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Leveraging the developmental science of psychosocial risk to strengthen youth psychotherapy

Published online by Cambridge University Press:  15 March 2021

Rachel A. Vaughn-Coaxum  and
John R. Weisz
Rachel A. Vaughn-Coaxum*
Affiliation:
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
John R. Weisz
Affiliation:
Department of Psychology, Harvard University, Cambridge, MA, USA
*
Author for Correspondence: Rachel A. Vaughn-Coaxum, 517 Bellefield Towers, 100 N. Bellefield Ave., Pittsburgh, PA 15213, USA; E-mail: [email protected]
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Abstract

More than 50 years of randomized clinical trials for youth psychotherapies have resulted in moderate effect sizes for treatments targeting the most common mental health problems in children and adolescents (i.e., anxiety, depression, conduct problems, and attention disorders). Despite having psychotherapies that are effective for many children, there has been a dearth of progress in identifying the contextual factors that likely influence who will respond to a given psychotherapy, and under what conditions. The developmental psychopathology evidence base consistently demonstrates that psychosocial risk exposures (e.g., childhood adversities, interpersonal stressors, family dysfunction) significantly influence the onset and course of youth psychopathology. However, the developmental psychopathology framework remains to be well integrated into treatment development and psychotherapy research. We argue that advances in basic developmental psychopathology research carry promising implications for the design and content of youth psychotherapies. Research probing the effects of psychosocial risks on youth development can enrich efforts to identify contextual factors in psychotherapy effectiveness and to personalize treatment. In this article we review empirically supported and hypothesized influences of individual- and family-level risk factors on youth psychotherapy outcomes, and we propose a framework for leveraging developmental psychopathology to strengthen psychotherapies.

Keywords

childchildhood adversitypsychopathologypsychotherapy outcomesrisk factors
Type
Special Issue Article
Information
Development and Psychopathology , Volume 33 , Special Issue 2: Honoring the Legacy of Ed Zigler's Lifetime Contributions to Science, Society, and Child Wellbeing , May 2021 , pp. 670 - 683
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Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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References

Aber, J. L. III, & Zigler, E. (1981). Developmental considerations in the definition of child maltreatment. New Directions for Child and Adolescent Development, 11, 1–29.CrossRefGoogle Scholar
Arnsten, A. F., & Rubia, K. (2012). Neurobiological circuits regulating attention, cognitive control, motivation, and emotion: Disruptions in neurodevelopmental psychiatric disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 51, 356–367. doi:10.1016/j.jaac.2012.01.008CrossRefGoogle ScholarPubMed
Asarnow, J. R., Tompson, M. C., Klomhaus, A. M., Babeva, K., Langer, D. A., & Sugar, C. A. (2020). Randomized controlled trial of family-focused treatment for child depression compared to individual psychotherapy: One-year outcomes. Journal of Child Psychology and Psychiatry, 61, 662–671. doi:10.1111/jcpp.13162CrossRefGoogle ScholarPubMed
Beauchaine, T. P. (2015). Respiratory sinus arrhythmia: A transdiagnostic biomarker of emotion dysregulation and psychopathology. Current Opinion in Psychology, 3, 43–47. doi:10.1016/j.copsyc.2015.01.017CrossRefGoogle ScholarPubMed
Belsky, J. (2019). Early-life adversity accelerates child and adolescent development. Current Directions in Psychological Science, 28, 241–246. doi:10.1177/0963721419837670CrossRefGoogle Scholar
Bernard, K., Hostinar, C. E., & Dozier, M. (2015). Intervention effects on diurnal cortisol rhythms of Child Protective Services-referred infants in early childhood: preschool follow-up results of a randomized clinical trial. JAMA Pediatrics, 169, 112–119. doi:10.1001/jamapediatrics.2014.2369CrossRefGoogle ScholarPubMed
Bosch, N. M., Riese, H., Reijneveld, S. A., Bakker, M. P., Verhulst, F. C., Ormel, J., & Oldehinkel, A. J. (2012). Timing matters: Long term effects of adversities from prenatal period up to adolescence on adolescents’ cortisol stress response. The TRAILS study. Psychoneuroendocrinology, 37, 1439–1447. doi:10.1016/j.psyneuen.2012.01.013CrossRefGoogle ScholarPubMed
Bouma, E. M., Ormel, J., Verhulst, F. C., & Oldehinkel, A. J. (2008). Stressful life events and depressive problems in early adolescent boys and girls: The influence of parental depression, temperament and family environment. Journal of Affective Disorders, 105, 185–193. doi:10.1016/j.jad.2007.05.007CrossRefGoogle ScholarPubMed
