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Intergenerational transmission of depression: A launch and grow model of change across adolescence

Published online by Cambridge University Press:  01 October 2010

Judy Garber  and
David A. Cole
Judy Garber*
Affiliation:
Vanderbilt University
David A. Cole
Affiliation:
Vanderbilt University
*
Address correspondence and reprint requests to: Judy Garber, Department of Psychology, 0552 Peabody, 230 Appleton Place, Vanderbilt University, Nashville, TN 37203-5721; E-mail: [email protected].
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Abstract

The present study tested a “launch-and-grow” type of cascade model in which an earlier risk factor (e.g., exposure to maternal depression by age 12) was hypothesized to predict several risk processes during development (e.g., stress, family relationships, self-worth [SW]), which then set the course for the growth of children's depressive symptoms over time. Participants were 240 mothers and children (mean age = 11.87 years, SD = 0.57) who were evaluated annually across 6 years. The Structured Clinical Interview for DSM diagnoses was used to assess mothers' psychiatric history; 185 mothers had had a mood disorder and 55 mothers were lifetime free of psychiatric diagnoses. At each assessment, mothers completed measures of their current level of depressive symptoms and stressful life events; adolescents completed measures about their perceptions of the family environment and their SW; and clinicians rated adolescents' level of depressive symptoms based on separate interviews with the adolescent and mother. Latent growth curve analyses revealed that history of maternal depression significantly predicted the intercepts of the growth trajectories of adolescents' depressive symptoms, mothers' current depressive symptoms, stressful life events, family environment, and adolescents' SW. The intercepts of each of these variables then predicted the trajectory (i.e., slope) of the growth of adolescents' depressive symptoms across the 6 years of the study. These results were consistent with the hypothesized model of maternal depression launching a set of risk factors, which in turn predict the growth of depressive symptoms during adolescence. Implications for interventions aimed at preventing depression in at-risk youth are discussed.

Type
Regular Articles
Information
Development and Psychopathology , Volume 22 , Issue 4: Developmental Cascades: Part 2 , November 2010 , pp. 819 - 830
Copyright
Copyright © Cambridge University Press 2010

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References

Abela, J. R. Z., & Hankin, B. L. (2008). Cognitive vulnerability to depression in children and adolescents: A developmental perspective. In Abela, J. R. Z. & Hankin, B. L. (Eds.), Handbook of depression in children and adolescents (pp. 35–78). New York: Guilford Press.Google Scholar
Adrian, C., & Hammen, C. L. (1993). Stress exposure and stress generation in children of depressed mothers. Journal of Consulting and Clinical Psychology, 61, 354–359.CrossRefGoogle ScholarPubMed
Anderson, C. A., & Hammen, C. L. (1993). Psychosocial outcomes of children of unipolar depressed, bipolar, medically ill, and normal women: A longitudinal study. Journal of Consulting and Clinical Psychology, 61, 448–454.CrossRefGoogle ScholarPubMed
Ashman, S. B., & Dawson, G. (2002). Maternal depression, infant psychobiological development, and risk for depression. In Goodman, S. H. & Gotlib, I. H. (Eds.), Children of depressed parents: Mechanisms of risk and implications for treatment (pp. 37–58). Washington, DC: American Psychological Association Books.CrossRefGoogle Scholar
Baron, R. M., & Kenny, D. A. (1986). The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 61, 1173–1182.CrossRefGoogle Scholar
Beardslee, W. R., Versage, E. M., & Gladstone, T. R. G. (1998). Children of affectively ill parents: A review of the past 10 years. Journal of the American Academy of Child & Adolescent Psychiatry, 37, 1134–1141.CrossRefGoogle ScholarPubMed
