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The antibacterial activity of chloroxylenol in combination with ethylenediaminetetra-acetic acid

Published online by Cambridge University Press:  15 May 2009

J. Dankert  and
I. K. Schut
J. Dankert
Affiliation:
Laboratory of Medical Microbiology and Hospital Epidemiology, University of Groningen, Groningen, The Netherlands
I. K. Schut
Affiliation:
Laboratory of Medical Microbiology and Hospital Epidemiology, University of Groningen, Groningen, The Netherlands
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The bactericidal activity of RBA 777 has been found to vary with both the cultural and environmental test conditions against Pseudomonas aeruginosa and to a lesser extent against Staphylococcus aureus. These variations may explain certain anomalies in earlier work regarding the activity of chloroxylenol-based products. The addition of EDTA to RBA 777 has brought about an improvement in the performance against P. aeruginosa and this activity is confirmed in vivo. Previous reports have already illustrated this potential and the evaluations of the new antibacterial agent DA 136 confirms and extends these results to its performance under adverse conditions, often associated with the hospital environment.

Type
Research Article
Information
Journal of Hygiene , Volume 76 , Issue 1 , February 1976 , pp. 11 - 22
Copyright
Copyright © Cambridge University Press 1976

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