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The interaction between parenting and children's cortisol reactivity at age 3 predicts increases in children's internalizing and externalizing symptoms at age 6

Published online by Cambridge University Press:  14 March 2017

Chelsey S. Barrios ,
Sara J. Bufferd ,
Daniel N. Klein  and
Lea R. Dougherty
Chelsey S. Barrios
Affiliation:
University of Maryland College Park
Sara J. Bufferd
Affiliation:
California State University, San Marcos
Daniel N. Klein
Affiliation:
Stony Brook University
Lea R. Dougherty*
Affiliation:
University of Maryland College Park
*
Address correspondence and reprint requests to: Lea R. Dougherty, Department of Psychology, University of Maryland, College Park, MD 20742; E-mail: [email protected].
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Abstract

Little is known about the role of stress reactivity in the emergence of psychopathology across early childhood. In this longitudinal study, we tested the hypothesis that child cortisol reactivity at age 3 moderates associations between early parenting and children's internalizing and externalizing symptoms from age 3 to age 6. One hundred and sixty children were assessed at age 3, and 135 children were reassessed at age 6. At age 3, we exposed children to stress-inducing laboratory tasks, during which we obtained four salivary cortisol samples, and parental hostility was assessed using an observational parent–child interaction task. At ages 3 and 6, child psychiatric symptoms were assessed using a clinical interview with parents. The results indicated that the combination of high child cortisol reactivity and high observed parental hostility at age 3 was associated with greater concurrent externalizing symptoms at age 3 and predicted increases in internalizing and externalizing symptoms from age 3 to age 6. Findings highlight that increased stress reactivity, within the context of hostile parenting, plays a role in the emergence of psychopathology from preschool to school entry.

Type
Regular Articles
Information
Development and Psychopathology , Volume 29 , Issue 4 , October 2017 , pp. 1319 - 1331
Copyright
Copyright © Cambridge University Press 2017 

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Footnotes

We are grateful to all of the families who took part in the study and to the Stony Brook Temperament Study research team. This research was supported by R01MH069942 (to D.N.K.), F31MH075484 (to L.R.D.), F31MH084444 (to S.J.B.), and General Clinical Research Center Grant M01RR10710 (Stony Brook University, National Center for Research Resources). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Mental Health or the National Institutes of Health. The authors report no conflicts of interest.

References

Acock, A. C. (2005). Working with missing values. Journal of Marriage and Family, 67, 1012–1028. doi:10.1111/j.1741-3737.2005.00191.x CrossRefGoogle Scholar
Aiken, L. S., & West, S. G. (1991). Multiple regression: Testing and interpreting interactions. Newbury Park, CA: Sage.Google Scholar
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.Google Scholar
Badanes, L. S., Watamura, S. E., & Hankin, B. L. (2011). Hypocortisolism as a potential marker of allostatic load in children: Associations with family risk and internalizing disorders. Development and Psychopathology, 23, 881–896. doi:10.1017/S095457941100037X CrossRefGoogle ScholarPubMed
Belsky, J. (2005). Differential susceptibility to rearing influences: An evolutionary hypothesis and some evidence. In Ellis, B. & Bjorklund, D. (Eds.), Origins of the social mind: Evolutionary psychology and child development (pp. 139–163). New York: Guilford Press.Google Scholar
Belsky, J., & Pluess, M. (2009). Beyond diathesis stress: Differential susceptibility to environmental influences. Psychological Bulletin, 135, 885–908. doi:10.1037/a0017376 CrossRefGoogle ScholarPubMed