Brennan, P. A., Hammen, C. L., Anderson, M. J., Bor, W., Najman, J. M., & Williams, G. M. (2000). Chronicity, severity, and timing of maternal depressive symptoms: Relationships with child outcomes at age five. Developmental Psychology, 36, 759–766.CrossRefGoogle Scholar
Brennan, P. A., Le Brocque, R., & Hammen, C. (2003). Maternal depression, parent–child relationships and resilient outcomes in adolescence. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 1469–1477.CrossRefGoogle ScholarPubMed
Burt, K. B., Van Dulmen, M. H. M., Carlivati, J., Egeland, B., Sroufe, L. A., Forman, D. R., et al. (2005). Mediating links between maternal depression and offspring psychopathology: The importance of independent data. Journal of Child Psychology and Psychiatry, 46, 490–499.CrossRefGoogle ScholarPubMed
Campbell, S. B., Cohn, J., & Meyers, T. (1995). Depression in first-time mothers: Mother–infant interaction and depression chronicity. Developmental Psychology, 31, 349–357.CrossRefGoogle Scholar
Cicchetti, D., & Rogosch, F. A. (1996). Equifinality and multifinality in developmental psychopathology. Developmental Psychopathology, 8, 597–600.CrossRefGoogle Scholar
Cicchetti, D., Rogosch, F. A., & Toth, S. L. (1998). Maternal depressive disorder and contextual risk: Contributions to the development of attachment insecurity and behavior problems in toddlerhood. Developmental Psychopathology, 10, 283–300.CrossRefGoogle Scholar
Compas, B. E., Forehand, R., Keller, G., Champion, J. E., Reeslund, K. L., McKee, L., et al. (2009). Randomized clinical trial of a family cognitive–behavioral preventive intervention for children of depressed parents. Journal of Consulting and Clinical Psychology, 77, 1007–1020.CrossRefGoogle ScholarPubMed
Connell, A. M., & Goodman, S. H. (2002). The association between psychopathology in fathers versus mothers and children's internalizing and externalizing behavior problems: A meta-analysis. Psychological Bulletin, 128, 746–773.CrossRefGoogle ScholarPubMed
Davies, P. T., & Windle, M. (1997). Gender-specific pathways between maternal depressive symptoms, family discord, and adolescent adjustment. Developmental Psychology, 33, 657–668.CrossRefGoogle ScholarPubMed
DeMulder, E. K., Tarulla, L. B., Klimes-Dougan, B., & Free, K. (1995). Personality disorders of affectively ill mothers: links to maternal behavior. Journal of Personality Disorders, 9, 199–212.CrossRefGoogle Scholar
Derogatis, L. R. (1975). Brief Symptom Inventory. Baltimore, MD: Clinical Psychometric Research.Google Scholar
Derogatis, L. R. (1993). Brief symptom inventory: Administration, scoring, and procedures manual. Minneapolis, MN: National Computer Systems.Google Scholar
Derogatis, L. R., & Lazarus, L. (1994). SCL-90-R, Brief Symptom Inventory, and matching clinical rating scales. In Maruish, M. E. (Ed.), The use of psychological testing for treatment planning and outcome assessment (pp. 217–248). Hillsdale, NJ: Erlbaum.Google Scholar
Derogatis, L. R., & Melisaratos, N. (1983). The Brief Symptom Inventory: An introductory report. Psychological Medicine, 13, 595–605.CrossRefGoogle ScholarPubMed
Eamon, M. K., & Zuehl, R. M. (2001). Maternal depression and physical punishment as mediators of the effect of poverty on socioemotional problems of children in single-mother families. American Journal of Orthopsychiatry, 71, 218–226.CrossRefGoogle ScholarPubMed
England, M. J., & Sim, l. J. (Eds.). (2009). Depression in parents, parenting, and children: Opportunities to improve identification, treatment, and prevention. Washington, DC: National Academies Press.Google Scholar
Fergusson, D. M., Horwood, L. J., & Lynskey, M. T. (2005). Maternal depressive symptoms and depressive symptoms in adolescents. Journal of Child Psychology and Psychiatry, 36, 1161–1178.CrossRefGoogle Scholar
Ferrer, E., & McArdle, J. J. (2003). Alternative structural models for multivariate longitudinal data analysis. Structural Equation Modeling, 10, 493–524.CrossRefGoogle Scholar
First, M. B., Spitzer, R. L., Gibbon, M. L., & Williams, J. B. W. (1996). Structured Clinical Interview for DSM-IV Axis I Disorders—Nonpatient edition. New York: New York State Psychiatric Institute.Google Scholar
