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A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development

Published online by Cambridge University Press:  15 July 2011

Robert-Paul Juster ,
Gustav Bizik ,
Martin Picard ,
Genevieve Arsenault-Lapierre ,
Shireen Sindi ,
Lyane Trepanier ,
Marie-France Marin ,
Nathalie Wan ,
Zoran Sekerovic  and
Catherine Lord
...Show all authors
Robert-Paul Juster*
Affiliation:
University of Montreal McGill University
Gustav Bizik
Affiliation:
Charles University
Martin Picard
Affiliation:
McGill University
Genevieve Arsenault-Lapierre
Affiliation:
University of Montreal McGill University
Shireen Sindi
Affiliation:
University of Montreal McGill University
Lyane Trepanier
Affiliation:
University of Montreal
Marie-France Marin
Affiliation:
University of Montreal
Nathalie Wan
Affiliation:
University of Montreal
Zoran Sekerovic
Affiliation:
University of Montreal
Catherine Lord
Affiliation:
University of Montreal
Alexandra J. Fiocco
Affiliation:
Ryerson University
Pierrich Plusquellec
Affiliation:
University of Montreal University of Sherbrooke
Bruce S. McEwen
Affiliation:
Rockefeller University
Sonia J. Lupien
Affiliation:
University of Montreal
*
Address correspondence and reprint requests to: Robert-Paul Juster, 7401 Hochelaga, McGill University, Louis Riel Pavilion, Unit 226, Room RI-2678, Montreal, QC H1N 3M5, Canada; E-mail: [email protected].
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Abstract

The allostatic load (AL) model represents an interdisciplinary approach to comprehensively conceptualize and quantify chronic stress in relation to pathologies throughout the life cycle. This article first reviews the AL model, followed by interactions among early adversity, genetics, environmental toxins, as well as distinctions among sex, gender, and sex hormones as integral antecedents of AL. We next explore perspectives on severe mental illness, dementia, and caregiving as unique human models of AL that merit future investigations in the field of developmental psychopathology. A complimenting transdisciplinary perspective is applied throughout, whereby we argue that the AL model goes beyond traditional stress–disease theories toward the advancement of person-centered research and practice that promote not only physical health but also mental health.

Type
Articles
Information
Development and Psychopathology , Volume 23 , Issue 3: Allostatic Load: Part 1 , August 2011 , pp. 725 - 776
Copyright
Copyright © Cambridge University Press 2011

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