Boyce, W. T., & Ellis, B. J. (2005). Biological sensitivity to context: I. An evolutionary–developmental theory of the origins and functions of stress reactivity. Development and Psychopathology, 17, 271–301. doi:10.1017/S0954579405050145CrossRefGoogle ScholarPubMed
Chorpita, B. F., & Daleiden, E. L. (2009). Mapping evidence-based treatments for children and adolescents: Application of the distillation and matching model to 615 treatments from 322 randomized trials. Journal of Consulting and Clinical Psychology, 77, 566–579.CrossRefGoogle ScholarPubMed
Cicchetti, D., & Gunnar, M. R. (2008). Integrating biological measures into the design and evaluation of preventive interventions. Development and Psychopathology, 20, 737–743. doi:10.1017/S0954579408000357CrossRefGoogle ScholarPubMed
Cicchetti, D., & Hinshaw, S. P. (2002). Editorial: Prevention and intervention science: Contributions to developmental theory. Development and Psychopathology, 14, 667–671. doi:10.1017/S0954579402004017CrossRefGoogle ScholarPubMed
Cicchetti, D., & Rogosch, F. A. (2002). A developmental psychopathology perspective on adolescence. Journal of Consulting and Clinical Psychology, 70, 6–20. doi:10.1037/0022-006X.70.1.6CrossRefGoogle ScholarPubMed
Cicchetti, D., & Rogosch, F. (1996). Equifinality and mutifinality in developmental psychopathology. Development and Psychopathology, 8, 597–600. doi:10.1017/S0954579400007318CrossRefGoogle Scholar
Cicchetti, D., & Toth, S. L. (2005). Child maltreatment. Annual Review of Clinical Psychology, 1, 409–438. doi:10.1146/annurev.clinpsy.1.102803.144029CrossRefGoogle ScholarPubMed
Coldwell, J., Pike, A., & Dunn, J. (2006). Household chaos – Links with parenting and child behaviour. Journal of Child Psychology and Psychiatry, 47, 1116–1122. doi:10.1111/j.1469-7610.2006.01655.xCrossRefGoogle ScholarPubMed
Cuijpers, P., Reijnders, M., & Huibers, M. J. H. (2019). The role of common factors in psychotherapy outcomes. Annual Review of Clinical Psychology, 15, 207–231.CrossRefGoogle ScholarPubMed
Cummings, E. M., El-Sheikh, M., Kouros, C. D., & Keller, P. S. (2007). Children's skin conductance reactivity as a mechanism of risk in the context of parental depressive symptoms. Journal of Child Psychology and Psychiatry, 48, 436–445. doi:10.1111/j.1469-7610.2006.01713.xCrossRefGoogle ScholarPubMed
Daches, S., Vine, V., Layendecker, K. M., George, C. J., & Kovacs, M. (2018). Family functioning as perceived by parents and young offspring at high and low risk for depression. Journal of Affective Disorders, 226, 355–360. doi:10.1016/j.jad.2017.09.031CrossRefGoogle Scholar
Danese, A., Moffitt, T. E., Arseneault, L., Bleiberg, B. A., Dinardo, P. B., Gandelman, S. B., … Caspi, A. (2017). The origins of cognitive deficits in victimized children: Implications for neuroscientists and clinicians. American Journal of Psychiatry, 17, 349–361. doi:10.1176/appi.ajp.2016.16030333CrossRefGoogle Scholar
Davies, P. T., Sturge-Apple, M. L., Cicchetti, D., & Cummings, E. M. (2007). The role of child adrenocortical functioning in pathways between interparental conflict and child maladjustment. Developmental Psychology, 43, 918–930. doi:10.1037/0012-1649.43.4.918CrossRefGoogle ScholarPubMed
Deater-Deckard, K., Chen, N., Wang, Z., & Bell, M. A. (2012). Socioeconomic risk moderates the link between household chaos and maternal executive function. Journal of Family Psychology, 26, 391–399. doi:10.1037/a0028331CrossRefGoogle ScholarPubMed
de Haan, A. M., Boon, A. E., de Jong, J. T. V. M., Hoeve, M., & Vermeiren, R. R. J. M. (2013). A meta-analytic review on treatment dropout in child and adolescent outpatient mental health care. Clinical Psychology Review, 33, 698–711. doi:10.1016/j.cpr.2013.04.005CrossRefGoogle ScholarPubMed
Dennison, M. J., Rosen, M. L., Sambrook, K. A., Jenness, J. L., Sheridan, M. A., & McLaughlin, K. A. (2019). Differential associations of distinct forms of childhood adversity with neurobehavioral measures of reward processing: A developmental pathway to depression. Child Development, 90, e96–e113. doi:10.1111/cdev.13011CrossRefGoogle ScholarPubMed
Dickstein, D., Finger, E. C., Brotman, M. A., Rich, B. A., Pine, D. S., Blair, J. R., & Leibenluft, E. (2010). Impaired probabilistic reversal learning in youths with mood and anxiety disorders. Psychological Medicine, 40, 1089–1100. doi:10.1017/S0033291709991462CrossRefGoogle ScholarPubMed
Doom, J. R., & Cicchetti, D. (2020). The developmental psychopathology of stress exposure in childhood. In Harkness, K. L. & Hayden, E. P. (Eds.), The Oxford handbook of stress and mental health (pp. 265–285). New York: Oxford University Press. doi:10.1093/oxfordhb/9780190681777.013.12Google Scholar
Dozier, M., Peloso, E., Lindhiem, O., Gordon, M. K., Manni, M., Sepulveda, S., … Levine, S. (2006). Developing evidence-based interventions for foster children: An example of a randomized clinical trial with infants and toddlers. Journal of Social Issues, 62, 767–785.CrossRefGoogle Scholar
