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Child maltreatment, callous–unemotional traits, and defensive responding in high-risk children: An investigation of emotion-modulated startle response

Published online by Cambridge University Press:  04 November 2015

Melissa N. Dackis*
Affiliation:
University of Rochester Mt. Hope Family Center CBT/DBT Associates
Fred A. Rogosch*
Affiliation:
University of Rochester Mt. Hope Family Center
Dante Cicchetti
Affiliation:
University of Rochester Mt. Hope Family Center University of Minnesota Institute of Child Development
*
Address correspondence and reprint requests to: Melissa Dackis or Fred A. Rogosch, Mt. Hope Family Center, 187 Edinburgh Street, Rochester, NY 14608; E-mail: [email protected] or [email protected].
Address correspondence and reprint requests to: Melissa Dackis or Fred A. Rogosch, Mt. Hope Family Center, 187 Edinburgh Street, Rochester, NY 14608; E-mail: [email protected] or [email protected].

Abstract

Child maltreatment is associated with disruptions in physiological arousal, emotion regulation, and defensive responses to cues of threat and distress, as well as increased risk for callous unemotional (CU) traits and externalizing behavior. Developmental models of CU traits have focused on biological and genetic risk factors that contribute to hypoarousal and antisocial behavior, but have focused less on environmental influences (Blair, 2004; Daversa, 2010; Hare, Frazell, & Cox, 1978; Krueger, 2000; Shirtcliff et al., 2009; Viding, Fontaine, & McCrory, 2012). The aim of the present investigation was to measure the independent and combined effects of child maltreatment and high CU traits on emotion-modulated startle response in children. Participants consisted of 132 low-income maltreated (n = 60) and nonmaltreated (n = 72) children between 8 and 12 years old who attended a summer camp program. Acoustic startle response (ASR) was elicited in response to a 110-dB 50-ms probe while children viewed a slideshow of pleasant, neutral, and unpleasant IAPS images. Maltreatment status was assessed through examination of Department of Human Services records. CU traits were measured using counselor reports from the Inventory of Callous and Unemotional Traits (Frick, 2004), and conduct problems were measured using counselor and child self-report. We found no significant differences in emotion-modulated startle in the overall sample. However, significant differences in ASR by maltreatment status, maltreatment subtype, and level of CU traits were apparent. Results indicated differential physiological responses for maltreated and nonmaltreated children based on CU traits, including a pathway of hypoarousal for nonmaltreated/high CU children that differed markedly from a more normative physiological trajectory for maltreated/high CU children. Further, we found heightened ASR for emotionally and physically neglected children with high CU and elevated antisocial behavior in these children. Results provide further support for differential trajectories by which experience and biology may influence the development of antisocial behavior in youth and highlight potential avenues for intervention.

Type
Regular Articles
Copyright
Copyright © Cambridge University Press 2015 

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References

Achenbach, T. (1991). Manual for the Teacher Report Form and 1991 profile. Burlington, VT: University of Vermont, Department of Psychiatry.Google Scholar
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.Google Scholar
Anastassiou-Hadjicharalambous, X., & Warden, D. (2008). Physiologically-indexed and self-perceived affective empathy in conduct-disordered children high and low on callous-unemotional traits. Child Psychiatry and Human Development, 39, 503517.Google Scholar
Armbruster, D., Mueller, A., Strobel, A., Kirschbaum, C., Lesch, K., & Brocke, B. (2010). Influence of tryptophan hydroxylase 2 gene variation and sex on the startle response in children, young adults, and older adults. Biological Psychology, 83, 214221.Google Scholar
Balaban, M. T. (1995). Affective influences on startle in five-month-old infants: Reactions to facial expressions of emotion. Child Development, 66, 2836.Google Scholar
Balaban, M. T., & Berg, K. W. (2007). Measuring the electromyographic startle response: Developmental issues and findings. In Schmidt, L. A. & Segalowitz, S. J. (Eds.), Developmental psychophysiology: Theory, systems, and methods (pp. 257286). Cambridge: Cambridge University Press.Google Scholar
Barnett, D., Manly, J. T., & Cicchetti, D. (1993). Defining child maltreatment: The interface between policy and research. In Cicchetti, D. & Toth, S. L. (Eds.), Child abuse, child development, and social policy (pp. 774). Norwood, NJ: Ablex.Google Scholar
