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Carbamazepine hypersensitivity and the use of lymphocyte proliferation responses

Published online by Cambridge University Press:  01 April 1999

K L Brown ,
D C Henderson ,
S Nadel ,
A Tanveer  and
R Booy
K L Brown
Affiliation:
Department of Paediatrics, St Mary's Hospital Medical School, London, UK.
D C Henderson
Affiliation:
Department of Immunology, Chelsea and Westminster Hospital, London, UK.
S Nadel
Affiliation:
Department of Paediatric Intensive Care, St Mary's Hospital Medical School, London, UK.
A Tanveer
Affiliation:
Department of Paediatric Intensive Care, St Mary's Hospital Medical School, London, UK.
R Booy
Affiliation:
Department of Paediatrics, St Mary's Hospital Medical School, London, UK.
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Abstract

This report describes a case of multisystem failure in a 5-year-old boy who was being treated with carbamazepine for a seizure disorder. Carbamazepine hypersensitivity was diagnosed from the combination of the clinical constellation and the results of the patient's peripheral blood monocyte proliferation responses to both carbamazepine and a panel of other medications.

Type
Case Reports
Information
Developmental Medicine and Child Neurology , Volume 41 , Issue 4 , April 1999 , pp. 267 - 269
Copyright
© 1999 Mac Keith Press

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