Dumas, J. E., Nissley, J., Nordstrom, A., Smith, E. P., Prinz, R. J., & Levine, D. W. (2005). Home chaos: Sociodemographic, parenting, interactional, and child correlates. Journal of Clinical Child & Adolescent Psychology, 34, 93–104. doi:10.1207/s15374424jccp3401CrossRefGoogle ScholarPubMed
Duncombe, M. E., Havighurst, S. S., Holland, K. A., & Frankling, E. J. (2012). The contribution of parenting practices and parent emotion factors in children at risk for disruptive behavior disorders. Child Psychiatry & Human Development, 43, 715–733.CrossRefGoogle ScholarPubMed
Eckshtain, D., & Gaynor, S. T. (2012). Combining individual cognitive behaviour therapy and caregiver-child sessions for childhood depression: An open trial. Clinical Child Psychology and Psychiatry, 17, 266–283. doi:10.1177/1359104511404316CrossRefGoogle Scholar
Eckshtain, D., Kuppens, S., Ugueto, A., Ng, M. Y., Vaughn-Coaxum, R., Corteselli, K., & Weisz, J. R. (2020). Meta-analysis: 13-year follow-up of psychotherapy effects on youth depression. Journal of the American Academy of Child & Adolescent Psychiatry, 59, 45–63. doi:10.1016/J.JAAC.2019.04.002CrossRefGoogle ScholarPubMed
Eckshtain, D., Kuppens, S., & Weisz, J. R. (2017). Amelioration of child depression through behavioral parent training: A preliminary study. Journal of Clinical Child & Adolescent Psychology, 46, 611–618. doi:10.1080/15374416.2015.1050722CrossRefGoogle ScholarPubMed
Eckshtain, D., Marchette, L. K., Schleider, J., & Weisz, J. R. (2018). Parental depressive symptoms as a predictor of outcome in the treatment of child depression. Journal of Abnormal Child Psychology, 46, 825–837. doi:10.1007/s10802-017-0323-4CrossRefGoogle ScholarPubMed
El-Sheikh, M., Keiley, M., Erath, S., & Dyer, W. J. (2013). Marital conflict and growth in children's internalizing symptoms: The role of autonomic nervous system activity. Developmental Psychology, 49, 92–108. doi:10.1037/a0027703CrossRefGoogle ScholarPubMed
Elgar, F. J., Mills, R. S. L., McGrath, P. J., Waschbusch, D. A., & Brownridge, D. A. (2007). Maternal and paternal depressive symptoms and child maladjustment: The mediating role of parental behavior. Journal of Abnormal Child Psychology, 35, 943–955. doi:10.1007/s10802-007-9145-0CrossRefGoogle ScholarPubMed
Ellis, B. J., & Del Giudice, M. (2014). Beyond allostatic load: Rethinking the role of stress in regulating human development. Development and Psychopathology, 26, 1–20. doi:10.1017/S0954579413000849CrossRefGoogle ScholarPubMed
Evans, G. W., Gonnella, C., Marcynyszyn, L. A., Gentile, L., & Salpekar, N. (2005). The role of chaos in poverty and children's socioemotional adjustment. Psychological Science, 16, 560–565. doi:10.1111/j.0956-7976.2005.01575.xCrossRefGoogle ScholarPubMed
Evans, G. W., Li, D., & Whipple, S. S. (2013). Cumulative risk and child development. Psychological Bulletin, 139, 1342–1396. doi:10.1037/a0031808CrossRefGoogle ScholarPubMed
Feng, X., Shaw, D. S., & Silk, J. S. (2008). Developmental trajectories of anxiety symptoms among boys across early and middle childhood. Journal of Abnormal Psychology, 117, 32–47. doi:10.1037/0021-843X.117.1.32CrossRefGoogle ScholarPubMed
Feurer, C., Hammen, C. L., & Gibb, B. E. (2016). Chronic and episodic stress in children of depressed mothers. Journal of Clinical Child & Adolescent Psychology, 45, 270–278. doi:10.1080/15374416.2014.963859CrossRefGoogle ScholarPubMed
Flynn, M., & Rudolph, K. D. (2011). Stress generation and adolescent depression: Contribution of interpersonal stress responses. Journal of Abnormal Child Psychology, 39, 1187–1198. doi:10.1007/s10802-011-9527-1CrossRefGoogle ScholarPubMed
Fortenbaugh, F. C., Degutis, J., Germine, L., Wilmer, J. B., Grosso, M., Russo, K., & Esterman, M. (2015). Sustained attention across the life span in a sample of 10,000: Dissociating ability and strategy. Psychological Science, 26, 1497–1510. doi:10.1177/0956797615594896CrossRefGoogle Scholar
Francisco, R., Loios, S., & Pedro, M. (2016). Family functioning and adolescent psychological maladjustment: The mediating role of coping strategies. Child Psychiatry & Human Development, 47, 759–770. doi:10.1007/s10578-015-0609-0CrossRefGoogle ScholarPubMed
Giletta, M., Slavich, G. M., Rudolph, K. D., Hastings, P. D., Nock, M. K., & Prinstein, M. J. (2018). Peer victimization predicts heightened inflammatory reactivity to social stress in cognitively vulnerable adolescents. Journal of Child Psychology and Psychiatry, 59, 129–139. doi:10.1111/jcpp.12804CrossRefGoogle ScholarPubMed
Gilliam, W. S., & Zigler, E. F. (2000). A critical meta-analysis of all evaluations of state-funded preschool from 1977 to 1998: Implications for policy, service delivery and program evaluation. Early Childhood Research Quarterly, 15, 441–473.CrossRefGoogle Scholar