Beers, S. R., & De Bellis, M. D. (2002). Outcomes of child abuse. Neurosurgery Clinics of North America, 13, 235241.Google Scholar
Bernstein, D. P., Stein, J. A., & Handelsman, L. (1998). Predicting personality pathology among adult patients with substance use disorders: Effects of childhood maltreatment. Addictive Behaviors, 23, 855868.CrossRefGoogle ScholarPubMed
Blair, R. J. R. (2004). The roles of orbital frontal cortex in the modulation of antisocial behavior. Brain and Cognition, 55, 198208.Google Scholar
Blair, R. J. R., Peschardt, K. S., Budhani, S., Mitchell, D. G. V., & Pine, D. S. (2006). The development of psychopathy. Journal of Child Psychology and Psychiatry, 47, 262275.Google Scholar
Blumenthal, T. D., Cuthbert, B. N., Filion, D. L., Hackley, S., Lipp, O. V., & Boxtel, A. V. (2005). Committee report: Guidelines for human startle eyeblink electromyographic studies. Psychophysiology, 42, 115.Google Scholar
Bolger, K. E., Patterson, C. J., & Kupersmidt, J. B. (1998). Peer relationships and self-esteem among children who have been maltreated. Child Development, 69, 11711197.Google Scholar
Bradley, M. M., Codispoti, M., & Lang, P. J. (2006). A multiprocess account of startle modulation during affective perception. Psychophysiology, 43, 486497.Google Scholar
Bradley, M. M., Cuthbert, B. N., & Lang, P. J. (1993). Pictures as prepulse: Attention and emotion in startle modification. Psychophysiology, 30, 541545.CrossRefGoogle ScholarPubMed
Briere, J., & Jordan, C. E. (2009). The relationship between childhood maltreatment, moderating variables, and adult psychological difficulties in women: An overview. Trauma, Violence, and Abuse: A Review Journal, 10, 375388.Google Scholar
Brinkmeyer, M. Y., & Eyberg, S. M. (2003). Parent-child interaction therapy for oppositional children. In Kazdin, A. E. & Weisz, J. R. (Eds.), Evidence-based psychotherapies for children and adolescents (pp. 204223). New York: Guilford Press.Google Scholar
Carpenter, L. L., Shattuck, T. T., Tyrka, A. R., Geracioti, T. D., & Price, L. H. (2011). Effect of childhood physical abuse on cortisol stress response. Psychopharmacology, 214, 367375.Google Scholar
Carrion, V. G., & Wong, S. S. (2012). Can traumatic stress alter the brain? Understanding the implications of early trauma on brain development and learning. Journal of Adolescent Health, 51(Suppl. 2), S23S38.Google Scholar
Cicchetti, D. (2013). Annual Research Review: Resilient functioning in maltreated children—Past, present, and future perspectives. Journal of Child Psychology and Psychiatry, 54, 402422.CrossRefGoogle ScholarPubMed
Cicchetti, D., & Blender, J. A. (2006). A multiple-levels-of-analysis perspective on resilience. Annals of the New York Academy of Sciences, 1094, 248258.CrossRefGoogle ScholarPubMed
Cicchetti, D., & Manly, J. T. (1990). A personal perspective on conducting research with maltreating families: Problems and solutions. In Brody, G. & Sigel, I. (Eds.), Methods of family research: Families at risk (Vol. 2, pp. 87133). Hillsdale, NJ: Erlbaum.Google Scholar
Cicchetti, D., & Ng, R. (2014). Emotional development in maltreated children. In Lagatutta, K. H. (Ed.), Children and emotion: New insights into developmental affective science (Vol. 26, pp. 2941). Basel: Karger.Google Scholar
Cicchetti, D., & Rogosch, F. A. (2001a). Diverse patterns of neuroendocrine activity in maltreated children. Development and Psychopathology, 13, 677693.Google Scholar
Cicchetti, D., & Rogosch, F. A. (2001b). The impact of child maltreatment and psychopathology upon neuroendocrine functioning. Development and Psychopathology, 13, 783804.CrossRefGoogle ScholarPubMed
Cicchetti, D., & Toth, S. L. (2015). Child maltreatment and developmental psychopathology: A multilevel perspective. In Lamb, M. & Garcia Coll, C. (Eds.), Handbook of child psychology and developmental science: Vol. 3. Socioemotional process (7th ed.). New York: Wiley.Google Scholar
Cicchetti, D., Toth, S. L., & Manly, J. T. (2003). Maternal Maltreatment Interview. Unpublished manuscript, Rochester, NY.Google Scholar
Cicchetti, D., & Valentino, K. (2006). An ecological transactional perspective on child maltreatment: Failure of the average expectable environment and its influence upon child development. In Cicchetti, D. & Cohen, D. J. (Eds.), Developmental psychopathology: Vol. 3. Risk, disorder, and adaptation (2nd ed., pp. 129201). Hoboken, NJ: Wiley.Google Scholar
Cohen, J. A., Mannarino, A. P., & Deblinger, E. (2006). Treating trauma and traumatic grief in children and adolescents. New York: Guilford Press.Google Scholar
Cook, E. W., Hawk, L. W., Hawk, T. M., & Hummer, K. (1995). Affective modulation of startle in children. Psychophysiology, 32, S25.Google Scholar
Dadds, M. R., Cauchi, A. J., Wimalaweera, S., Hawes, D. J., & Brennan, J. (2012). Outcomes, moderators, and mediators of empathic–emotion recognition training for complex conduct problems in childhood. Psychiatry Research, 199, 201207.Google Scholar