Booij, S. H., Bouma, E. C., de Jonge, P., Ormel, J., & Oldehinkel, A. J. (2013). Chronicity of depressive problems and the cortisol response to psychosocial stress in adolescents: The TRAILS study. Psychoneuroendocrinology, 38, 659–666. doi:10.1016/j.psyneuen.2012.08.004 CrossRefGoogle ScholarPubMed
Boyce, W. T., & Ellis, B. J. (2005). Biological sensitivity to context: I. An evolutionary developmental theory of the origins and functions of stress reactivity. Development and Psychopathology, 17, 271–301. doi:10.1017/S0954579405050145 CrossRefGoogle ScholarPubMed
Bradley, R. H., & Corwyn, R. F. (2002). Socioeconomic status and child development. Annual Review of Psychology, 53, 371–399. doi:10.1146/annurev.psych.53.100901.135233 CrossRefGoogle ScholarPubMed
Brennan, P. A., Pargas, R., Walker, E., Green, P., Newport, D. J., & Stowe, Z. (2008). Maternal depression and infant cortisol: Influences of timing, comorbidity and treatment. Journal of Child Psychology and Psychiatry, 49, 1099–1107. doi:10.1111/j.1469-7610.2008.01914.x CrossRefGoogle ScholarPubMed
Bufferd, S. J., Dougherty, L. R., Carlson, G. A., & Klein, D. N. (2011). Parent-reported mental health in preschoolers: Findings using a diagnostic interview. Comprehensive Psychiatry, 52, 359–369. doi:10.1016/j.comppsych.2010.08.006 CrossRefGoogle ScholarPubMed
Bufferd, S. J., Dougherty, L. R., Carlson, G. A., Rose, S., & Klein, D. N. (2012). Psychiatric disorders in preschoolers: Continuity from ages 3 to 6. American Journal of Psychiatry, 169, 1157–1164. doi:10.1176/appi.ajp.2012.12020268 CrossRefGoogle ScholarPubMed
Carr, C. P., Martins, C. M., Stingel, A. M., Lemgruber, V. B., & Juruena, M. F. (2013). The role of early life stress in adult psychiatric disorders: A systematic review according to childhood trauma subtypes. Journal of Nervous and Mental Disease, 201, 1007–1020. doi:10.1097/NMD.0000000000000049 CrossRefGoogle ScholarPubMed
Chronis-Tuscano, A., Molina, B. G., Pelham, W. E., Applegate, B., Dahlke, A., Overmyer, M., & Lahey, B. (2010). Very early predictors of adolescent depression and suicide attempts in children attention-deficit/hyperactivity disorder. Archives of General Psychiatry, 67, 1044–1051. doi:10.1001/archgenpsychiatry.2010.127 CrossRefGoogle Scholar
Dedovic, K., Duchesne, A., Andrews, J., Engert, V., & Pruessner, J. C. (2009). The brain and the stress axis: The neural correlates of cortisol regulation in response to stress. NeuroImage, 47, 864–871. doi:10.1016/j.neuroimage.2009.05.074 CrossRefGoogle ScholarPubMed
de Veld, D. M., Riksen-Walraven, J. M., & de Weerth, C. (2012). The relation between emotion regulation strategies and physiological stress responses in middle childhood. Psychoneuroendocrinology, 37, 1309–1319. doi:10.1016/j.psyneuen.2012.01.004 CrossRefGoogle ScholarPubMed
Dickerson, S. S., & Kemeny, M. E. (2004). Acute stressors and cortisol responses: A theoretical integration and synthesis of laboratory research. Psychological Bulletin, 130, 355–391. doi:10.1037/0033-2909.130.3.355 CrossRefGoogle ScholarPubMed
Dougherty, L. R., Bufferd, S. J., Carlson, G. A., Dyson, M., Olino, T. M., Durbin, E. C., & Klein, D. N. (2011). Preschoolers’ observed temperament and psychiatric disorders assessed with a parent diagnostic interview. Journal of Clinical Child and Adolescent Psychology, 40, 295–306. doi:10.1080/15374416.2011.546046 CrossRefGoogle ScholarPubMed
Dougherty, L. R., Klein, D. N., Congdon, E., Canli, T., & Hayden, E. P. (2010). Interaction between 5-HTTLPR and BDNF Val66Met polymorphisms on HPA axis reactivity in preschoolers. Biological Psychology, 83, 93–100. doi:10.1016/j.biopsycho.2009.10.009 CrossRefGoogle ScholarPubMed
