antibody was detected among patients convalescent from streptococcal sore throat in two communities in which out-breaks due to opacity factor-producing strains of group A streptococci occurred.

In an outbreak due to streptococci of M-type 22 there was a close correspondence between the distribution of anti-OF and of bactericidal M-antibody for the type. In a smaller outbreak due to M-type 58 streptococci, however, M-antibody was detected more often than antibody of OF.

Type
Research Article
Information
Journal of Hygiene , Volume 71 , Issue 1 , March 1973 , pp. 35 - 42
Copyright
Copyright © Cambridge University Press 1973

References

REFERENCES

Gooder, H. (1961). Association of a serum opacity reaction with serological type in Streptococcus pyogenes. Journal of General Microbiology 25, 347–52.CrossRefGoogle ScholarPubMed
Krumweide, E. (1954). Studies on a lipoproteinase of group A streptococci. Journal of Experimental Medicine 100, 629–39.CrossRefGoogle Scholar
Lancefield, Rebecca C. (1959). Persistence of type-specific antibodies in man following infection with group A streptococci. Journal of Experimental Medicine 110, 271–92.CrossRefGoogle ScholarPubMed
Maxted, W. R., Widdowson, Jean P., Fraser, Cherry M., Ball, Ly. C. & Bassett, D. C. J. (1973). The use of the serum opacity reaction in the typing of group A streptococci. Journal of Medical Microbiology (to be published).CrossRefGoogle Scholar
Top, F. H. Jr, & Wannamaker, L. W. (1968). The serum opacity reaction of Streptococcus pyogenes. The demonstration of multiple strain-specific lipoproteinase antigen. Journal of Experimental Medicine 127, 1013–34.CrossRefGoogle Scholar
Wannamaker, L. W. (1970). Differences between streptococcal infections of the throat and of the skin. New England Journal of Medicine 282, 23–31.CrossRefGoogle ScholarPubMed
Ward, H. K. & Rudd, G. V. (1938). Studies on haemolytic streptococci from human sources. 1. The cultural characteristics of potentially virulent strains. Australian Journal of Experimental Biology & Medical Science 16, 181–92.CrossRefGoogle Scholar
Widdowson, Jean P., Maxted, W. R. & Grant, Doris L. (1970). The production of opacity in serum by group A streptococci and its relationship with the presence of M antigen. Journal of General Microbiology 61, 343–53.CrossRefGoogle Scholar
Widdowson, Jean P., Maxted, W. R., Grant, Doris L. & Pinney, Alison M. (1971). The relationship between M-antigen and opacity factor in group A streptococci. Journal of General Microbiology 65, 69–80.CrossRefGoogle ScholarPubMed
Williams, R. E. O. (1958). Laboratory diagnosis of streptococcal infection. Bulletion of the World Health Organization 19, 153–76.Google Scholar