Dadds, M. R., Mullins, M. J., McAllister, R. A., & Atkinson, E. R. (2002). Attributions, affect, and behavior in abuse-risk mothers: A laboratory study. Child Abuse & Neglect, 27, 2145.Google Scholar
Dadds, M. R., Perry, Y., Hawes, D. J., Merz, S., Riddell, A. C., Haines, D. J., et al. (2006). Attention to the eyes reverses fear-recognition deficits in child psychopathy. British Journal of Psychiatry, 189, 280281.Google Scholar
Dahl, R. E., & Spear, L. P. (2004). Adolescent brain development: Vulnerabilities and opportunities (Vol. 1021). New York: New York Academy of Sciences.Google Scholar
Dannlowski, U., Stuhrmann, A., Beutelmann, V., Zwanzger, P., Lenzen, T., & Grotegerd, D., et al. (2012). Limbic scars: Long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging. Biological Psychiatry, 71, 286293.Google Scholar
Daversa, M. T. (2010). Early environmental predictors of the affective and interpersonal constructs of psychopathy. International Journal of Offender Therapy and Comparative Criminology, 54, 621.Google Scholar
Davis, M. (1989). Neural systems involved in fear-potentiated startle. Annals of the New York Academy of Sciences, 563, 165183.Google Scholar
Davis, M., Falls, W. A., Campeau, S., & Kim, M. (1993). Fear-potentiated startle: A neural and pharmacological analysis. Behavioural Brain Research, 58, 175198.Google Scholar
Davis, M., & Whalen, P. J. (2001). The amygdala: Vigilance and emotion. Molecular Psychiatry, 6, 1334.Google Scholar
De Bellis, M. D., Chrousos, G. P., Dorn, L. D., Burke, L., Helmers, K., Kling, M. A., et al. (1994). Hypothalamic-pituitary-adrenal axis dysregulation in sexually abused girls. Journal of Clinical Endocrinology & Metabolism, 78, 249255.Google Scholar
De Bellis, M. D., Keshavan, M. S., Clark, D. B., Case, B. J., Giedd, J. N., Boring, A. M., et al. (1999). Developmental traumatology: Part II. Brain development. Biological Psychiatry, 45, 12711284.Google Scholar
DePrince, A. P., Weinzierl, K. M., & Combs, M. D. (2009). Executive function performance and trauma exposure in a community sample of children. Child Abuse & Neglect, 33, 353361.CrossRefGoogle Scholar
de Wied, M., van Boxten, A., Matthys, W., & Meeus, W. (2012). Verbal, facial and autonomic responses to empathy-eliciting film clips by disruptive male adolescents with high versus low callous-unemotional traits. Journal of Abnormal Child Psychology, 40, 211223.CrossRefGoogle ScholarPubMed
Dichter, G. S., Tomarken, A. J., & Baucom, B. R. (2002). Startle modulation before, during and after exposure to emotional stimuli. International Journal of Psychophysiology, 43, 191196.CrossRefGoogle ScholarPubMed
Dodge, K. A., Pettit, G. S., & Bates, J. E. (1990). Mechanisms in the cycle of violence. Science, 250, 16781683.Google Scholar
Doom, J. R., Cicchetti, D., & Rogosch, F. A. (2014). Longitudinal patterns of cortisol regulation differ in maltreated and nonmaltreated children. Journal of the American Academy of Child & Adolescent Psychiatry, 53, 12061215.Google Scholar
Dubowitz, H., Pitts, S. C., Litrownik, A. J., Cox, C. E., Runyan, D., & Black, M. M. (2005). Defining child neglect based on child protective services data. Child Abuse & Neglect, 29, 493511.CrossRefGoogle ScholarPubMed
Dvir, Y., Ford, J. D., Hill, M., & Frazier, J. A. (2014). Childhood maltreatment, emotional dysregulation, and psychiatric comorbidities. Harvard Review of Psychiatry, 22, 149161.CrossRefGoogle ScholarPubMed
Elliot, D. S., Huizinga, D., & Ageton, S. (1985). Explaining delinquency and drug use. Beverly Hills, CA: Sage.Google Scholar
Enebrink, P., Anderson, H., & Langstrom, N. (2005). Callous-unemotional traits are associated with clinical severity in referred boys with conduct problems. Nordic Journal of Psychiatry, 59, 431440.Google Scholar
English, D. J., Upadhyaya, M. P., Litrownik, A. J., Marshall, J. M., Runyan, D. K., Graham, J. C., et al. (2005). Maltreatment's wake: The relationship of maltreatment dimensions to child outcomes. Child Abuse & Neglect, 29, 597619.CrossRefGoogle ScholarPubMed
Essau, C. A., Sasagawa, S., & Frick, P. J. (2006). Callous-unemotional traits in community sample of adolescents. Assessment, 13, 454469.Google Scholar
Ezpeleta, L., Osa, N. D. L., Granero, R., Penelo, E., & Domènech, J. M. (2013). Inventory of callous-unemotional traits in a community sample of preschoolers. Journal of Clinical Child & Adolescent Psychology, 42, 91105.Google Scholar
Fairchild, G., Stobbe, Y., van Goozen, S. H., Calder, A. J., & Goodyer, I. M. (2010). Facial expression recognition, fear conditioning, and startle modulation in female subjects with conduct disorder. Biological Psychiatry, 68, 272279.Google Scholar