Goff, B., & Tottenham, N. (2015). Early-life adversity and adolescent depression: Mechanisms involving ventral striatum. CNS Spectrums, 20, 337–345. doi:10.1017/S1092852914000674CrossRefGoogle ScholarPubMed
Goodman, S. H., & Gotlib, I. H. (1999). Risk for psychopathology in the children of depressed mothers: A developmental model for understanding mechanisms of transmission. Psychological Review, 106(3), 458–490. doi:10.1037/0033-295x.106.3.458CrossRefGoogle ScholarPubMed
Goodman, S. H., Rouse, M. H., Connell, A. M., Broth, M. R., Hall, C. M., & Heyward, D. (2011). Maternal depression and child psychopathology: A meta-analytic review. Clinical Child and Family Psychology Review, 14, 1–27. doi:10.1007/s10567-010-0080-1CrossRefGoogle ScholarPubMed
Hamlat, E. J., Snyder, H. R., Young, J. F., & Hankin, B. L. (2019). Pubertal timing as a transdiagnostic risk for psychopathology in youth. Clinical Psychological Science, 7, 411–429. doi:10.1177/2167702618810518CrossRefGoogle ScholarPubMed
Hammen, C., Brennan, P. A., & Keenan-Miller, D. (2008). Patterns of adolescent depression to age 20: The role of maternal depression and youth interpersonal dysfunction. Journal of Abnormal Child Psychology, 36, 1189–1198. doi:10.1007/s10802-008-9241-9CrossRefGoogle ScholarPubMed
Hankin, B. L. (2015). Depression from childhood through adolescence: Risk mechanisms across multiple systems and levels of analysis. Current Opinion in Psychology, 4, 13–20. doi:10.1016/j.copsyc.2015.01.003CrossRefGoogle ScholarPubMed
Hanson, J. L., van den Bos, W., Roeber, B., Rudolph, K. D., Davidson, R., & Pollak, S. (2017). Early adversity and learning: implications for typical and atypical behavioral development. Journal of Child Psychology and Psychiatry, 58, 770–778. doi:10.1111/jcpp.12694CrossRefGoogle ScholarPubMed
Hardaway, C. R., Wilson, M. N., Shaw, D. S., & Dishion, T. J. (2012). Family functioning and externalizing behaviour among low-income children: Self-regulation as a mediator. Infant and Child Development, 21, 67–84. doi:10.1002/icdCrossRefGoogle ScholarPubMed
Harms, M. B., Shannon Bowen, K. E., Hanson, J. L., & Pollak, S. D. (2018). Instrumental learning and cognitive flexibility processes are impaired in children exposed to early life stress. Developmental Science, 21, e12596. doi:10.1111/desc.12596CrossRefGoogle ScholarPubMed
Harvey, A. G., Lee, J., Smith, R. L., Gumport, N. B., Hollon, S. D., Rabe-Hesketh, S., … Abrons, D. (2016). Improving outcome for mental disorders by enhancing memory for treatment. Behaviour Research and Therapy, 81, 35–46. doi:10.1016/J.BRAT.2016.03.007CrossRefGoogle ScholarPubMed
Harvey, A. G., Lee, J., Williams, J., Hollon, S. D., Walker, M. P., Thompson, M. A., & Smith, R. (2014). Improving outcome of psychosocial treatments by enhancing memory and learning. Perspectives on Psychological Science, 9, 161–179. doi:10.1177/1745691614521781CrossRefGoogle ScholarPubMed
Harvey, E. A., Metcalfe, L. A., Herbert, S. D., & Fanton, J. H. (2011). The role of family experiences and ADHD in the early development of oppositional defiant disorder. Journal of Consulting and Clinical Psychology, 79, 784–795. doi:10.1037/a0025672CrossRefGoogle ScholarPubMed
Heleniak, C., King, K. M., Monahan, K. C., & McLaughlin, K. A. (2018). Disruptions in emotion regulation as a mechanism linking community violence exposure to adolescent internalizing problems. Journal of Research on Adolescence, 28, 229–244. doi:10.1111/jora.12328CrossRefGoogle ScholarPubMed
Higa-McMillan, C. K., Francis, S. E., Rith-Najarian, L., & Chorpita, B. F. (2016). Evidence base update: 50 years of research on treatment for child and adolescent anxiety. Journal of Clinical Child & Adolescent Psychology, 45, 91–113.CrossRefGoogle ScholarPubMed
Hipwell, A., Keenan, K., Kasza, K., Loeber, R., Stouthamer-Loeber, M., & Bean, T. (2008). Reciprocal influences between girls’ conduct problems and depression, and parental punishment and warmth: A six year prospective analysis. Journal of Abnormal Child Psychology, 36, 663–677. doi:10.1007/s10802-007-9206-4CrossRefGoogle ScholarPubMed
Humphreys, K. L., Mehta, N., & Lee, S. S. (2012). Association of parental ADHD and depression with externalizing and internalizing dimensions of child psychopathology. Journal of Attention Disorders, 16, 267–275. doi:10.1177/1087054710387264CrossRefGoogle ScholarPubMed
Jones, P. J., Mair, P., Kuppens, S., & Weisz, J. R. (2019). An upper limit to youth psychotherapy benefit? A meta-analytic copula approach to psychotherapy outcomes. Clinical Psychological Science, 7, 1434–1449. doi:10.1177/2167702619858424CrossRefGoogle Scholar
Joormann, J., Gilbert, K., & Gotlib, I. H. (2010). Emotion identification in girls at high risk for depression. Journal of Child Psychology and Psychiatry, 51, 575–582. doi:10.1111/j.1469-7610.2009.02175.xCrossRefGoogle ScholarPubMed