Garber, J. (2005). Depression and the family. In Hudson, J. L. & Rapee, R. M. (Eds.), Psychopathology and the Family (pp. 227–283). Oxford: Elsevier.Google Scholar
Garber, J. (2007). Depression in youth: A developmental psychopathology perspective. In Masten, A. & Sroufe, A. (Eds.), Multilevel dynamics in developmental psychopathology: Pathways to the future (Vol. 34, pp. 181–242). New York: Erlbaum.Google Scholar
Garber, J., & Robinson, N. S. (1997). Cognitive vulnerability in children at risk for depression. Cognition and Emotion, 11, 619–635.CrossRefGoogle Scholar
Ge, X., Conger, R. D., Lorenz, F. O., Shanahan, M., & Elder, G. H. (1995). Mutual influences in parents and adolescent psychological distress. Developmental Psychology, 31, 406–419.CrossRefGoogle Scholar
Goodman, S. H. (2007). Depression in mothers. Annual Review of Clinical Psychology, 3, 107–135.CrossRefGoogle ScholarPubMed
Goodman, S. H., & Gotlib, I. H. (1999). Risk for psychopathology in the children of depressed mothers: A developmental model for understanding mechanisms of transmission. Psychological Review, 106, 454–490.CrossRefGoogle ScholarPubMed
Goodman, S. H., & Tully, E. (2006). Depression in women who are mothers: An integrative model of risk for the development of psychopathology in their sons and daughters. In Keyes, C. L. M. & Goodman, S. H. (Eds.), Women and depression: A handbook for the social, behavioral, and biomedical sciences (pp. 241–280). New York: Cambridge University Press.CrossRefGoogle Scholar
Gotlib, I. H., Joormann, J., Minor, K. L., & Cooney, R. E. (2006). Cognitive and biological functioning in children at risk for depression. In Canli, T. (Ed.), Biology of personality and individual differences (pp. 353–382). New York: Guilford Press.Google Scholar
Grant, K.E., Compas, B. E., Stuhlmacher, A. F., Thurm, A. E., McMahon, S. D., Halpert, J. A. (2003). Stressors and child and adolescent psychopathology: Moving from markers to mechanisms of risk. Psychological Bulletin, 129, 447–466.CrossRefGoogle ScholarPubMed
Gunlicks, M. L., & Weissman, M. M. (2008). Change in child psychopathology with improvement in parental depression: A systematic review. Journal of the American Academy of Child & Adolescent Psychiatry, 47, 379–389.CrossRefGoogle ScholarPubMed
Hammen, C., Brennan, P. A., & Shih, J. H. (2004). Family discord and stress predictors of depression and other disorders in adolescent children of depressed and nondepressed women. Journal of the American Academy of Child & Adolescent Psychiatry, 43, 994–1002.CrossRefGoogle ScholarPubMed
Hammen, C. L. (2002). Context of stress in families of children with depressed parents. In Goodman, S. H. & Gotlib, I. H. (Eds.), Children of depressed parents: Mechanisms of risk and implications for treatment (pp. 175–202). Washington, DC: American Psychological Association.CrossRefGoogle Scholar
Hammen, C. L., Adrian, C., Gordon, D., Burge, D., Jaenicke, C., & Hiroto, D. (1987). Children of depressed mothers: Maternal strain and symptom predictors of dysfunction. Journal of Abnormal Psychology, 96, 190–198.CrossRefGoogle ScholarPubMed
Hammen, C. L., & Brennan, P. A. (2003). Severity, chronicity, and timing of maternal depression and risk for adolescent offspring diagnoses in a community sample. Archives of General Psychiatry, 60, 253–258.CrossRefGoogle Scholar
Hammen, C. L., Shih, J., Altman, T., & Brennan, P. A. (2003). Interpersonal impairment and the prediction of depressive symptoms in adolescent children of depressed and nondepressed mothers. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 571–577.CrossRefGoogle ScholarPubMed
Hammen, C. L., Shih, J. H., & Brennan, P. A. (2004). Intergenerational transmission of depression: Test of an interpersonal stress model in a community sample. Journal of Consulting and Clinical Psychology, 72, 511–522.CrossRefGoogle Scholar
Hankin, B. L., Abramson, L. Y., Moffitt, T. E., Silva, P. A., McGee, R., & Angell, K. E. (1998). Development of depression from preadolescence to young adulthood: Emerging gender differences in a 10-year longitudinal study. Journal of Abnormal Psychology, 107, 128–140.CrossRefGoogle Scholar