Dougherty, L. R., Klein, D. N., Rose, S., & Laptook, R. S. (2011). Hypothalamic-pituitary-adrenal axis reactivity in the preschool-age offspring of depressed parents: Moderation by early parenting. Psychological Science, 22, 650–658. doi:10.1177/0956797611404084 CrossRefGoogle ScholarPubMed
Dougherty, L. R., Leppert, K. A., Merwin, S. M., Smith, V. C., Bufferd, S. J., & Kushner, M. R. (2015). Advances and directions in preschool mental health research. Child Development Perspectives, 9, 14–19. doi:10.1111/cdep.12099 CrossRefGoogle Scholar
Dougherty, L. R., Smith, V. C., Bufferd, S. J., Kessel, E., Carlson, G. A., & Klein, D. N. (2015). Preschool irritability predicts child psychopathology, functional impairment, and service use at age nine. Journal of Child Psychology and Psychiatry, 56, 999–1007. doi:10.1111/jcpp.12403 CrossRefGoogle ScholarPubMed
Dougherty, L. R., Smith, V. C., Bufferd, S. J., Stringaris, A., Leibenluft, E., Carlson, G. A., & Klein, D. N. (2013). Preschool irritability: Longitudinal associations with psychiatric disorders at age 6 and parental psychopathology. Journal of the American Academy of Child & Adolescent Psychiatry, 52, 1304–1313. doi:10.1016/j.jaac.2013.09.007 CrossRefGoogle ScholarPubMed
Dougherty, L. R., Tolep, M. R., Smith, V. C., & Rose, S. (2013). Early exposure to parental depression and parenting: Associations with young offspring's stress physiology and oppositional behavior. Journal of Abnormal Child Psychology, 41, 1299–1310. doi:10.1007/s10802-013-9763-7 CrossRefGoogle ScholarPubMed
Doussard-Roosevelt, J. A., Montgomery, L. A., & Porges, S. W. (2003). Short-term stability of physiological measures in kindergarten children: Respiratory sinus arrhythmia, heart period, and cortisol. Developmental Psychobiology, 43, 230–242. doi:10.1002/dev.10136 CrossRefGoogle ScholarPubMed
Dunn, L. M., & Dunn, L. M. (1997). Peabody Picture Vocabulary Test (3rd ed.). Circle Pines, MN: American Guidance Service.Google Scholar
Egeland, B., Weinfield, N., Hiester, M., Lawrence, C., Pierce, S., & Chippendale, K. (1995). Teaching tasks administration and scoring manual. Unpublished manuscript, University of Minnesota.Google Scholar
Egger, H. L., & Angold, A. (2006). Common emotional and behavioral disorders in preschool children: Presentation, nosology, and epidemiology. Journal of Child Psychology and Psychiatry, 47, 313–337. doi:10.1111/j.1469-7610.2006.01618.x CrossRefGoogle ScholarPubMed
Egger, H. L., Ascher, B. H., & Angold, A. (1999). The Preschool Age Psychiatric Assessment: Version 1.1. Durham, NC: Duke University Medical Center, Center for Developmental Epidemiology, Department of Psychiatry and Behavioral Sciences.Google Scholar
Egger, H. L., Erkanli, A., Keeler, G., Potts, E., Walter, B. K., & Angold, A. (2006). Test-retest reliability of the Preschool Age Psychiatric Assessment (PAPA). Journal of the American Academy of Child & Adolescent Psychiatry, 45, 538–549. doi:10.1097/01.chi.0000205705.71194.b8 CrossRefGoogle ScholarPubMed
Essex, M. J., Armstrong, J. M., Burk, L. R., Goldsmith, H. H., & Boyce, W. T. (2011). Biological sensitivity to context moderates the effects of the early teacher–child relationship on the development of mental health by adolescence. Development and Psychopathology, 23, 149–161. doi:10.1017/S0954579410000702 CrossRefGoogle ScholarPubMed
Gadow, K. D., & Sprafkin, J. (2000). Early Childhood Inventory—4 screening manual. Stony Brook, NY: Checkmate Plus.Google Scholar
Goldsmith, H. H., Reilly, J., Lemery, K. S., Longley, S., & Prescott, A. (1995). The Laboratory Temperament Assessment Battery: Preschool version. Unpublished manuscript.Google Scholar
Gotlib, I. H., Joormann, J., Minor, K. L., & Cooney, R. E. (2006). Cognitive and biological functioning in children at risk for depression. In Canli, T. & Canli, T. (Eds.), Biology of personality and individual differences (pp. 353–382). New York: Guilford Press.Google Scholar
