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Bench to Bedside to Bystanders – Moving Antidotes and Management Guidelines Out of the Hospital and Into the Field

Published online by Cambridge University Press:  24 September 2018

Vikhyat S. Bebarta
Vikhyat S. Bebarta*
Affiliation:
Department of Emergency Medicine, Medical Toxicology and Pharmacology, University of Colorado School of Medicine, Aurora, CO
*
Correspondence and reprint requests to Dr Vikhyat S. Bebarta, USAF Reserve IMA, Office of the Chief Scientist, 59th Medical Wing, Joint Base San Antonio-Lackland, Texas 78233-9908 (e-mail: [email protected]).
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Abstract

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Type
Commentary
Information
Disaster Medicine and Public Health Preparedness , Volume 13 , Issue 3 , June 2019 , pp. 397 - 399
Copyright
Copyright © 2018 Society for Disaster Medicine and Public Health, Inc. 

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References

REFERENCES

1. Rosman, Y, Eisenkraft, A, Milk, N, et al. Lessons learned from the Syrian sarin attack: evaluation of a clinical syndrome through social media. Ann Intern Med. 2014;160(9):644–648.Google Scholar
2. Bebarta, VS. I treated chemical attack victims – antidotes should be made available on street corners. International Business Times; 2017. http://www.ibtimes.co.uk/i-treated-syrias-chemical-attack-victims-antidotes-should-be-made-available-street-corners-1619173. Accessed September 1, 2017.Google Scholar
3. McKay, C, Scharman, EJ. Intentional and inadvertent chemical contamination of food, water, and medication. Emerg Med Clin North Am. 2015;33(1):153–177.Google Scholar
4. Jett, DA, Yeung, DT. The CounterACT Research Network: basic mechanisms and practical applications. Proc Am Thorac Soc. 2010;7(4):254–256.Google Scholar
5. Padley, AP. Gas: the greatest terror of the Great War. Anaesth Intensive Care. 2016;44 Suppl:24–30.Google Scholar
6. Bismuth, C, Borron, SW, Baud, FJ, Barriot, P. Chemical weapons: documented use and compounds on the horizon. Toxicol Lett. 2004;149(1-3):11–18.Google Scholar
7. Watermeyer, MJ, Dippenaar, N, Simo, NCT, et al. Essential lessons in a potential sarin attack disaster plan for a resource-constrained environment. Disaster Med Public Health Prep. 2017;12:249–256.Google Scholar
8. Falzone, E, Pasquier, P, Hoffmann, C, et al. Triage in military settings. Anaesth Crit Care Pain Med. 2017;36(1):43–51.Google Scholar
9. King, AM, Aaron, CK. Organophosphate and carbamate poisoning. Emerg Med Clin North Am. 2015;33(1):133–151.Google Scholar
10. Weissman, BA, Raveh, L. Multifunctional drugs as novel antidotes for organophosphates’ poisoning. Toxicology. 2011;290(2-3):149–155.Google Scholar
11. Peter, JV, Moran, JL, Pichamuthu, K, Chacko, B. Adjuncts and alternatives to oxime therapy in organophosphate poisoning – is there evidence of benefit in human poisoning? A review. Anaesth Intensive Care. 2008;36(3):339–350.Google Scholar
12. Arendse, R, Irusen, E. An atropine and glycopyrrolate combination reduces mortality in organophosphate poisoning. Hum Exp Toxicol. 2009;28(11):715–720.Google Scholar
13. Reddy, SD, Reddy, DS. Midazolam as an anticonvulsant antidote for organophosphate intoxication – a pharmacotherapeutic appraisal. Epilepsia. 2015;56(6):813–821.Google Scholar
14. Lee, CW, McLeod, SL, Peddle, MB. First responder accuracy using SALT after brief initial training. Prehosp Disaster Med. 2015;30(5):447–451.Google Scholar
15. Silvestri, S, Field, A, Mangalat, N, et al. Comparison of START and SALT triage methodologies to reference standard definitions and to a field mass casualty simulation. Am J Disaster Med. 2017;12(1):27–33.Google Scholar
16. Lerner, EB, Cone, DC, Weinstein, ES, et al. Mass casualty triage: an evaluation of the science and refinement of a national guideline. Disaster Med Public Health Prep. 2011;5(2):129–137.Google Scholar
17. Lerner, EB, Schwartz, RB, Coule, PL, et al. Mass casualty triage: an evaluation of the data and development of a proposed national guideline. Disaster Med Public Health Prep. 2008;2 Suppl 1:S25–S34.Google Scholar
18. Worek, F, Thiermann, H. The value of novel oximes for treatment of poisoning by organophosphorus compounds. Pharmacol Ther. 2013;139(2):249–259.Google Scholar
19. Dart, RC, Goldfrank, LR, Erstad, BL, et al. Expert Consensus guidelines for stocking of antidotes in hospitals that provide emergency care. Ann Emerg Med. 2017;71:314–325.Google Scholar
20. Kotora, JG. An assessment of chemical, biological, radiologic, nuclear, and explosive preparedness among emergency department healthcare providers in an inner city emergency department. J Emerg Manag. 2015;13(5):431–446.Google Scholar
21. Risavi, BL, Salen, PN, Heller, MB, Arcona, S. A two-hour intervention using START improves prehospital triage of mass casualty incidents. Prehosp Emerg Care. 2001;5(2):197–199.Google Scholar
22. Berwick, D, Downey, A, Cornett, E (eds). A National Trauma Care System: Integrating Military and Civilian Trauma Systems to Achieve Zero Preventable Deaths After Injury. Washington (DC): National Academies Press. 2016.Google Scholar
23. Baekgaard, J, Viereck, S, Moller, T, et al. The effects of public access defibrillation on survival after out-of-hospital cardiac arrest: a systematic review of observational studies. Circulation. 2017;136:954–965.Google Scholar
24. Haider, AH, Haut, ER, Velmahos, GC. Converting bystanders to immediate responders: we need to start in high school or before. JAMA Surg. 2017;152:909–910.Google Scholar
25. Lee, J, Mahon, SB, Mukai, D, et al. The vitamin B12 analog cobinamide is an effective antidote for oral cyanide poisoning. J Med Toxicol. 2016;12(4):370–379.Google Scholar
26. Bebarta, VS, Brittain, M, Chan, A, et al. Sodium nitrite and sodium thiosulfate are effective against acute cyanide poisoning when administered by intramuscular injection. Ann Emerg Med. 2017;69(6):718–725 e4.Google Scholar
27. Jett, DA. The NIH Countermeasures Against Chemical Threats Program: overview and special challenges. Ann N Y Acad Sci. 2016;1374(1):5–9.Google Scholar
28. Larsen, JC, Disbrow, GL. Project BioShield and the Biomedical Advanced Research Development Authority: a ten year progress report on meeting U.S. preparedness objectives for threat agents. Clin Infect Dis. 2017;64:1430–1434.Google Scholar