Harrington, R. (1996). Family-genetic findings in child and adolescent depressive disorders. International Review of Psychiatry, 8, 355–368.CrossRefGoogle Scholar
Harter, S. (1982). The perceived competence scale for children. Child Development, 53, 87–97.CrossRefGoogle Scholar
Harter, S. (1985). Self-Perception Profile for Children: Revision of the Perceived Competence Scale for Children (manual). Denver, CO: University of Denver.Google Scholar
Hoge, R. D., Andrews, D. A., Faulkner, P., & Robinson, D. (1989). The Family Relationship Index: Validity data. Journal of Clinical Psychology, 45, 897–903.3.0.CO;2-T>CrossRefGoogle ScholarPubMed
Holahan, C. J., & Moos, R. H. (1983). The quality of social support: Measures of family and work relationships. British Journal of Clinical Psychology, 22, 157–162.CrossRefGoogle Scholar
Hollingshead, A. B. (1975). Four Factor Index of Social Status. Unpublished manuscript, Yale University, Department of Sociology.Google Scholar
Jaenicke, C., Hammen, C. L., Zupan, B., Hiroto, D., Gordon, D., Adrian, C., et al. (1987). Cognitive vulnerability in children at risk for depression. Journal of Abnormal Child Psychology, 15, 559–572.CrossRefGoogle ScholarPubMed
Jaffee, S. R., & Poulton, R. (2006). Reciprocal effects of mothers' depression and children's problem behaviors from middle childhood to early adolescence. In Huston, A. C. & Ripke, M. N. (Eds.), Developmental contexts in middle childhood: Bridges to adolescence and adulthood (pp. 107–129). New York: Cambridge University Press.CrossRefGoogle Scholar
Joormann, J., Eugene, F., & Gotlib, I. H. (2009). Parental depression: Impact on offspring and mechanisms underlying transmission of risk. In Nolen-Hoeksema, S. & Hilt, L. M. (2009), Handbook of depression in adolescents (pp. 441–472). New York: Routledge/Taylor & Francis.Google Scholar
Kane, P. P., & Garber, J. (2004). The relation between fathers' depression and children's externalizing and internalizing symptoms and conflict: A meta-analysis. Clinical Psychology Review, 24, 339–360.CrossRefGoogle ScholarPubMed
Kessler, R. C., Berglund, P., Demler, O., Jin, R., & Walters, E. E. (2005). Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey replication. Archives of General Psychiatry, 62, 593–602.CrossRefGoogle ScholarPubMed
Kessler, R. C., & Walters, E. E. (1998). Epidemiology of DSM-III-R major depression and minor depression among adolescents and young adults in the National Comorbidity Survey. Depression and Anxiety, 7, 3–14.3.0.CO;2-F>CrossRefGoogle Scholar
Kraemer, H. C., Kiernan, M., Essex, M., & Kupfer, D. J. (2008). How and why criteria defining moderators and mediators differ between the Baron & Kenny and MacArthur approaches. Health Psychology, 27, 101–108.CrossRefGoogle ScholarPubMed
Lakdawalla, Z., Hankin, B. L., & Mermelstein, R. (2007). Cognitive theories of depression in children and adolescents: A conceptual and quantitative review. Clinical Child and Family Psychology Review, 10, 1–24.CrossRefGoogle ScholarPubMed
Lovejoy, M. C., Graczyk, P. A., O'Hare, E., & Neuman, G. (2000). Maternal depression and parenting behavior: A meta-analytic review. Clinical Psychology Review, 20, 561–592.CrossRefGoogle ScholarPubMed
McCubbin, H. I., & Patterson, J. M. (1987). Family Inventory of Life Events and Changes. In McCubbin, H. I. & Patterson, J. M. (Eds.), Family assessment inventories for research and practice (pp. 80–108). Madison, WI: University of Wisconsin Press.Google Scholar
Moos, R. H., & Moos, B. S. (1986). Family Environment Scale manual (rev. ed.). Palo Alto, CA: Consulting Psychological Press.Google Scholar
Murray, C. J., & Lopez, A. D. (1996). The global burden of disease. Cambridge, MA: Harvard University Press.Google ScholarPubMed
Murray, L., Woolgar, M., Cooper, P., & Hipwell, A. (2001). Cognitive vulnerability to depression in 5-year-old children of depressed mothers. Journal of Child Psychology and Psychiatry and Allied Disciplines, 42, 891–899.CrossRefGoogle ScholarPubMed
