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An interference phenomenon caused by Pasteurella pestis

Published online by Cambridge University Press:  15 May 2009

W. R. Parry
W. R. Parry
Affiliation:
From the Microbiological Research Department, Porton, near Salisbury, Wilts.
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An interference phenomenon was produced by the intraperitoneal injection of broth culture dilutions of Pasteurella pestis grown at 28° C. into small white rats.

At a critical level of approximately 106Past. pestis L37 marked interference was produced. Doses of 104 or 107 killed rats readily.

Interference was produced by the addition of killed organisms, a cell-free vaccine or a live vaccine, to small lethal doses of L37.

Non-specific interference was produced by the intravenous injection of Indian ink prior to the intraperitoneal challenge with Past. pestis L37.

Type
Research Article
Information
Journal of Hygiene , Volume 54 , Issue 2 , June 1956 , pp. 227 - 233
Copyright
Copyright © Cambridge University Press 1956

References

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