Fairchild, G., van Goozen, S. H., Stollery, S. J., & Goodyer, I. M. (2008). Fear conditioning and affective modulation of the startle reflex in male adolescents with early-onset or adolescence-onset conduct disorder and healthy control subjects. Biological Psychiatry, 63, 279285.Google Scholar
Fanti, K. A., Panayiotou, G., Lazarou, C., Michael, R., & Georgiou, G. (2015). The better of two evils? Evidence that children exhibiting continuous conduct problems high or low on callous-unemotional traits score on opposite directions on physiological and behavioral measures of fear. Development and Psychopathology. Advance online publication.Google Scholar
Finger, E. C., Marsh, A. A., Mitchell, D. G., Reid, M. E., Sims, C., Budhani, S., et al. (2008). Abnormal ventromedial prefrontal cortex function in children with psychopathic traits during reversal learning. Archives of General Psychiatry, 65, 586594.Google Scholar
Frick, P. J. (2004). Inventory of Callous-Unemotional Traits. Unpublished manuscript, University of New Orleans.Google Scholar
Frick, P. J. (2012). Developmental pathways to conduct disorder: Implications for future directions in research, assessment, and treatment. Journal of Clinical Child & Adolescent Psychology, 41, 378389.Google Scholar
Frick, P. J., Cornell, A. H., Bodin, S. D., Dane, H. E., Barry, C. T., & Loney, B. R. (2003). Callous-unemotional traits and developmental pathways to severe conduct problems. Developmental Psychology, 39, 246260.Google Scholar
Frick, P. J., & Dickens, C. (2006). Current perspectives on conduct disorder. Current Psychiatry Reports, 8, 5972.Google Scholar
Frick, P. J., & Moffitt, T. E. (2010). A proposal to the DSM-V childhood disorders and the ADHD and disruptive behavior disorders work groups to include a specifier to the diagnosis of conduct disorder based on the presence of callous-unemotional traits. Washington, DC: APA.Google Scholar
Frick, P. J., Stickle, T. R., Dandreaux, D. M., Farrell, J. M., & Kimonis, E. R. (2005). Callous–unemotional traits in predicting the severity and stability of conduct problems and delinquency. Journal of Abnormal Child Psychology, 33, 471487.Google Scholar
Frick, P. J., & White, S. F. (2008). Research Review: The importance of callous-unemotional traits for developmental models of aggressive and antisocial behavior. Journal of Child Psychology and Psychiatry, 49, 359375.Google Scholar
Gostisha, A. J., Vitacco, M. J., Dismukes, A. R., Brieman, C., Merz, J., & Shirtcliff, E. A. (2014). Beyond physiological hypoarousal: The role of life stress and callous-unemotional traits in incarcerated adolescent males. Hormones & Behavior, 65, 469479.Google Scholar
Grasso, D. J., & Simons, R. F. (2012). Electrophysiological responses to threat in youth with and without posttraumatic stress disorder. Biological Psychiatry, 90, 8896.Google Scholar
Grillon, C., Morgan, C. A., Davis, M., & Southwick, S. M. (1998a). Effect of darkness on acoustic startle in Vietnam veterans with PTSD. American Journal of Psychiatry, 155, 812817.Google ScholarPubMed
Grillon, C., Morgan, C. A., Davis, M., & Southwick, S. M. (1998b). Effects of experimental context and explicit threat cues on acoustic startle in Vietnam veterans with posttraumatic stress disorder. Biological Psychiatry, 44, 10271036.Google Scholar
Gunnar, M. R., & Vazquez, D. M. (2001). Low cortisol and a flattening of expected daytime rhythm: Potential indices of risk in human development. Development and Psychopathology, 13, 515538.Google Scholar
Hajcak, G., & Dennis, T. A. (2009). Brain potentials during affective picture viewing. Biological Psychiatry, 80, 333338.Google Scholar
Hare, R. D., Frazell, J., & Cox, J. (1978). Psychopathy and physiological responses to threat of an aversive stimulus. Psychophysiology, 15, 165172.Google Scholar
Hart, H., & Rubia, K. (2012). Neuroimaging of child abuse: A critical review. Frontiers in Human Neuroscience, 19, 6.Google Scholar
Hart, J., Gunnar, M., & Cicchetti, D. (1995). Salivary cortisol in maltreated children: Evidence of relations between neuroendocrine activity and social competence. Development and Psychopathology, 7, 1126.Google Scholar
Hawes, S. W., Byrd, A. L., Henderson, C. E., Gazda, R. L., Burke, J. D., Loeber, R., et al. (2014). Refining the parent-reported Inventory of Callous-Unemotional Traits in boys with conduct problems. Psychological Assessment, 26, 256.Google Scholar
Heim, C., & Nemeroff, C. B. (2001). The role of childhood trauma in the neurobiology of mood and anxiety disorders: Preclinical and clinical studies. Biological Psychiatry, 49, 10231039.Google Scholar
Herman, J. P., Ostrander, M. M., Mueller, K. K., & Figueiredo, H. (2005). Limbic system mechanisms of stress regulation: Hypothalamo-pituitary-adrenocrotical axis. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 29, 12011213.Google Scholar
Jones, A. P., Laurens, K. R., Herba, C. M., Barker, G. J., & Viding, E. (2009). Amygdala hypoactivity to fearful faces in boys with conduct problems and callous-unemotional traits. American Journal of Psychiatry, 166, 95102.Google Scholar