Nelson, D. R., Hammen, C., Brennan, P. A., & Ullman, J. B. (2003). The impact of maternal depression on adolescent adjustment: The role of expressed emotion. Journal of Consulting and Clinical Psychology, 71, 935–944.CrossRefGoogle ScholarPubMed
Nolen-Hoeksema, S., & Girgus, J. (1994). The emergence of gender differences in depression during adolescence. Psychological Bulletin, 115, 424–441.CrossRefGoogle ScholarPubMed
Pettit, J. W., & Joiner, T. E. (2006). Chronic depression: Interpersonal sources, therapeutic solutions. Washington, DC: American Psychological Association.CrossRefGoogle Scholar
Pine, D. S., Cohen, E., Cohen, P., & Brook, J. (1999). Adolescent depressive symptoms as predictors of adult depression: Moodiness or mood disorder? American Journal of Psychiatry, 156, 133–135.CrossRefGoogle ScholarPubMed
Poznanski, E., Mokros, H. B., Grossman, J., & Freeman, L. N. (1985). Diagnostic criteria in childhood depression. American Journal of Psychiatry, 142, 1168–1173.Google ScholarPubMed
Radke-Yarrow, M., Belmont, B., Nottelman, E., & Bottomly, L. (1990). Young children's self-conceptions: Origins in the natural discourse of depressed and normal mothers and their children. In Cicchetti, D. & Beeghly, M. (Eds.), The self in transition: Infancy to childhood (pp. 345–361). Chicago: University of Chicago Press.Google Scholar
Reinherz, H. Z., Giaconia, R. M., Hauf, A. M. C., Wasserman, M. S., & Silverman, A. B. (1999). Major depression in the transition to adulthood: Risks and impairments. Journal of Abnormal Psychology, 108, 500–510.CrossRefGoogle ScholarPubMed
Resnick, M. D., Bearman, P. S., Blum, W., Bauman, K. E., Harris, K. M., Jones, J., et al. (1997). Protecting adolescents from harm: Findings from the National Longitudinal Study on Adolescent Health. Journal of the American Medical Association, 278, 823–832.CrossRefGoogle ScholarPubMed
Rohde, P., Lewinsoh, P. M., & Seeley, J. R. (1991). Comorbidity of unipolar depression: II. Comorbidity with other mental disorders in adolescents and adults. Journal of Abnormal Psychology, 100, 214–222.CrossRefGoogle ScholarPubMed
Rudolph, K. (2009). Adolescent depression. In Gotlib, I. H. & Hammen, C. L. (Eds.), Handbook of depression (2nd ed., pp. 444–466). New York: Guilford Press.Google Scholar
Sameroff, A. J. (1975). Early influences on development: Fact or fancy? Merrill–Palmer Quarterly, 21, 267–294.Google Scholar
Seifer, R., Dickstein, S., Sameroff, A. J., Magee, K. D., & Hayden, L. C. (2001). Infant mental health and variability of parental depressive symptoms. Journal of the American Academy of Child & Adolescent Psychiatry, 40, 1375–1382.CrossRefGoogle Scholar
Serbin, L., & Karp, J. (2004). The intergenerational transfer of psychosocial risk: Mediators of vulnerability and resilience. Annual Review of Psychology, 55, 333–363.CrossRefGoogle ScholarPubMed
Sheeber, L., Hops, H., & Davis, B. (2001). Family processes in adolescent depression. Clinical Child and Family Psychology Review, 4, 19–35.CrossRefGoogle ScholarPubMed
Spitzer, R. L., Williams, J. B. W., Gibbon, M., & First, M. B. (1990). User's guide for the Structured Clinical Interview for DSM-III-R. Washington, DC: American Psychiatric Press.Google Scholar
Tamis-LeMonda, C. S., & Cabrera, N. 2002. Handbook of father involvement: Multidisciplinary perspectives. Mahwah, NJ: Erlbaum.Google Scholar
Taylor, L., & Ingram, R. E. (1999). Cognitive reactivity and depressotypic information processing in children of depressed mothers. Journal of Abnormal Psychology, 108, 202–210.CrossRefGoogle ScholarPubMed
Weissman, M. M., Warner, V., Wickramaratne, P., Moreau, D., & Olfson, M. (1997). Offspring of depressed patients: 10 years later. Archives of General Psychiatry, 54, 932–940.CrossRefGoogle Scholar
Weissman, M. M., Wickramaratne, P., Nomura, Y., Warner, V., Pilowsky, D., & Verdeli, H. (2006). Offspring of depressed parents: 20 years later. American Journal of Psychiatry, 163, 1001–1008.CrossRefGoogle ScholarPubMed
Weissman, M. M., Wolk, S., Goldstein, R. B., Moreau, D., Adams, P., Greenwald, S., et al. (1999). Depressed adolescents grown up. Journal of the American Medical Association, 281, 1707–1713.CrossRefGoogle ScholarPubMed