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Observational measures of early irritability predict children's psychopathology risk

Published online by Cambridge University Press:  20 May 2021

Ola Mohamed Ali Open the ORCID record for Ola Mohamed Ali [Opens in a new window] ,
Lindsay N. Gabel Open the ORCID record for Lindsay N. Gabel [Opens in a new window] ,
Kasey Stanton ,
Erin A. Kaufman ,
Daniel N. Klein  and
Elizabeth P. Hayden Open the ORCID record for Elizabeth P. Hayden [Opens in a new window]
Ola Mohamed Ali*
Affiliation:
Department of Psychology, Brain and Mind Institute, University of Western Ontario, London, ON, Canada
Lindsay N. Gabel
Affiliation:
Department of Psychology, Brain and Mind Institute, University of Western Ontario, London, ON, Canada
Kasey Stanton
Affiliation:
Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
Erin A. Kaufman
Affiliation:
Department of Psychology, Brain and Mind Institute, University of Western Ontario, London, ON, Canada
Daniel N. Klein
Affiliation:
Department of Psychology, Stony Brook University, The State University of New York, Stony Brook, NY, USA
Elizabeth P. Hayden
Affiliation:
Department of Psychology, Brain and Mind Institute, University of Western Ontario, London, ON, Canada
*
Author for Correspondence: Ola Mohamed Ali; E-mail: [email protected]
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Abstract

Irritability is a transdiagnostic feature of diverse forms of psychopathology and a rapidly growing literature implicates the construct in child maladaptation. However, most irritability measures currently used are drawn from parent-report questionnaires not designed to measure irritability per se; furthermore, parent report methods have several important limitations. We therefore examined the utility of observational ratings of children's irritability in predicting later psychopathology symptoms. Four-hundred and nine 3-year-old children (208 girls) completed observational tasks tapping temperamental emotionality and parents completed questionnaires assessing child irritability and anger. Parent-reported child psychopathology symptoms were assessed concurrently to the irritability assessment and when children were 5 and 8 years old. Children's irritability observed during tasks that did not typically elicit anger predicted their later depressive and hyperactivity symptoms, above and beyond parent-reported irritability and context-appropriate observed anger. Our findings support the use of observational indices of irritability and have implications for the development of observational paradigms designed to assess this construct in childhood.

Keywords

childrendevelopmentirritabilitymeasurementobservationalparent report
Type
Regular Article
Information
Development and Psychopathology , Volume 34 , Issue 4 , October 2022 , pp. 1531 - 1543
Copyright
© The Author(s), 2021. Published by Cambridge University Press

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References

Achenbach, T. M. (1991). Manual for the child behavior checklist/4-18 and 1991 profile. Burlington: University of Vermont.Google Scholar
Achenbach, T. M. (1992). Manual for the child behavior checklist/2–3 and 1992 profile. University of Vermont: Burlington.Google Scholar
Angold, A., Prendergast, M., Cox, A., Harrington, R., Simonoff, E., & Rutter, M. (1995). The child and adolescent psychiatric assessment (CAPA). Psychological Medicine, 25, 739–753. doi:10.1097/00004583-200001000-00015CrossRefGoogle Scholar