Joormann, J., Talbot, L., & Gotlib, I. H. (2007). Biased processing of emotional information in girls at risk for depression. Journal of Abnormal Psychology, 116, 135–143. doi:10.1037/0021-843X.116.1.135CrossRefGoogle ScholarPubMed
Knight, A., McLellan, L., Jones, M., & Hudson, J. (2014). Pre-treatment predictors of outcome in childhood anxiety disorders: A systematic review. Psychopathology Review, 1, 77–129. doi:10.5127/pr.034613CrossRefGoogle Scholar
Lahey, B. B., Krueger, R. F., Rathouz, P. J., Waldman, I. D., & Zald, D. H. (2017). A hierarchical causal taxonomy of psychopathology across the life span. Psychological Bulletin, 143, 142–186. doi:10.1037/bul0000069CrossRefGoogle ScholarPubMed
Lambe, L. J., Craig, W. M., & Hollenstein, T. (2019). Blunted physiological stress reactivity among youth with a history of bullying and victimization: Links to depressive symptoms. Journal of Abnormal Child Psychology, 47, 1981–1993. doi:10.1007/s10802-019-00565-yCrossRefGoogle ScholarPubMed
Leijten, P., Raaijmakers, M. A. J., de Castro, B. O., & Matthys, W. (2013). Does socioeconomic status matter? A meta-analysis on parent training effectiveness for disruptive child behavior. Journal of Clinical Child & Adolescent Psychology, 42, 384–392. doi:10.1080/15374416.2013.769169CrossRefGoogle Scholar
LeMoult, J., Humphreys, K. L., Tracy, A., Hoffmeister, J.-A., Ip, E., & Gotlib, I. H. (2019). Meta-analysis: Exposure to early life stress and risk for depression in childhood and adolescence. Journal of the American Academy of Child & Adolescent Psychiatry, 59, 842–855. doi:10.1016/j.jaac.2019.10.011CrossRefGoogle ScholarPubMed
Lengua, L. J., Bush, N. R., Long, A. C., Kovacs, E. A., & Trancik, A. M. (2008). Effortful control as a moderator of the relation between contextual risk factors and growth in adjustment problems. Development and Psychopathology, 20, 509–528. doi:10.1017/S09545794080002CrossRefGoogle ScholarPubMed
Lewis, C. C., Simons, A. D., Nguyen, L. J., Murakami, J. L., Reid, M. W., Silva, S. G., & March, J. S. (2010). Impact of childhood trauma on treatment outcome in the treatment for adolescents with depression study (TADS). Journal of the American Academy of Child & Adolescent Psychiatry, 49, 132–140. doi:10.1016/J.JAAC.2009.10.007Google Scholar
Liber, J. M., Van Widenfelt, B. M., Goedhart, A. W., Utens, E. M. W. J., Van Der Leeden, A. J. M., Markus, M. T., & Treffers, P. D. A. (2008). Parenting and parental anxiety and depression as predictors of treatment outcome for childhood anxiety disorders: Has the role of fathers been underestimated? Journal of Clinical Child & Adolescent Psychology, 37, 747–758. doi:10.1080/15374410802359692CrossRefGoogle ScholarPubMed
Luby, J. L., Barch, D., Whalen, D., Tillman, R., & Belden, A. (2017). Association between early life adversity and risk for poor emotional and physical health in adolescence a putative mechanistic neurodevelopmental pathway. JAMA Pediatrics, 171, 1168–1175. doi:10.1001/jamapediatrics.2017.3009CrossRefGoogle ScholarPubMed
Maliken, A. C., & Katz, L. F. (2013). Exploring the impact of parental psychopathology and emotion regulation on evidence-based parenting interventions: A transdiagnostic approach to improving treatment effectiveness. Clinical Child and Family Psychology Review, 16, 173–186. doi:10.1007/s10567-013-0132-4CrossRefGoogle ScholarPubMed
Mars, B., Collishaw, S., Smith, D., Thapar, A., Potter, R., Sellers, R., … Thapar, A. (2012). Offspring of parents with recurrent depression: Which features of parent depression index risk for offspring psychopathology? Journal of Affective Disorders, 136, 44–53. doi:10.1016/j.jad.2011.09.002CrossRefGoogle ScholarPubMed
Masten, A. S., & Cicchetti, D. (2010). Developmental cascades. Development and Psychopathology, 22, 491–495. doi:10.1017/S0954579410000222CrossRefGoogle ScholarPubMed
Masten, A. S., Long, J. D., Kuo, S. l.-C., McCormick, C. M., & Desjardins, C. D. (2009). Developmental models of strategic intervention. European Journal of Developmental Science, 3, 282–291.Google Scholar
Maughan, A., & Cicchetti, D. (2002). Impact of child maltreatment and interadult violence on children's emotion regulation abilities and socioemotional adjustment. Child Development, 73, 1525–1542. doi:10.1111/1467-8624.00488CrossRefGoogle ScholarPubMed
McLaughlin, K. A., DeCross, S. N., Jovanovic, T., & Tottenham, N. (2019). Mechanisms linking childhood adversity with psychopathology: Learning as an intervention target. Behaviour Research and Therapy, 118, 101–109. doi:10.1016/j.brat.2019.04.008CrossRefGoogle ScholarPubMed
McLaughlin, K. A., Green, J. G., Gruber, M. J., Sampson, N. A., Zaslavsky, A. M., & Kessler, R. C. (2012). Childhood adversities and first onset of psychiatric disorders in a national sample of US adolescents. Archives of General Psychiatry, 69, 1151–1160. doi:10.1001/archgenpsychiatry.2011.2277CrossRefGoogle Scholar
