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An antigenic variant of the Hong Kong/68 influenza A 2 virus

Published online by Cambridge University Press:  15 May 2009

Marguerite S. Pereira  and
G. C. Schild
Marguerite S. Pereira
Affiliation:
Virus Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, London, NW 9 5HT
G. C. Schild
Affiliation:
World Influenza Centre, National Institute for Medical Research, Mill Hill, London, N.W. 7
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Summary

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Both the haemagglutinin and the neuraminidase of influenza A 2 virus have undergone progressive antigenic drift since this subtype first appeared in 1957.

In 1968 a strain showing a much greater antigenic difference was isolated in Hong Kong. This variant has been responsible for epidemics throughout the world in the past 2 years.

In the second year of its prevalence a small proportion of strains isolated showed a small but definite antigenic change, related principally to the haemagglutinin component.

This new variant formed about 4 % of all strains investigated and was detected in Britain, Portugal, France and New Zealand.

Type
Research Article
Information
Journal of Hygiene , Volume 69 , Issue 1 , March 1971 , pp. 99 - 103
Copyright
Copyright © Cambridge University Press 1971

References

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