Granger, D. A., Weisz, J. R., McCracken, J. T., Ikeda, S. C., & Douglas, P. (1996). Reciprocal influences among adrenocortical activation, psychosocial processes, and the behavioral adjustment of clinic-referred children. Child Development, 76, 3250–3262. doi:10.2307/1131777 CrossRefGoogle Scholar
Gunnar, M. R., & Talge, N. M. (2007). Neuroendocrine measures in developmental research. In Schmidt, L. A. & Segalowitz, S. J. (Eds.), Developmental psychophysiology: Theory, systems, and methods (pp. 343–366). Cambridge: Cambridge University Press.CrossRefGoogle Scholar
Gunnar, M. R., Talge, N. M., & Herrera, A. (2009). Stressor paradigms in developmental studies: What does and does not work to produce mean increases in salivary cortisol. Psychoneuroendocrinology, 34, 953–967. doi:10.1016/j.psyneuen.2009.02.010 CrossRefGoogle Scholar
Gunnar, M. R., & Vazquez, D. M. (2006). Stress neurobiology and developmental psychopathology. In Cicchetti, D. & Cohen, D. J. (Eds.), Developmental psychopathology: Vol. 2. Developmental neuroscience (2nd ed., pp. 533–577). Hoboken, NJ: Wiley.Google Scholar
Gunnar, M. R., Wewerka, S., Frenn, K., Long, J. D., & Griggs, C. (2009). Developmental changes in hypothalamus–pituitary–adrenal activity over the transition to adolescence: Normative changes and associations with puberty. Development and Psychopathology, 21, 69–85. doi:10.1017/S0954579409000054 CrossRefGoogle ScholarPubMed
Hagan, M. J., Roubinov, D. S., Mistler, A. K., & Luecken, L. J. (2014). Mental health outcomes in emerging adults exposed to childhood maltreatment: The moderating role of stress reactivity. Child Maltreatment, 19, 156–167. doi:10.1177/1077559514539753 CrossRefGoogle ScholarPubMed
Hankin, B. L., Badanes, L. S., Abela, J. R., & Watamura, S. E. (2010). Hypothalamic–pituitary–adrenal axis dysregulation in dysphoric children and adolescents: Cortisol reactivity to psychosocial stress from preschool through middle adolescence. Biological Psychiatry, 68, 484–490. doi:10.1016/j.biopsych.2010.04.004 CrossRefGoogle ScholarPubMed
Harkness, K. L., Stewart, J. G., & Wynne-Edwards, K. E. (2011). Cortisol reactivity to social stress in adolescents: Role of depression severity and child maltreatment. Psychoneuroendocrinology, 36, 173–181. doi:10.1016/j.psyneuen.2010.07.006 CrossRefGoogle ScholarPubMed
Hastings, P. D., Ruttle, P. L., Serbin, L. A., Mills, R. S., Stack, D. M., & Schwartzman, A. E. (2011). Adrenocortical responses to strangers in preschoolers: Relations with parenting, temperament, and psychopathology. Developmental Psychobiology, 53, 694–710. doi:10.1002/dev.20545 CrossRefGoogle ScholarPubMed
Hayes, A. F., & Matthes, J. (2009). Computational procedures for probing interactions in OLS and logistic regression: SPSS and SAS implementations. Behavioral Research Methods, 41, 924–936. doi:10.3758/BRM.41.3.924 CrossRefGoogle ScholarPubMed
Hollingshead, A. (1975). Four Factor Index of Social Status. Unpublished manuscript, Yale University.Google Scholar
Humphreys, K. L., & Zeanah, C. H. (2015). Deviations from the expectable environment in early childhood and emerging psychopathology. Neuropsychopharmacology, 40, 154–170. doi:10.1038/npp.2014.165 CrossRefGoogle ScholarPubMed
Johnson, P. O., & Fay, L. C. (1950). The Johnson–Neyman technique, its theory and application. Psychometrika, 15, 349–367. doi:10.1038/npp.2014.165 CrossRefGoogle ScholarPubMed
Kryski, K. R., Dougherty, L. R., Dyson, M. W., Olino, T. M., Laptook, R. S., Klein, D. N., & Hayden, E. P. (2013). Effortful control and parenting: Associations with HPA axis reactivity in early childhood. Developmental Science, 16, 531–541. doi:10.1111/desc.12050 CrossRefGoogle ScholarPubMed
Kryski, K. R., Smith, H. J., Sheikh, H. I., Singh, S. M., & Hayden, E. P. (2011). Assessing stress reactivity indexed via salivary cortisol in preschool-aged children. Psychoneuroendocrinology, 36, 1127–1136. doi:10.1016/j.psyneuen.2011.02.003 CrossRefGoogle ScholarPubMed