Avenevoli, S., Blader, J. C., & Leibenluft, E. (2015). Irritability in youth: An update. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 881–883. doi:10.1016/j.jaac.2015.08.012CrossRefGoogle ScholarPubMed
Beauchaine, T. P., & Tackett, J. L. (2019). Irritability as a transdiagnostic vulnerability trait: Current issues and future directions. Behavior Therapy, doi:10.1016/j.beth.2019.10.009Google ScholarPubMed
Brotman, M. A., Kircanski, K., & Leibenluft, E. (2017). Irritability in children and adolescents. Annual Review of Clinical Psychology, 13, 317–341. doi:10.1146/annurev-clinpsy-032816-044941CrossRefGoogle ScholarPubMed
Buss, K. A., Davis, E. L., Ram, N., & Coccia, M. (2018). Dysregulated fear, social inhibition, and respiratory Sinus arrhythmia: A replication and extension. Child Development, 89, e214–e228. doi:10.1111/cdev.12774CrossRefGoogle Scholar
Clark, L. A. (2005). Temperament as a unifying basis for personality and psychopathology. Journal of Abnormal Psychology, 114, 505–521. doi:10.1037/0021-843X.114.4.505Google ScholarPubMed
Clark, D. A., Durbin, C. E., Donnellan, M. B., & Neppl, T. K. (2017). Internalizing symptoms and personality traits color parental reports of child temperament. Journal of Personality, 85, 852–866. doi:10.1111/jopy.12293CrossRefGoogle ScholarPubMed
Clark, L. A., & Watson, D. (2019). Constructing validity: New developments in creating objective measuring instruments. Psychological Assessment, 1, 999. doi:10.1037/pas0000626Google Scholar
Clifford, S., Lemery-Chalfant, K., & Goldsmith, H. H. (2015). The unique and shared genetic and environmental contributions to fear, anger, and sadness in childhood. Child Development, 86, 1538–1556. doi:10.1111/cdev.12394CrossRefGoogle ScholarPubMed
Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2d ed.). New Jersey: Lawrence Erlbaum Associates Inc.Google Scholar
Copeland, W. E., Brotman, M. A., & Costello, E. J. (2015). Normative irritability in youth: Developmental findings from the great smoky mountains study. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 635–642. doi:10.1016/j.jaac.2015.05.008CrossRefGoogle ScholarPubMed
Craig, K. J., Hietanen, H., Markova, I. S., & Berrios, G. E. (2008). The irritability questionnaire: A new scale for the measurement of irritability. Psychiatry Research, 159, 367–375. doi:10.1016/j.psychres.2007.03.002CrossRefGoogle ScholarPubMed
De Los Reyes, A., & Kazdin, A. E. (2005). Informant discrepancies in the assessment of childhood psychopathology: A critical review, theoretical framework, and recommendations for further study. Psychological Bulletin, 131, 483–509. doi:10.1037/0033-2909.131.4.483CrossRefGoogle ScholarPubMed
Deveney, C. M., Connolly, M. E., Haring, C. T., Bones, B. L., Reynolds, R. C., Kim, P., … Leibenluft, E. (2013). Neural mechanisms of frustration in chronically irritable children. American Journal of Psychiatry, 170, 1186–1194. doi:10.1176/appi.ajp.2013.12070917CrossRefGoogle ScholarPubMed
Deveney, C. M., Grasso, D., Hsu, A., Pine, D. S., Estabrook, C. R., Zobel, E., … Briggs-Gowan, M. J. (2019). Multi-method assessment of irritability and differential linkages to neurophysiological indicators of attention allocation to emotional faces in young children. Developmental Psychobiology, 62, 600–616. doi:10.1002/dev.21930CrossRefGoogle ScholarPubMed