Kaplow, J. B., & Widom, C. S. (2007). Age of onset of child maltreatment predicts long-term mental health outcomes. Journal of Abnormal Psychology, 116, 176187.Google Scholar
Kaufman, J., Birmaher, B., Perel, J., Dahl, R. E., Moreci, P., Nelson, B., et al. (1997). The corticotropin-releasing hormone challenge in depressed abuse, depressed nonabused, and normal control children. Biological Psychiatry, 42, 669679.Google Scholar
Keiley, M. K., Howe, T. R., Dodge, K. A., Bates, J. E., & Pettit, G. S. (2001). The timing of child physical maltreatment: A cross-domain growth analysis of impact on adolescent externalizing and internalizing problems. Development and Psychopathology, 13, 891912.Google Scholar
Kim, J., & Cicchetti, D. (2010). Longitudinal pathways linking child maltreatment, emotion regulation, peer relations, and psychopathology. Journal of Child Psychology and Psychiatry, 51, 706716.Google Scholar
Kimonis, E. R., Fanti, K. A., Frick, P. J., Moffitt, T. E., Essau, C., Bijttebier, P., et al. (2014). Using self-reported callous-unemotional traits to cross-nationally assess the DSM-5 “With Limited Prosocial Emotions” specifier. Journal of Child Psychology and Psychiatry. Advance online publication.Google Scholar
Kimonis, E. R., Fanti, K. A., Isoma, Z., & Donoghue, K. (2013). Maltreatment profiles among incarcerated boys with callous-unemotional traits. Child Maltreatment, 18, 108121.Google Scholar
Kimonis, E. R., Frick, P. J., Fazekas, H., & Loney, B. R. (2006). Psychopathy, aggression, and the emotional processing of emotional stimuli in non-referred girls and boys. Behavioral Sciences and the Law, 24, 2137.Google Scholar
Kimonis, E. R., Frick, P. J., Munoz, L. C., & Aucoin, K. J. (2007). Can a laboratory measure of emotional processing enhance the statistical prediction of aggression and delinquency in detained adolescents with callous-unemotional traits? Journal of Abnormal Child Psychology, 35, 773785.Google Scholar
Kimonis, E. R., Frick, P. J., Skeem, J. L., Marsee, M. M., Cruise, K., Munoz, L. C., et al. (2008). Assessing callous-unemotional traits in adolescent offenders: Validation of the Inventory of Callous-Unemotional Traits. International Journal of Law and Psychiatry, 31, 241252.Google Scholar
Klorman, R., Cicchetti, D., Thatcher, J. E., & Ison, J. R. (2003). Acoustic startle in maltreated children. Journal of Abnormal Child Psychology, 31, 359370.Google Scholar
Koch, M. (1999). The neurobiology of startle. Progress in Neurobiology, 59, 107128.Google Scholar
Krueger, R. F. (2000). Phenotypic, genetic, and nonshared environmental parallels in the structure of personality: A view from the Multidimensional Personality Questionnaire. Journal of Personality and Social Psychology, 79, 10571067.Google Scholar
Kumsta, R., Sonuga-Barke, E., & Rutter, M. (2012). Adolescent callous-unemotional traits and conduct disorder in adoptees exposed to severe early deprivation. British Journal of Psychiatry, 200, 197201.Google Scholar
Landis, C., & Hunt, W. A. (1939). The startle pattern. New York: Rinehart.Google Scholar
Lang, P. J. (1980). Behavioral treatment and bio-behavioral assessment: Computer applications. In Sidowski, J. B., Johnson, J. H., & Williams, E. A.. (Eds.), Technology in mental health care delivery systems (pp. 119137). Norwood, NJ: Ablex.Google Scholar
Lang, P. J. (1995). The emotion probe: Studies of motivation and attention. American Psychologist, 50, 372.Google Scholar
Lang, P. J., & Bradley, M. M. (2010). Emotion and the motivated brain. Biological Psychiatry, 84, 437450.Google Scholar
Lang, P. J., Bradley, M. M., & Cuthbert, B. N. (1990). Startle reflex modification: Emotion or attention? Psychophysiology, 27, 513522.Google Scholar
Lang, P. J., Bradley, M. M., & Cuthbert, B. N. (1997). Motivated attention: Affect, activation and action. In Lang, P. J., Simons, R. F., & Balaban, M. F. (Eds.), Attention and orienting: Sensory and motivational processes (pp. 97135). Hillside, NJ: Erlbaum.Google Scholar
Lang, P. J., Bradley, M. M., & Cuthbert, B. N. (2008). International Affective Picture System (IAPS): Affective ratings of pictures and instruction manual (Technical Report A-8). Gainesville, FL: University of Florida.Google Scholar
Lang, P. J., & Davis, M. (2006). Emotion, motivation, and the brain: Reflex foundations in animal and human research. Progress in Brain Research, 156, 329.Google Scholar
Lang, S., Klinteberg, B., & Alm, P. (2002). Adult psychopathy and violent behavior in males with early neglect and abuse. Acta Psychiatrica Scandinavica, 412, 93100.Google Scholar
LeDoux, J. E. (1990). Information flow from sensation to emotion plasticity in the neural computation of stimulus values. In Gabriel, M. & Moore, J. (Eds.), Learning and computational neuroscience: Foundations of adaptive networks (pp. 352). Cambridge, MA: Bradford Books/MIT Press.Google Scholar