Kryski, K. R., Smith, H. J., Sheikh, H. I., Singh, S. M., & Hayden, E. P. (2013). HPA axis reactivity in early childhood: Associations with symptoms and moderation by sex. Psychoneuroendocrinology, 38, 2327–2336.CrossRefGoogle ScholarPubMed
Kushner, M., Barrios, C., Smith, V. C., & Dougherty, L. R. (2016). Physiological and behavioral vulnerability markers increase risk to early life stress in preschool-aged children. Journal of Abnormal Child Psychology, 44, 859–870. doi:10.1007/s10802-015-0087-7 CrossRefGoogle ScholarPubMed
Lahey, B. B., Pelham, W. E., Loney, J., Kipp, H., Ehrhardt, A., Lee, S. L., … Massetti, G. (2004). Three-year predictive validity of DSM-IV attention deficit hyperactivity disorder in children diagnosed at 4-6 years of age. American Journal of Psychiatry, 161, 2014–2020. doi:10.1176/appi.ajp.161.11.2014 CrossRefGoogle ScholarPubMed
Lam, S., Dickerson, S. S., Zoccola, P. M., & Zaldivar, F. (2009). Emotion regulation and cortisol reactivity to a social-evaluative speech task. Psychoneuroendocrinology, 34, 1355–1362. doi:10.1016/j.psyneuen.2009.04.006 CrossRefGoogle ScholarPubMed
Latimer, K., Wilson, P., Kemp, J., Thompson, L., Sim, F., Gillberg, C., … Minnis, H. (2012). Disruptive behaviour disorders: A systematic review of environmental antenatal and early years risk factors. Child: Care, Health and Development, 38, 611–628. doi:10.1111/j.1365-2214.2012.01366.x CrossRefGoogle ScholarPubMed
Lavigne, J. V., Arend, R., Rosenbaum, D., Binns, H. J., Christoffel, K. K., & Gibbons, R. D. (1998). Psychiatric disorders with onset in the preschool years: I. Stability of diagnoses. Journal of the American Academy of Child & Adolescent Psychiatry, 37, 1246–1254. doi:10.1097/00004583-199812000-00007 CrossRefGoogle ScholarPubMed
Lavigne, J. V., Cicchetti, C., Gibbons, R. D., Binns, H. J., Larsen, L., & DeVito, C. (2001). Oppositional defiant disorder with onset in preschool years: Longitudinal stability and pathways to other disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 40, 1393–1400. doi:10.1097/00004583-200112000-00009 CrossRefGoogle ScholarPubMed
Luby, J. L., Gaffrey, M. S., Tillman, R., April, L. M., & Belden, A. C. (2014). Trajectories of preschool disorders to full DSM depression at school age and early adolescence: Continuity of preschool depression. American Journal of Psychiatry, 171, 768–776. doi:10.1176/appi.ajp.2014.13091198 CrossRefGoogle ScholarPubMed
Luby, J. L., Heffelfinger, A., Mrakotsky, C., Brown, K., Hessler, M., & Spitznagel, E. (2003). Alterations in stress cortisol reactivity in depressed preschoolers relative to psychiatric and no-disorder comparison groups. Archives of General Psychiatry, 60, 1248–1255. doi:10.1001/archpsyc.60.12.1248 CrossRefGoogle ScholarPubMed
Luby, J. L., Si, X., Belden, A. C., Tandon, M., & Spitznagel, E. (2009). Preschool depression: Homotypic continuity and course over 24 months. Archives of General Psychiatry, 66, 897–905. doi:10.1001/archgenpsychiatry.2009.97 CrossRefGoogle ScholarPubMed
Lyneham, H. J., & Rapee, R. M. (2005). Agreement between telephone and in-person delivery of a structured interview for anxiety disorders in children. Journal of the American Academy of Child & Adolescent Psychiatry, 44, 274–282. doi:10.1097/00004583-200503000-00012 CrossRefGoogle ScholarPubMed
McKee, L., Colletti, C., Rakow, A., Jones, D. J., & Forehand, R. (2008). Parenting and child externalizing behaviors: Are the associations specific or diffuse? Aggression and Violent Behavior, 13, 201–215. doi:10.1016/j.avb.2008.03.005 CrossRefGoogle ScholarPubMed
McLaughlin, K. A., & King, K. (2015). Developmental trajectories of anxiety and depression in early adolescence. Journal of Abnormal Child Psychology, 43, 311–323. doi:10.1007/s10802-014-9898-1 CrossRefGoogle ScholarPubMed