Dougherty, L. R., Smith, V. C., Bufferd, S. J., Kessel, E., Carlson, G. A., & Klein, D. N. (2015). Preschool irritability predicts child psychopathology, functional impairment, and service use at age nine. Journal of Child Psychology and Psychiatry and Allied Disciplines, 56, 999–1007. doi:10.1111/jcpp.12403CrossRefGoogle ScholarPubMed
Dougherty, L. R., Smith, V. C., Bufferd, S. J., Stringaris, A., Leibenluft, E., Carlson, G. A., & Klein, D. N. (2013). Preschool irritability: Longitudinal associations With psychiatric disorders at age 6 and parental psychopathology. Journal of the American Academy of Child & Adolescent Psychiatry, 52, 1304–1313. doi:10.1016/j.jaac.2013.09.007CrossRefGoogle ScholarPubMed
Dunn, L., & Dunn, D. (1997). PPVT III: Peabody picture vocabulary test (3rd ed.). Circle Pines, MN: Guidance Service Circle.Google Scholar
Durbin, C. E., Hayden, E. P., Klein, D. N., & Olino, T. M. (2007). Stability of laboratory-assessed temperamental emotionality traits from ages 3 to 7. Emotion (Washington, D.C.), 7, 388–399. doi:10.1037/1528-3542.7.2.388CrossRefGoogle ScholarPubMed
Durbin, C. E., & Wilson, S. (2012). Convergent validity of and bias in maternal reports of child emotion. Psychological Assessment, 24, 647–660. doi:10.1037/a0026607CrossRefGoogle ScholarPubMed
Egger, H., Ascher, B. H., & Angold, A. (1999). Preschool age psychiatric assessment (PAPA).Google Scholar
Evans, S. C., Bonadio, F. T., Bearman, S. K., Ugueto, A. M., Chorpita, B. F., & Weisz, J. R. (2019). Assessing the irritable and defiant dimensions of youth oppositional behavior using CBCL and YSR items. Journal of Clinical Child and Adolescent Psychology, 49, 804–819. doi:10.1080/15374416.2019.1622119CrossRefGoogle ScholarPubMed
Gagne, J. R., Van Hulle, C. A., Aksan, N., Essex, M. J., & Goldsmith, H. H. (2011a). Deriving childhood temperament measures from emotion-eliciting behavioral episodes: Scale construction and initial validation. Psychological Assessment, 23, 337–353. doi:10.1037/a0021746CrossRefGoogle Scholar
Gagne, J. R., Van Hulle, C. A., Aksan, N., Essex, M. J., & Goldsmith, H. H. (2011b). Deriving childhood temperament measures from emotion-eliciting behavioral episodes: Scale construction and initial validation. Psychological Assessment, 23, 337–353. doi:10.1037/a0021746Google Scholar
Gartstein, M. A., & Marmion, J. (2008). Fear and positive affectivity in infancy: Convergence/discrepancy between parent-report and laboratory-based indicators. Infant Behavior and Development, 31, 227–238. doi:10.1016/j.infbeh.2007.10.012CrossRefGoogle ScholarPubMed
Goldsmith, H. H., & Lemery, K. S. (2000). Linking temperamental fearfulness and anxiety symptoms: A behavior-genetic perspective. Biological Psychiatry, 48, 1199–1209. doi:10.1016/S0006-3223(00)01003-9CrossRefGoogle ScholarPubMed
Goldsmith, H. H., Reilly, J., Lemery, K. S., Longley, S., & Prescott, A. (1995). Laboratory Temperament Assessment Battery: Preschool version.Google Scholar
Goodman, S. H., Rouse, M. H., Connell, A. M., Broth, M. R., Hall, C. M., & Heyward, D. (2011). Maternal depression and child psychopathology: A meta-analytic review. Clinical Child and Family Psychology Review, 14, 1–27. doi:10.1007/s10567-010-0080-1CrossRefGoogle ScholarPubMed
Hayden, E. P., Klein, D. N., & Durbin, C. E. (2005). Parent reports and laboratory assessments of child temperament: A comparison of their associations with risk for depression and externalizing disorders. Journal of Psychopathology and Behavioral Assessment, 27, 89–100. doi:10.1007/s10862-005-5383-zCrossRefGoogle Scholar