McLaughlin, K. A., Hatzenbuehler, M. L., & Hilt, L. M. (2009). Emotion dysregulation as a mechanism linking peer victimization to internalizing symptoms in adolescents. Journal of Consulting and Clinical Psychology, 77, 894–904. doi:10.1037/a0015760CrossRefGoogle ScholarPubMed
McLaughlin, K. A., Rith-Narjarian, L., Dirks, M. A., & Sheridan, M. A. (2015). Low vagal tone magnifies the association between psychosocial stress exposure and internalizing psychopathology in adolescents. Journal of Clinical Child & Adolescent Psychology, 44, 314–328. doi:10.1017/CBO9781107415324.004CrossRefGoogle ScholarPubMed
McLaughlin, K. A., & Sheridan, M. A. (2016). Beyond cumulative risk. Current Directions in Psychological Science, 25, 239–245. doi:10.1177/0963721416655883CrossRefGoogle ScholarPubMed
McLaughlin, K. A., Sheridan, M. A., & Lambert, H. K. (2014). Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience. Neuroscience and Biobehavioral Reviews, 47, 578–591. doi:10.1016/j.neubiorev.2014.10.012CrossRefGoogle ScholarPubMed
Merikangas, K. R., He, J. P., Burstein, M., Swendsen, J., Avenevoli, S., Case, B., … Olfson, M. (2011). Service utilization for lifetime mental disorders in U.S. adolescents: Results of the National Comorbidity Survey–Adolescent supplement (NCS-A). Journal of the American Academy of Child & Adolescent Psychiatry, 50, 32–45. doi:10.1016/j.jaac.2010.10.006CrossRefGoogle Scholar
Merwin, S. M., Leppert, K. A., Smith, V. C., & Dougherty, L. R. (2017). Parental depression and parent and child stress physiology: Moderation by parental hostility. Developmental Psychobiology, 59, 997–1009. doi:10.1002/dev.21556CrossRefGoogle ScholarPubMed
Monti, J. D., Rudolph, K. D., & Miernicki, M. E. (2017). Rumination about social stress mediates the association between peer victimization and depressive symptoms during middle childhood. Journal of Applied Developmental Psychology, 48, 25–32. doi:10.1016/j.appdev.2016.11.003CrossRefGoogle ScholarPubMed
Moore, S. E., Norman, R. E., Suetani, S., Thomas, H. J., Sly, P. D., & Scott, J. G. (2017). Consequences of bullying victimization in childhood and adolescence: A systematic review and meta-analysis. World Journal of Psychiatry, 7, 60. doi:10.5498/wjp.v7.i1.60CrossRefGoogle ScholarPubMed
Morgan, J. K., Olino, T. M., McMakin, D. L., Ryan, N. D., & Forbes, E. E. (2013). Neural response to reward as a predictor of increases in depressive symptoms in adolescence. Neurobiology of Disease, 52, 66–74. doi:10.1016/j.nbd.2012.03.039CrossRefGoogle ScholarPubMed
Moroney, E., Tung, I., Brammer, W. A., Peris, T. S., & Lee, S. S. (2017). Externalizing outcomes of youth with and without ADHD: Time-varying prediction by parental ADHD and mediated effects. Journal of Abnormal Child Psychology, 45, 457–470. doi:10.1007/s10802-016-0215-zCrossRefGoogle ScholarPubMed
Nanni, V., Uher, R., & Danese, A. (2012). Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: A meta-analysis. American Journal of Psychiatry, 169, 141–151. doi:10.1176/appi.ajp.2011.11020335CrossRefGoogle ScholarPubMed
National Institute of Mental Health. (2015). Strategic Plan for Research. Retrieved from https://www.nimh.nih.gov/about/strategic-planning-reports/index.shtmlGoogle Scholar
National Institutes of Health. (2017). NIH Toolbox for the Assessment of Neurological and Behavioral Function. Retrieved from http://www.nihtoolbox.orgGoogle Scholar
Ng, M. Y., & Weisz, J. R. (2016). Annual research review: Building a science of personalized intervention for youth mental health. Journal of Child Psychology and Psychiatry, 57, 216–236. doi:10.1111/jcpp.12470CrossRefGoogle ScholarPubMed
O'Keeffe, S., Martin, P., Goodyer, I. M., Kelvin, R., Dubicka, B., Reynolds, S., … Fonagy, P. (2019). Prognostic implications for adolescents with depression who drop out of psychological treatment during a randomized controlled trial. Journal of the American Academy of Child & Adolescent Psychiatry, 58, 983–992. doi:10.1016/j.jaac.2018.11.019CrossRefGoogle ScholarPubMed
Olino, T. M., McMakin, D. L., Morgan, J. K., Silk, J. S., Birmaher, B., Axelson, D. A., … Forbes, E. E. (2014). Reduced reward anticipation in youth at high-risk for unipolar depression: A preliminary study. Developmental Cognitive Neuroscience, 8, 55–64. doi:10.1016/j.dcn.2013.11.005CrossRefGoogle ScholarPubMed
Ouellet-Morin, I., Odgers, C. L., Danese, A., Bowes, L., Shakoor, S., Papadopoulos, A. S., … Arseneault, L. (2011). Blunted cortisol responses to stress signal social and behavioral problems among maltreated/bullied 12-year-old children. Biological Psychiatry, 70, 1016–1023. doi:10.1016/j.biopsych.2011.06.017CrossRefGoogle ScholarPubMed
Peverill, M., McLaughlin, K. A., Finn, A. S., & Sheridan, M. A. (2016). Working memory filtering continues to develop into late adolescence. Developmental Cognitive Neuroscience, 18, 78–88. doi:10.1016/j.dcn.2016.02.004CrossRefGoogle ScholarPubMed