LeDoux, J. E. (2000). Emotion circuits in the brain. Annual Review of Neuroscience, 23, 155184.Google Scholar
LeDoux, J. E., Iwata, J., Cicchetti, P., & Reis, D. J. (1988). Differential projection of the central amygdaloid nucleus mediation autonomic and behavioral correlates of conditioned fear. Journal of Neuroscience, 8, 25172529.Google Scholar
Lee, Y., Lopez, D., Meloni, E., & Davis, M. (1996). A primary acoustic startle pathway: Obligatory role of cochlear root neurons and the nucleus reticularis pontis caudalis. Journal of Neuroscience, 16, 37753789.Google Scholar
Lipschitz, D. S., Mayes, L. M., Rasmusson, A. M., Anyan, W., Billingslea, E., & Gueorguieva, R., et al. (2005). Baseline and modulated acoustic startle responses in adolescent girls with posttraumatic stress disorder. Journal of the American Academy of Child Psychiatry, 44, 807814.CrossRefGoogle ScholarPubMed
Loeber, R., Farrington, D. P., Stouthamer-Loeber, M., & Van Kammen, W. B. (1998). Antisocial behavior and mental health problems: Explanatory factors in childhood and adolescence. New York: Psychology Press.Google Scholar
Loeber, R., Stouthamer-Loeber, M., Van Kammen, W. B., & Farrington, D. (1989). Development of a new measure of self-reported antisocial behavior for young children: Prevalence and reliability. In Klein, M. W. (Ed.), Cross-national research in self-reported crime and delinquency (pp. 203225). New York: Kluwer Academic.Google Scholar
Manly, J. T. (2005). Advances in research definitions of child maltreatment. Child Abuse & Neglect, 29, 425439.Google Scholar
Marsh, A. A., Finger, E. C., Mitchell, D. G., Reid, M. E., Sims, C., Kossom, D. S., et al. (2008). Reduced amygdala response to fearful expressions in children and adolescents with callous-unemotional traits and disruptive behavior disorders. American Journal of Psychiatry, 165, 712720.Google Scholar
Mathews, A., & MacLeod, C. (1994). Cognitive approaches to emotion and emotional disorders. Annual Review of Psychology, 45, 2550.Google Scholar
Maughan, A., & Cicchetti, D. (2002). The impact of child maltreatment and interadult violence on children's emotion regulation abilities. Child Development, 73, 15251542.Google Scholar
McCrory, E., & Viding, E. (2010). The neurobiology of maltreatment and adolescent violence. Lancet, 29, 18561857.Google Scholar
McManis, M. H., Bradley, M. M., Berg, K., Cuthbert, B. N., & Lang, P. J. (2001). Emotional reactions in children: Verbal, physiological and behavioral responses to affective pictures. Psychophysiology, 38, 222231.CrossRefGoogle ScholarPubMed
McManis, M. H., Bradley, M. M., Cuthbert, B., & Lang, P. J. (1995). Kids have feelings too: Children's physiological response to affective pictures. Psychophysiology, 33, S53.Google Scholar
Mehta, M. A., Golembo, N. I., Nosarti, C., Colvert, E., Mota, A., Williams, S. C., et al. (2009). Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: The English and Romanian adoptees study pilot. Journal of Child Psychology and Psychiatry, 50, 943951.Google Scholar
Mezzacappa, E., Kindlon, D., & Earls, F. (2001). Child abuse and performance task assessments of executive functions in boys. Journal of Child Psychology & Psychiatry, 42, 10411048.Google Scholar
Miller, G. E., Chen, E., & Zhou, E. S. (2007). If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychological Bulletin, 133, 2545.Google Scholar
Miller, L. P. R., & Azar, S. T. (1996). The pervasiveness of maladaptive attributions in mothers at-risk for child abuse. Family Violence & Sexual Assault Bulletin, 12, 3137.Google Scholar
Monk, C. S., Nelson, E. E., Woldehawariat, G., Montgomery, L. A., Zarahn, E., McClure, E. B., et al. (2004). Experience-dependent plasticity for attention to threat: Behavioral and neurophysiological evidence in humans. Biological Psychiatry, 56, 607610.Google Scholar
Montes, M., De Paul, J., & Milner, J. S. (2001). Evaluations, attributions, affect, and disciplinary choices in mothers at high and low risk for child physical abuse. Child Abuse & Neglect, 25, 10151036.Google Scholar
Morgan, C. A. III, Grillon, C., Southwick, S. M., Davis, M., & Charney, D. S. (1995). Fear-potentiated startle in posttraumatic stress disorder. Biological Psychiatry, 38, 378385.Google Scholar
Morgan, C. A. III, Grillon, C., Southwick, S. M., Nagy, L. M., Davis, M., & Krystal, J. H., et al. (1995). Yohimbine facilitated acoustic startle in combat veterans with post-traumatic stress disorder. Psychopharmacology, 117, 466471.Google Scholar
Obradović, J., Pardini, D., Long, J. D., & Loeber, . (2007). Measuring interpersonal callousness in boys from childhood to adolescence: An examination of longitudinal invariance and temporal stability. Journal of Clinical Child and Adolescent Psychology, 36, 276292.Google Scholar
