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Folic acid and prevention of birth defects

Published online by Cambridge University Press:  04 July 2002

Don C Van Dyke ,
Phyllis J Stumbo ,
Mary J Berg  and
Jennifer R Niebyl
Don C Van Dyke
Affiliation:
Divisions of Developmental Disabilities and Medical Genetics, The Children's Hospital of IowaUSA.
Phyllis J Stumbo
Affiliation:
Clinical Research Center, The University of Iowa Hospitals and ClinicsUSA.
Mary J Berg
Affiliation:
College of Pharmacy, The University of IowaUSA.
Jennifer R Niebyl
Affiliation:
Department of Obstetrics and Gynecology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
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Abstract

Folate was first isolated in an unknown form in 1941. The pharmaceutical form of folate is folic acid (pteroylglutamic acid). The major source of folate in the USA is food, with primary sources being grain products, especially fortified cereals, citrus fruits, and dried beans and lentils. However, the estimation of dietary intake of folate by food tables may not reflect actual intake because naturally occurring folate in the diet may be rendered inactive by cooking and food processing.

Type
Annotation
Information
Developmental Medicine and Child Neurology , Volume 44 , Issue 6 , June 2002 , pp. 426 - 429
Copyright
© 2002 Mac Keith Press

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