Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-25T00:24:06.634Z Has data issue: false hasContentIssue false
  • English
  • Français

Agglutination of red blood cells of different animal species by influenza and Newcastle disease viruses

Published online by Cambridge University Press:  15 May 2009

C. M. Chu
C. M. Chu
Affiliation:
From the Department of Bacteriology, London School of Hygiene and Tropical Medicine
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The agglutination of red cells of seventeen animal species by influenza and Newcastle disease viruses has been quantitatively investigated. The peculiar behaviour of one group of red cells, illustrated by ox, toward influenza virus heated for 30 min. at 56° C. and toward purified N.D.V. has been studied in detail. It is concluded that heated influenza virus acquires an apparently increased titre against ox cells because it has lost its eluting power. Similarly, purified N.D.V. is less readily eluted from red cells, due to the elimination of an ‘elution-hastening factor’ present in infected fluid. The present study illustrates the importance of careful adjustment of all possible variable conditions for individual viruses and individual red cell systems.

Type
Research Article
Information
Journal of Hygiene , Volume 46 , Issue 3 , September 1948 , pp. 239 - 246
Copyright
Copyright © Cambridge University Press 1948

References

REFERENCES

Beveridge, W. I. B. & Lind, P. E. (1946). Aust. J. Exp. Biol. Med. Sci. 24, 127.CrossRefGoogle Scholar
Burnet, F. M. (1947). Aust. J. Sci. 10, 21.Google Scholar
Burnet, F. M. (1948). Lancet, 254, 7.CrossRefGoogle Scholar
Burnet, F. M. & Bull, D. R. (1943). Aust. J. Exp. Biol. Med. Sci. 21, 55.CrossRefGoogle Scholar
Chu, C. M. (1948 a). Nature, Lond., 161, 606.CrossRefGoogle Scholar
Chu, C. M. (1948 b). In preparation.Google Scholar
Clark, E. & Nagler, F. P. O. (1943). Aust. J. Exp. Biol. Med. Sci. 21, 103.CrossRefGoogle Scholar
Cunha, R., Weil, M. L., Beard, D., Taylor, A. R., Sharp, D. G. & Beard, J. W. (1947). J. Immunol. 55, 69.CrossRefGoogle Scholar
Curnen, E. C. & Horsfall, F. L. Jr (1946). J. Exp. Med. 83, 105.CrossRefGoogle Scholar
Florman, A. L. (1947). Proc. Soc. Exp. Biol., N.Y., 64, 458.CrossRefGoogle Scholar
Francis, T. J. (1947). J. Exp. Med. 85, 1.CrossRefGoogle Scholar
Hirst, G. K. (1942 a). J. Exp. Med. 76, 195.CrossRefGoogle Scholar
Hirst, G. K. (1942 b). J. Exp. Med. 75, 49.CrossRefGoogle Scholar
McClelland, L. & Hare, R. (1941). Canad. Publ. Hlth. J. 32, 530.Google Scholar
Magill, T. P. & Sugg, J. Y. (1947). Proc. Soc. Exp. Biol., N.Y., 66, 89.CrossRefGoogle Scholar
Miller, G. L. & Stanley, W. M. (1944). J. Exp. Med. 79, 185.CrossRefGoogle Scholar
Salk, J. E. (1944). J. Immunol. 49, 87.CrossRefGoogle Scholar