Pardini, D. A., & Fite, P. J. (2010). Symptoms of conduct disorder, oppositional defiant disorder, attention-deficit/hyperactivity disorder, and callous-unemotional traits as unique predictors of psychosocial maladjustment in boys: Advancing an evidence base for DSM-V. Journal of the American Academy of Child & Adolescent Psychiatry, 49, 11341144.Google ScholarPubMed
Pardini, D. A., Lochman, J. E., & Frick, P. J. (2003). Callous/unemotional traits and social–cognitive processes in adjudicated youths. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 364371.Google Scholar
Patrick, C. J. (1994). Emotion and psychopathy: Startling new insights. Psychophysiology, 31, 319330.Google Scholar
Patton, G. C., & Viner, R. (2007). Pubertal transitions in health. Lancet, 369, 11301139.Google Scholar
Pollak, S. D., Cicchetti, D., Hornung, K., & Reed, A. (2000). Recognizing emotion in faces: Developmental effects of child abuse and neglect. Developmental Psychology, 36, 679688.Google Scholar
Pollak, S. D., Cicchetti, D., Klorman, R., & Brumaghim, J. (1997). Cognitive brain event-related potentials and emotion processing in maltreated children. Child Development, 68, 773787.Google Scholar
Pollak, S. D., & Kistler, D. J. (2002). Early experience is associated with the development of categorical representations for facial expressions of emotion. Proceedings of the National Academy of Sciences, 99, 90729076.Google Scholar
Pollak, S. D., Klorman, R., Thatcher, J. E., & Cicchetti, D. (2001). P3b reflects maltreatment children's reactions to facial displays of emotion. Psychophysiology, 38, 267274.Google Scholar
Pollak, S. D., Nelson, C. A., Schlaak, M. F., Roeber, B. J., Wewerka, S. S., Wiik, K. L., et al. (2010). Neurodevelopmental effects of early deprivation in postinstitutionalized children. Child Development, 81, 224236.Google Scholar
Pollak, S. D., & Sinha, P. (2002). Effects of early experience on children's recognition of facial displays of emotion. Developmental Psychology, 38, 784791.Google Scholar
Quevedo, K. M., Benning, S. D., Gunnar, M. R., & Dahl, R. E. (2009). The onset of puberty: Effects on the psychophysiology of defense and appetitive motivation. Development and Psychopathology, 21, 2745.Google Scholar
Quevedo, K. M., Smith, T., Donzella, B., Schunk, E., & Gunnar, M. (2010). The startle response: Developmental effects and a paradigm for children and adults. Developmental Psychobiology, 52, 7889.Google Scholar
Raine, A. (2002). Biosocial studies of antisocial and violent behavior in children and adults: A review. Journal of Abnormal Child Psychology, 30, 311326.Google Scholar
Rieder, C., & Cicchetti, D. (1989). Organizational perspective on cognitive control functioning and cognitive–affective balance in maltreated children. Developmental Psychology, 25, 382393.Google Scholar
Risbrough, V. (2009). Behavioral correlates of anxiety. In Stein, M. B. & Steckler, T. (Eds.), Behavioral neurobiology of anxiety and its treatment: Current topics in behavioral neurosciences (pp. 205228). Berlin: Springer–Verlag Heidelberg.Google Scholar
Rogosch, F. A., & Cicchetti, D. (2005). Child maltreatment, attention networks, and potential precursors to borderline personality disorder. Development and Psychopathology, 17, 10711089.Google Scholar
Rogosch, F. A., Oshri, A., & Cicchetti, D. (2010). From child maltreatment to adolescent cannabis abuse and dependence: A developmental cascade model. Development and Psychopathology, 22, 883897.Google Scholar
Roose, A., Bijttebier, P., Decoene, S., Claes, L., & Frick, P. J. (2010). Assessing the affective features of psychopathy in adolescence: A further validation of the inventory of callous and unemotional traits. Assessment, 17, 4457.Google Scholar
Rowe, R., Maughan, B., Moran, P., Ford, T., Briskman, J., & Goodman, R. (2010). The role of callous and unemotional traits in the diagnosis of conduct disorder. Journal of Child Psychiatry and Psychology, 51, 688695.Google Scholar
Sedlak, A. J., Mettenburg, J., Basena, M., Petta, I., McPherson, K., Greene, A., et al. (2010). Fourth National Incidence Study of Child Abuse and Neglect (NIS–4): Report to Congress, executive summary. Washington, DC: US Department of Health and Human Services, Administration for Children and Families.Google Scholar
Shackman, J. E., Shackman, A. J., & Pollak, S. D. (2007). Physical abuse amplifies attention to threat and increases anxiety in children. American Psychological Association, 7, 838852.Google Scholar
Shields, A., & Cicchetti, D. (2001). Parental maltreatment and emotion dysregulation as risk factors for bullying and victimization in middle childhood. Journal of Clinical Child Psychology, 30, 349363.Google Scholar
Shipman, K., Zeman, J., Penza, S., & Champion, K. (2000). Emotion management skills in sexually maltreated and nonmaltreated girls: A developmental psychopathology perspective. Development and Psychopathology, 12, 4762.Google Scholar
