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The Agglutination of Standard Agglutinable Cultures of the Flexner-group of Dysentery Bacilli by Non-dysenteric Human Sera

Published online by Cambridge University Press:  15 May 2009

A. D. Gardner
A. D. Gardner
Affiliation:
From the Standards Laboratory (Medical Research Council), Department of pathology, University of Oxford.
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1. The results are recorded of the degrees to which standard agglutinable cultures of five serological types Flexner-group bacilli (V, W, X, Y, Z) are agglutinated by non-dysenteric human sera.

2. Certian of these cultures are more highly agglutinated by some normal human sera than was anticipated.

3. In order that the sera of non-dysenteric subjects may all (or parctically all) be found to contain less than 10 or less than 20 units in males and females respectively, the reduction-factors of agglutinability at persent in use for certain of these cultures must be somewhat increased.

4. The conception of a limit, above which no “normal” serum will be found to react, is only valid as a compromise between truth and convenience. Repetition of agglutination-tests capable of measuring the fluctuation of agglutinins in active infection is the only safe and scientific procedure.

Type
Research Article
Information
Journal of Hygiene , Volume 21 , Issue 4 , August 1923 , pp. 399 - 405
Copyright
Copyright © Cambridge University Press 1923

References

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