McLeod, B. D., Weisz, J. R., & Wood, J. J. (2007). Examining the association between parenting and childhood depression: A meta-analysis. Clinical Psychology Review, 27, 986–1003. doi:10.1016/j.cpr.2007.03.001 CrossRefGoogle ScholarPubMed
Mesman, J., Bongers, I. L., & Koot, H. M. (2001). Preschool developmental pathways to preadolescent internalizing and externalizing problems. Journal of Child Psychology and Psychiatry, 42, 679–689. doi:10.1111/1469-7610.00763 CrossRefGoogle ScholarPubMed
Monroe, S. M., & Reid, M. W. (2009). Life stress and major depression. Current Directions in Psychological Science, 18, 68–72. doi:10.1111/j.1467-8721.2009.01611.x CrossRefGoogle Scholar
Monroe, S. M., & Simons, A. D. (1991). Diathesis–stress theories in the context of life stress research: Implications for the depressive disorders. Psychological Bulletin, 110, 406–425. doi:10.1037/0033-2909.110.3.406 CrossRefGoogle ScholarPubMed
Morgan, J. K., Shaw, D. S., & Olino, T. M. (2012). Differential susceptibility effects: The interaction of negative emotionality and sibling relationship quality on childhood internalizing problems and social skills. Journal of Abnormal Child Psychology, 40, 885–899. doi:10.1007/s10802-012-9618-7 CrossRefGoogle ScholarPubMed
Morris, C. M., Rao, U., & Garber, J. (2012). Cortisol responses to psychosocial stress predict depression trajectories: Social-evaluative threat and prior depressive episodes as moderators. Journal of Affective Disorders, 143, 223–230. doi:10.1016/j.jad.2012.05.059 CrossRefGoogle ScholarPubMed
Murri, M., Pariante, C., Mondelli, V., Masotti, M., Atti, A. R., Mellacqua, A., … Amore, M. (2014). HPA axis and aging in depression: Systematic review and meta-analysis. Psychoneuroendocrinology, 41, 46–62. doi:10.1016/j.psyneuen.2013.12.004 CrossRefGoogle Scholar
Navarro, Pastor J. B. (2003). Methods for the analysis of explanatory linear regression models with missing data not at random. Quality and Quantity, 37, 363–376. doi:10.1023/A:1027323122628 CrossRefGoogle Scholar
Obradović, J., Bush, N. R., Stamperdahl, J., Adler, N. E., & Boyce, W. T. (2010). Biological sensitivity to context: The interactive effects of stress reactivity and family adversity on socio-emotional behavior and school readiness. Child Development, 81, 270–289. doi:10.1111/j.1467-8624.2009.01394.x CrossRefGoogle Scholar
Okado, Y., & Bierman, K. L. (2015). Differential risk for late adolescent conduct problems and mood dysregulation among children with early externalizing behavior problems. Journal of Abnormal Child Psychology, 43, 735–747.CrossRefGoogle ScholarPubMed
Olino, T. M., Dougherty, L. R., Bufferd, S. J., Carlson, G. A., & Klein, D. N. (2014). Testing models of psychopathology in preschool-aged children using a structured interview-based assessment. Journal of Abnormal Child Psychology, 42, 1201–1211. doi:10.1007/s10802-014-9865-x CrossRefGoogle ScholarPubMed
Olino, T. M., Klein, D. N., Dyson, M. W., Rose, S. A., & Durbin, E. C. (2010). Temperamental emotionality in preschool-aged children and depressive disorders in parents: Associations in a large community sample. Journal of Abnormal Psychology, 119, 468–478. doi:10.1037/a0020112 CrossRefGoogle Scholar
O'Neal, C. R., Brotman, L. M., Huang, K. Y., Gouley, K. K., Kamboukos, D., Calzada, E. J., & Pine, D. S. (2010). Understanding relations among early family environment, cortisol response, and child aggression via a prevention experiment. Child Development, 81, 290–305. doi:10.1111/j.1467-8624.2009.01395.x CrossRefGoogle Scholar
Pariante, C. M. (2003). Depression, stress, and the adrenal axis. Journal of Neuroendocrinology, 15, 811–812.Google ScholarPubMed