Pilowsky, D. J., Wickramaratne, P., Nomura, Y., & Weissman, M. M. (2006). Family discord, parental depression, and psychopathology in offspring: 20-year follow-up. Journal of the American Academy of Child & Adolescent Psychiatry, 45, 452–460. doi:10.1097/01.chi.0000198592.23078.8dCrossRefGoogle ScholarPubMed
Reising, M. M., Watson, K., Hardcastle, E., Merchant, M., Roberts, L., Forehand, R., & Compas, B. E. (2013). Parental depression and economic disadvantage: The role of parenting in associations with internalizing and externalizing symptoms in children and adolescents. Journal of Child and Family Studies, 22, 335–343. doi:10.1007/s10826-012-9582-4CrossRefGoogle ScholarPubMed
Reyno, S. M., & McGrath, P. J. (2006). Predictors of parent training efficacy for child externalizing behavior problems-A meta-analytic review. Journal of Child Psychology and Psychiatry, 47, 99–111. doi:10.1111/j.1469-7610.2005.01544.xCrossRefGoogle ScholarPubMed
Rodman, A. M., Jenness, J. L., Weissman, D. G., Pine, D. S., & McLaughlin, K. A. (2019). Neurobiological markers of resilience to depression following childhood maltreatment: The role of neural circuits supporting the cognitive control of emotion. Biological Psychiatry, 86, 464–473. doi:10.1016/j.biopsych.2019.04.033CrossRefGoogle ScholarPubMed
Rudolph, K. D. (2008). Developmental influences on interpersonal stress generation in depressed youth. Journal of Abnormal Psychology, 117, 673–679. doi:10.1037/0021-843X.117.3.673CrossRefGoogle ScholarPubMed
Schleider, J. L., Ginsburg, G. S., Keeton, C. P., Weisz, J. R., Birmaher, B., Kendall, P. C., … Walkup, J. T. (2015). Parental psychopathology and treatment outcome for anxious youth: Roles of family functioning and caregiver strain. Journal of Consulting and Clinical Psychology, 83, 213–224. doi:10.1037/a0037935CrossRefGoogle ScholarPubMed
Schleider, J. L., & Weisz, J. R. (2017). Little treatments, promising effects? Meta-analysis of single-session interventions for youth psychiatric problems. Journal of the American Academy of Child & Adolescent Psychiatry, 56, 107–115. doi:10.1016/J.JAAC.2016.11.007CrossRefGoogle ScholarPubMed
Schreier, H. M. C., Roy, L. B., Frimer, L. T., & Chen, E. (2014). Family chaos and adolescent inflammatory profiles: The moderating role of socioeconomic status. Psychosomatic Medicine, 76, 460–467. doi:10.1097/PSY.0000000000000078CrossRefGoogle ScholarPubMed
Segers, E., Beckers, T., Geurts, H., Claes, L., Danckaerts, M., & van der Oord, S. (2018). Working memory and reinforcement schedule jointly determine reinforcement learning in children: Potential implications for behavioral parent training. Frontiers in Psychology, 9, 1–11. doi:10.3389/fpsyg.2018.00394CrossRefGoogle ScholarPubMed
Shaffer, A., Lindhiem, O., & Kolko, D. J. (2013). Treatment effects of a modular intervention for early-onset child behavior problems on family contextual outcomes. Journal of Emotional and Behavioral Disorders, 21, 277–288. doi:10.1177/1063426612462742CrossRefGoogle Scholar
Shamseddeen, W., Asarnow, J. R., Clarke, G., Vitiello, B., Wagner, K. D., Birmaher, B., … Brent, D. A. (2011). Impact of physical and sexual abuse on treatment response in the Treatment of Resistant Depression in Adolescent Study (TORDIA). Journal of the American Academy of Child & Adolescent Psychiatry, 50, 293–301. doi:10.1016/j.jaac.2010.11.019CrossRefGoogle Scholar
Sheridan, M. A., McLaughlin, K. A., Winter, W., Fox, N., Zeanah, C., & Nelson, C. A. (2018). Early deprivation disruption of associative learning is a developmental pathway to depression and social problems. Nature Communications, 9, 2216. doi:10.1038/s41467-018-04381-8CrossRefGoogle ScholarPubMed
Shonkoff, J. P., Garner, A. S., Siegel, B. S., Dobbins, M. I., Earls, M. F., McGuinn, L., … The Committee on Psychosocial Aspects of Child and Family Health. (2012). The lifelong effects of early childhood adversity and toxic stress. Pediatrics, 129, e232–e246. doi:10.1542/PEDS.2011-2663CrossRefGoogle ScholarPubMed
Spies, L. A., Margolin, G., Susman, E. J., & Gordis, E. B. (2011). Adolescents’ cortisol reactivity and subjective distress in response to family conflict: The moderating role of internalizing symptoms. Journal of Adolescent Health, 49, 386–392. doi:10.1016/j.jadohealth.2011.01.014CrossRefGoogle ScholarPubMed
Sumner, J. A., Colich, N. L., Uddin, M., Armstrong, D., & McLaughlin, K. A. (2019). Early experiences of threat, but not deprivation, are associated with accelerated biological aging in children and adolescents. Biological Psychiatry, 85, 268–278. doi:10.1016/j.biopsych.2018.09.008CrossRefGoogle Scholar
Thompson, R., Mata, J., Gershon, A., & Gotlib, I. H. (2017). Adaptive coping mediates the relation between mothers’ and daughters’ depressive symptoms: A moderated mediation study. Journal of Social & Clinical Psychology, 36, 171–195. doi:10.1521/jscp.2017.36.3.171CrossRefGoogle Scholar