Johnson, V. C., Olino, T. M., Klein, D. N., Dyson, M. W., Bufferd, S. J., Durbin, C. E., … Hayden, E. P. (2016). A longitudinal investigation of predictors of the association between age 3 and age 6 behavioural inhibition. Journal of Research in Personality, 63, 51–61. doi:10.1016/j.jrp.2016.04.008CrossRefGoogle ScholarPubMed
Karp, J., Serbin, L. A., Stack, D. M., & Schwartzman, A. E. (2004). An observational measure of children's behavioural style: Evidence supporting a multi-method approach to studying temperament. Infant and Child Development, 13, 135–158. doi:10.1002/icd.346CrossRefGoogle Scholar
Krueger, R. F., & Piasecki, T. M. (2002). Toward a dimensional and psychometrically-informed approach to conceptualizing psychopathology. Behaviour Research and Therapy, 40, 485–499. doi:10.1016/S0005-7967(02)00016-5CrossRefGoogle Scholar
Leibenluft, E. (2011). Severe mood dysregulation, irritability, and the diagnostic boundaries of bipolar disorder in youths. American journal of psychiatry 168(2), 129–142.CrossRefGoogle ScholarPubMed
Leibenluft, E. (2017). Pediatric irritability: A systems neuroscience approach. Trends in Cognitive Sciences, 21, 277–289. doi:10.1016/j.tics.2017.02.002CrossRefGoogle ScholarPubMed
Leibenluft, E., Cohen, P., Gorrindo, T., Brook, J. S., & Pine, D. S. (2006). Chronic versus episodic irritability in youth: A communitybased, longitudinal study of clinical and diagnostic associations. Journal of Child and Adolescent Psychopharmacology, 16(4), 456–466. doi:10.1089/cap.2006.16.456CrossRefGoogle Scholar
Leibenluft, E., & Stoddard, J. (2013). The developmental psychopathology of irritability. Development and Psychopathology, 25, 1473–1487. doi:10.1017/S0954579413000722Google ScholarPubMed
Lengua, L. J., Sadowski, C. A., Friedrich, W. N., & Fisher, J. (2001). Rationally and empirically derived dimensions of children's symptomatology: Expert ratings and confirmatory factor analyses of the CBCL. Journal of Consulting and Clinical Psychology, 69, 683–698. doi:10.1037/0022-006X.69.4.683Google ScholarPubMed
Locke, R. L., Davidson, R. J., Kalin, N. H., & Goldsmith, H. H. (2009). Children's context inappropriate anger and salivary cortisol. Developmental Psychology, 45, 1284–1297. doi:10.1037/a0015975CrossRefGoogle ScholarPubMed
Locke, R. L., Miller, A. L., Seifer, R., & Heinze, J. E. (2015). Context-inappropriate anger, emotion knowledge deficits, and negative social experiences in preschool. Developmental Psychology, 51, 1450–1463. doi:10.1037/a0039528CrossRefGoogle ScholarPubMed
Mackrell, S. V. M., Sheikh, H. I., Kotelnikova, Y., Kryski, K. R., Jordan, P. L., Singh, S. M., & Hayden, E. P. (2014). Child temperament and parental depression predict cortisol reactivity to stress in middle childhood. Journal of Abnormal Psychology, 123, 106–116. doi:10.1037/a0035612CrossRefGoogle ScholarPubMed
Majdandžić, M., & Van Den Boom, D. C. (2007). Multimethod longitudinal assessment of temperament in early childhood. Journal of Personality, 75, 121–168. doi:10.1111/j.1467-6494.2006.00435.xCrossRefGoogle ScholarPubMed
Malhi, G., Bell, E., & Outhred, T. (2019). Getting irritable about irritability? Evidence-Based Mental Health, 22, 93–94. doi:10.1136/ebmental-2019-300101CrossRefGoogle ScholarPubMed
Mick, E., Spencer, T., Wozniak, J., & Biederman, J. (2005). Heterogeneity of irritability in attention-deficit/hyperactivity disorder subjects with and without mood disorders. Biological Psychiatry, 58, 576–582. doi:10.1016/j.biopsych.2005.05.037CrossRefGoogle ScholarPubMed
