At the turn of the fifteenth and sixteenth centuries, change was fast and furious: the exploration of coastal Africa by the Portuguese, the exploration of the West Indies by the Spanish, the extermination of the island Indians, the importation of black slaves to the Iberian peninsula, then the expansion of the slave trade to the American colonies - in short, the much-heralded inauguration of European colonization overseas, with all of its attendant horrors. All of this is adequately known, it seems; the purpose of the present article is not to rehearse this history, even in summary. But if chronology has any value here, it is in making clear that, while the massacre of the Arawaks and the Caribbean Indians quickly attracted attention, eliciting protests that were to be renewed in the following centuries, the black slave trade and black slavery began somewhat discreetly, as if it took quite some time for the esprits libres in Europe to take notice of it. Over the three centuries leading up to the French revolution, blacks were transferred from their native countries to the American colonies. In Europe, these three centuries saw the development of Enlightenment thought, the revolt against domination by the Church, the call for human rights, and the will to democracy. The parallel is superficial, but troubling nevertheless: four facts appear to be linked together, and not merely chronologically: the massacre or de facto subjugation of the Indians, the trade and enslavement of blacks, and colonization. Is the last of these not the cause of and the key to understanding the other three - as well as a number of other phenomena?