Tompson, M. C., Sugar, C. A., Langer, D. A., & Asarnow, J. R. (2017). A randomized clinical trial comparing family-focused treatment and individual supportive therapy for depression in childhood and early adolescence. Journal of the American Academy of Child & Adolescent Psychiatry, 56, 515–523. doi:10.1016/j.jaac.2017.03.018CrossRefGoogle ScholarPubMed
Van Loon, L. M. A., Granic, I., & Engels, R. C. M. E. (2011). The role of maternal depression on treatment outcome for children with externalizing behavior problems. Journal of Psychopathology and Behavioral Assessment, 33, 178–186. doi:10.1007/s10862-011-9228-7CrossRefGoogle ScholarPubMed
Vaughn-Coaxum, R. A., Dhawan, N., Sheridan, M. A., Hart, M. J., & Weisz, J. R. (2020). Dimensions of adversity in association with adolescents’ depression symptoms: distinct moderating roles of cognitive and autonomic function. Development and Psychopathology, 32(3), 817–830. doi:10.1017/S0954579419001172CrossRefGoogle ScholarPubMed
Vaughn-Coaxum, R. A., Wang, Y., Kiely, J., Weisz, J. R., & Dunn, E. C. (2018). Associations between trauma type, timing, and accumulation on current coping behaviors in adolescents: results from a large, population-based sample. Journal of Youth and Adolescence, 47, 842–858. doi:10.1007/s10964-017-0693-5CrossRefGoogle ScholarPubMed
Wade, M., Madigan, S., Plamondon, A., Rodrigues, M., Browne, D., & Jenkins, J. M. (2017). Developmental psychology cumulative psychosocial risk, parental socialization, and child cognitive functioning: A longitudinal cascade model. Developmental Psychology, 54, 1038–1050. doi:10.1037/dev0000493CrossRefGoogle ScholarPubMed
Wagner, S., Müller, C., Helmreich, I., Huss, M., & Tadić, A. (2015). A meta-analysis of cognitive functions in children and adolescents with major depressive disorder. European Child & Adolescent Psychiatry, 24, 5–19. doi:10.1007/s00787-014-0559-2CrossRefGoogle ScholarPubMed
Wang, M. T., & Kenny, S. (2014). Longitudinal links between fathers’ and mothers’ harsh verbal discipline and adolescents’ conduct problems and depressive symptoms. Child Development, 85, 908–923. doi:10.1111/cdev.12143CrossRefGoogle ScholarPubMed
Weisz, J. R. (2004). Psychotherapy for children and adolescents: Evidence-based treatments and case examples. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Weisz, J. R. (2015). Promoting youth self-regulation through psychotherapy: Redesigning treatments to fit complex youth in clinical care. In Oettingen, G. & Gollwitzer, P. M. (Eds.), Self-Regulation in Adolescence (The Jacobs Foundation Series on Adolescence, pp. 332–356). Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Weisz, J. R., Bearman, S. K., Ugueto, A. M., Herren, J. A., Evans, S. C., Cheron, D. M., … Jensen-Doss, A. (2020). Testing robustness of child STEPs effects with children and adolescents: A randomized controlled effectiveness trial. Journal of Clinical Child & Adolescent Psychology, 49(6), 883–896. doi:10.1080/15374416.2019.1655757CrossRefGoogle ScholarPubMed
Weisz, J. R., Kuppens, S., Ng, M. Y., Vaughn-Coaxum, R. A., Ugueto, A. M., Eckshtain, D., & Corteselli, K. A. (2019). Are psychotherapies for young people growing stronger? Tracking trends over time for youth anxiety, depression, attention-deficit/hyperactivity disorder, and conduct problems. Perspectives on Psychological Science, 14, 216–237. doi:10.1177/1745691618805436CrossRefGoogle ScholarPubMed
Wetter, E. K., & El-Sheikh, M. (2012). Trajectories of children's internalizing symptoms: The role of maternal internalizing symptoms, respiratory sinus arrhythmia and child sex. Journal of Child Psychology and Psychiatry, 53, 168–177. doi:10.1111/j.1469-7610.2011.02470.xCrossRefGoogle ScholarPubMed
Whitney, D. G., & Peterson, M. D. (2019). US national and state-level prevalence of mental health disorders and disparities of mental health care use in children. JAMA Pediatrics, 173, 389–391. doi:10.1001/jamapediatrics.2018.5399CrossRefGoogle ScholarPubMed
Yap, M. B. H., & Jorm, A. F. (2015). Parental factors associated with childhood anxiety, depression, and internalizing problems: A systematic review and meta-analysis. Journal of Affective Disorders, 175, 424–440. doi:10.1016/j.jad.2015.01.050CrossRefGoogle ScholarPubMed
Zigler, E., & Berman, W. (1983). Discerning the future of early childhood intervention. American Psychologist, 38, 894–906.CrossRefGoogle Scholar
Zigler, E., & Black, K. B. (1989). America's family support movement: Strengths and limitations. American Journal of Orthopsychiatry, 59, 6–19.CrossRefGoogle ScholarPubMed
Zigler, E., & Glick, M. (2001). A developmental approach to adult psychopathology. The Clinical Psychologist, 54, 2–11.Google Scholar
Zigler, E., & Styfco, S. J. (1994). Head Start: Criticisms in a constructive context. American Psychologist, 49, 127–132.CrossRefGoogle Scholar