Moore, A. A., Lapato, D. M., Brotman, M. A., Leibenluft, E., Aggen, S. H., Hettema, J. M., … Roberson-Nay, R. (2019). Heritability, stability, and prevalence of tonic and phasic irritability as indicators of disruptive mood dysregulation disorder. Journal of Child Psychology and Psychiatry and Allied Disciplines, 60, 1032–1041. doi:10.1111/jcpp.13062Google ScholarPubMed
Mulraney, M. A., Melvin, G. A., & Tonge, B. J. (2014). Psychometric properties of the affective reactivity index in Australian adults and adolescents. Psychological Assessment, 26, 148–155. doi:10.1037/a0034891CrossRefGoogle ScholarPubMed
Owens, E. B., Shaw, D. S., & Vondra, J. I. (1998). Relations between infant irritability and maternal responsiveness in low-income families. Infant Behavior and Development, 21, 761–777. doi:10.1016/s0163-6383(98)90043-1CrossRefGoogle Scholar
Pavlova, B., & Uher, R. (2020). Assessment of psychopathology. JAMA Psychiatry, 77, 557. doi:10.1001/jamapsychiatry.2020.0108CrossRefGoogle ScholarPubMed
Riglin, L., Eyre, O., Cooper, M., Collishaw, S., Martin, J., Langley, K., … Thapar, A. (2017). Investigating the genetic underpinnings of early-life irritability. Translational Psychiatry, 7, e1241. doi:10.1038/tp.2017.212CrossRefGoogle ScholarPubMed
Roberson-Nay, R., Leibenluft, E., Brotman, M. A., Myers, J., Larsson, H., Lichtenstein, P., & Kendler, K. S. (2015). Longitudinal stability of genetic and environmental influences on irritability: From childhood to young adulthood. The American Journal of Psychiatry, 172, 657–664. doi:10.1176/appi.ajp.2015.14040509CrossRefGoogle ScholarPubMed
Rothbart, M. K. (1989). Child behavior questionnaire. Eugene, OR: University of Oregon.Google Scholar
Rothbart, M. K., Ahadi, S. A., Hershey, K. L., & Fisher, P. (2001). Investigations of temperament at three to seven years: The children's behavior questionnaire. Child Development, 72, 1394–1408. doi:10.1111/1467-8624.00355CrossRefGoogle ScholarPubMed
Savage, J., Verhulst, B., Copeland, W., Althoff, R. R., Lichtenstein, P., & Roberson-Nay, R. (2015). A genetically informed study of the longitudinal relation between irritability and anxious/depressed symptoms. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 377–384. doi:10.1016/j.jaac.2015.02.010CrossRefGoogle ScholarPubMed
Statistics Canada, (2011) Immigration and diversity: Population projections for Canada and its regions, 2011 to 2036.Google Scholar
Stifter, C. A., Dollar, J. M., & Cipriano, E. A. (2011). Temperament and emotion regulation: The role of autonomic nervous system reactivity. Developmental Psychobiology, 53, 266–279. doi:10.1002/dev.20519CrossRefGoogle ScholarPubMed
Stifter, C. A., Willoughby, M. T., & Towe-Goodman, N. (2008). Agree or agree to disagree? Assessing the convergence between parents and observers on infant temperament. Infant and Child Development, 17, 407–426. doi:10.1002/icd.584CrossRefGoogle ScholarPubMed
Stringaris, A. (2011). Irritability in children and adolescents: A challenge for DSM-5. European Child and Adolescent Psychiatry, 20, 61–66. doi:10.1007/s00787-010-0150-4CrossRefGoogle ScholarPubMed
Stringaris, A., Cohen, P., Pine, D. S., & Leibenluft, E. (2009). Adult outcomes of youth irritability: A 20-year prospective community-based study. American Journal of Psychiatry, 166, 1048–1054. doi:10.1176/appi.ajp.2009.08121849Google ScholarPubMed