Pruessner, J. C., Kirschbaum, C., Meinlschmid, G., & Hellhammer, D. H. (2003). Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendocrinology, 28, 916–931. doi:10.1016/S0306-4530(02)00108-7 CrossRefGoogle ScholarPubMed
Rao, U., Hammen, C., Ortiz, L. R., Chen, L. A., & Poland, R. E. (2008). Effects of early and recent adverse experiences on adrenal response to psychosocial stress in depressed adolescents. Biological Psychiatry, 64, 521–526. doi:10.1016/j.biopsych.2008.05.012 CrossRefGoogle ScholarPubMed
Repetti, R. L., Taylor, S. E., & Seeman, T. E. (2002). Risky families: Family social environments and the mental and physical health of offspring. Psychological Bulletin, 128, 330–366. doi:10.1037/0033-2909.128.2.330 CrossRefGoogle ScholarPubMed
Saxbe, D. E., Margolin, G., Spies Shapiro, L. A., & Baucom, B. R. (2012). Does dampened physiological reactivity protect youth in aggressive family environments? Child Development, 83, 821–830. doi:10.1111/j.1467-8624.2012.01752.x CrossRefGoogle ScholarPubMed
Sprafkin, J., Volpe, R. J., Gadow, K. D., Nolan, E. E., & Kelly, K. (2002). A DSM-IV referenced screening instrument for preschool children: The Early Childhood Inventory—4. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 604–612. doi:10.1097/00004583-200205000-00018 CrossRefGoogle ScholarPubMed
Steeger, C. M., Cook, E. C., & Connell, C. M. (2016). The interactive effects of stressful family life events and cortisol reactivity on adolescent externalizing and internalizing behaviors. Child Psychiatry & Human Development. Advance online publication. doi:10.1007/s10578-016-0635-6 Google Scholar
Sterba, S., Egger, H. L., & Angold, A. (2007). Diagnostic specificity and nonspecificity in the dimensions of preschool psychopathology. Journal of Child Psychology and Psychiatry, 48, 1005–1013. doi:10.1111/j.1469-7610.2007.01770.x CrossRefGoogle ScholarPubMed
Susman, E. J., Dorn, L. D., Inoff-Germain, G., Nottelmann, E. D., & Chrousos, G. P. (1997). Cortisol reactivity, distress behavior, and behavioral psychological problems in young adolescents: A longitudinal perspective. Journal of Research on Adolescence, 7, 81–105. doi:10.1207/s15327795jra0701_5 CrossRefGoogle Scholar
Talge, N. M., Donzella, B., & Gunnar, M. R. (2008). Fearful temperament and stress reactivity among preschool-aged children. Infant and Child Development, 17, 427–445. doi:10.1002/icd.585 CrossRefGoogle ScholarPubMed
Talge, N. M., Donzella, B., Kryzer, E. M., Gierens, A., & Gunnar, M. R. (2005). It's not that bad: Error introduced by oral stimulants in salivary cortisol research. Developmental Psychobiology, 47, 369–376. doi:10.1002/dev.20097 CrossRefGoogle Scholar
van De Wiel, N. H., van Goozen, S. M., Matthys, W., Snoek, H., & van Engeland, H. (2004). Cortisol and treatment effect in children with disruptive behavior disorders: A preliminary study. Journal of the American Academy of Child & Adolescent Psychiatry, 43, 1011–1018. doi:10.1097/01.chi.0000126976.56955.43 CrossRefGoogle ScholarPubMed
van Leeuwen, A. P., Creemers, H. E., Greaves-Lord, K., Verhulst, F. C., Ormel, J., & Huizink, A. C. (2011). Hypothalamic–pituitary–adrenal axis reactivity to social stress and adolescent cannabis use: The TRAILS study. Addiction, 106, 1484–1492. doi:10.1111/j.1360-0443.2011.03448.x CrossRefGoogle ScholarPubMed
von Klitzing, K.V., Perren, S., Klein, A. M., Stadelmann, S., White, L. O., Groeben, M., … Hatzinger, M. (2012). The interaction of social risk factors and HPA axis dysregulation in predicting emotional symptoms of five- and six-year-old children. Journal of Psychiatric Research, 46, 290–297. doi:10.1016/j.jpsychires.2011.12.004 CrossRefGoogle ScholarPubMed
Wichstrøm, L., Berg-Nielsen, T. S., Angold, A., Egger, H. L., Solheim, E., & Sveen, T. H. (2012). Prevalence of psychiatric disorders in preschoolers. Journal of Child Psychology and Psychiatry, 53, 695–705. doi:10.1111/j.1469-7610.2011.02514.x CrossRefGoogle ScholarPubMed