Stringaris, A., Goodman, R., Ferdinando, S., Razdan, V., Muhrer, E., Leibenluft, E., & Brotman, M. A. (2012). The affective reactivity Index: A concise irritability scale for clinical and research settings. Journal of Child Psychology and Psychiatry and Allied Disciplines, 53, 1109–1117. doi:10.1111/j.1469-7610.2012.02561.xCrossRefGoogle ScholarPubMed
Stringaris, A., Zavos, H., Leibenluft, E., Maughan, B., & Eley, T. (2012). Adolescent irritability: Phenotypic associations and genetic links With depressed mood. American Journal of Psychiatry, 169, 47–54.CrossRefGoogle ScholarPubMed
Toohey, M. J., & DiGiuseppe, R. (2017). Defining and measuring irritability: Construct clarification and differentiation. Clinical Psychology Review, 53, 93–108. doi:10.1016/j.cpr.2017.01.009CrossRefGoogle ScholarPubMed
Tseng, W. L., Moroney, E., Machlin, L., Roberson-Nay, R., Hettema, J. M., Carney, D., … Brotman, M. A. (2017). Test-retest reliability and validity of a frustration paradigm and irritability measures. Journal of Affective Disorders, 212, 38–45. doi:10.1016/j.jad.2017.01.024CrossRefGoogle ScholarPubMed
Tzelgov, J., & Henik, A. (1991). Suppression situations in psychological research: Definitions, implications, and applications. Psychological Bulletin, 109, 524–536. doi:10.1037/0033-2909.109.3.524CrossRefGoogle Scholar
Vogel, A. C., Jackson, J. J., Barch, D. M., Tillman, R., & Luby, J. L. (2019). Excitability and irritability in preschoolers predicts later psychopathology: The importance of positive and negative emotion dysregulation. Development and Psychopathology, 31, 1067–1083. doi:10.1017/S0954579419000609CrossRefGoogle ScholarPubMed
Wakschlag, L. S., Briggs-Gowan, M. J., Hill, C., Danis, B., Leventhal, B. L., Keenan, K., … Carter, A. S. (2008). Observational assessment of preschool disruptive behavior, part II: Validity of the disruptive behavior diagnostic observation schedule (DB-DOS). Journal of the American Academy of Child and Adolescent Psychiatry, 47, 632–641. doi:10.1097/CHI.0b013e31816c5c10CrossRefGoogle Scholar
Wakschlag, L. S., Choi, S. W., Carter, A. S., Hullsiek, H., Burns, J., McCarthy, K., … Briggs-Gowan, M. J. (2012). Defining the developmental parameters of temper loss in early childhood: Implications for developmental psychopathology. Journal of Child Psychology and Psychiatry and Allied Disciplines, 53, 1099–1108. doi:10.1111/j.1469-7610.2012.02595.xCrossRefGoogle ScholarPubMed
Wakschlag, L. S., Estabrook, R., Petitclerc, A., Henry, D., Burns, J. L., Perlman, S. B., … Briggs-Gowan, M. L. (2015). Clinical implications of a dimensional approach: The normal:abnormal spectrum of early irritability. Journal of the American Academy of Child and Adolescent Psychiatry, 54, 626–634. doi:10.1016/j.jaac.2015.05.016CrossRefGoogle ScholarPubMed
Wakschlag, L. S., Hill, C., Carter, A. S., Danis, B., Egger, H. L., Keenan, K., … Briggs-Gowan, M. J. (2008). Observational assessment of preschool disruptive behavior, part I: Reliability of the disruptive behavior diagnostic observation schedule (DB-DOS). Journal of the American Academy of Child and Adolescent Psychiatry, 47, 622–631. doi:10.1097/CHI.0b013e31816c5bdbCrossRefGoogle Scholar
Wiggins, J. L., Mitchell, C., Stringaris, A., & Leibenluft, E. (2014). Developmental trajectories of irritability and bidirectional associations with maternal depression. Journal of the American Academy of Child and Adolescent Psychiatry, 53, 1191–1205.e4. doi:10.1016/j.jaac.2014.08.005CrossRefGoogle ScholarPubMed