Shirtcliff, E. A., Vitacco, M. J., Graf, A. R., Gostisha, A. J., Merz, J. L., & Zahn-Waxler, C. (2009). Neurobiology of empathy and callousness: Implications for the development of antisocial behavior. Behavioral Sciences and the Law, 27, 137171.Google Scholar
Smith, C. A., & Thornberry, T. (1995). The relationship between child maltreatment and adolescent involvement in delinquency. Criminology, 33, 451481.Google Scholar
Solomon, B., DeCiccio, J. M., & Dennis, T. A. (2012). Emotional picture processing in children: nERP study. Developmental Cognitive Neuroscience, 2, 110119.Google Scholar
Sterzer, P., Stadler, C., Krebs, A., Kleinschmidt, A., & Poustka, F. (2005). Abnormal neural responses to emotional visual stimuli in adolescents with conduct disorder. Biological Psychiatry, 57, 715.Google Scholar
Susman, E. J. (2006). Psychobiology of persistent antisocial behavior: Stress, early vulnerabilities and the attenuation hypothesis. Neuroscience & Biobehavioral Reviews, 30, 376389.Google Scholar
Syngelaki, E. M., Fairchild, G., Moore, S. C., Savage, J. C., & van Goozen, S. (2013). Affective startle potentiation in juvenile offenders: The role of conduct problems and psychopathic traits. Social Neuroscience, 8, 112121.Google Scholar
Tarullo, A. R., & Gunnar, M. R. (2006). Child maltreatment and the developing HPA axis. Hormones and Behavior, 50, 632639.Google Scholar
Teicher, M. H., Andersen, S. L., Polcari, A., Anderson, C. M., & Navalta, C. P. (2002). Developmental neurobiology of childhood stress and trauma. Psychiatric Clinics of North America, 25, 397426.Google Scholar
Teicher, M. H., Samson, J. A., Sheu, Y., Polcari, A., & McGreenery, C. E. (2010). Hurtful words: Association of exposure to peer verbal abuse with elevated psychiatric symptom scores and corpus callosum abnormalities. American Journal of Psychiatry, 167, 14641471.Google Scholar
Thompson, R. A., Lewis, M. D., & Calkins, S. D. (2008). Reassessing emotion regulation. Child Development Perspectives, 2, 124131.Google Scholar
Tomoda, A., Navalta, C. P., Polcari, A., Sadato, N., & Teicher, M. H. (2009). Childhood sexual abuse is associated with reduced gray matter volume in visual cortex of young women. Biological Psychiatry, 66, 642648.Google Scholar
Toufexis, D. J., Myers, K. M., & Davis, M. (2006). The effect of gonadal hormones and gender on anxiety and emotional learning. Hormones and Behavior, 50, 539549.Google Scholar
Trickett, P. K., Noll, J. G., Susman, E. J., Shenk, C. E., & Putnam, F. W. (2010). Attenuation of cortisol across development for victims of sexual abuse. Development and Psychopathology, 22, 165175.Google Scholar
Vaidyanathan, U., Hall, J. R., Patrick, C. J., & Bernat, E. M. (2011). Clarifying the role of defensive reactivity deficits in psychopathy and antisocial personality using startle reflex methodology. Journal of Abnormal Psychology, 120, 253.Google Scholar
van Goozen, S. H., Fairchild, G., Snoek, H., & Harold, G. T. (2007). The evidence for a neurobiological model of childhood antisocial behavior. Psychological Bulletin, 133, 149182.Google Scholar
van Goozen, S. H., Snoek, H., Matthys, W., van Rossum, I., & van Engeland, H. (2004). Evidence of fearlessness in behaviourally disordered children: A study on startle reflex modulation. Journal of Child Psychology and Psychiatry, 45, 884892.Google Scholar
Viding, E., Blair, R. J. R., Moffitt, T. E., & Plomin, R. (2005). Evidence for substantial genetic risk for psychopathy in 7-year-olds. Journal of Child Psychology and Psychiatry, 46, 592597.Google Scholar
Viding, E., Fontaine, N. M., & McCrory, E. J. (2012). Antisocial behaviour in children with and without callous-unemotional traits. Journal of the Royal Society of Medicine, 105, 195200.Google Scholar
Viding, E., Jones, A. P., Paul, J. F., Moffitt, T. E., & Plomin, R. (2008). Heritability of antisocial behaviour at 9: Do callous-unemotional traits matter? Developmental Science, 11, 1722.Google Scholar
Vrana, S. R., Spence, E. L., & Lang, P. J. (1988). The startle probe response: A new measure of emotion? Journal of Abnormal Psychology, 97, 487.Google Scholar
Walker, D. L., Toufexis, D. J., & Davis, M. (2003). Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress and anxiety. European Journal of Pharmacology, 463, 199216.Google Scholar
Waters, A. M., Lipp, O. V., & Spence, S. H. (2005). The effects of affective picture stimuli on blink modulation in adults and children. Biological Psychiatry, 68, 257281.Google Scholar
Waters, A. M., Neumann, D. L., Henry, J., Caske, M. G., & Ornitz, E. M. (2008). Baseline and affective startle modulation by angry and neutral faces in 4- to 8-year-old anxious and non-anxious children. Biological Psychiatry, 78, 1019.Google Scholar
Webster-Stratton, C., & Reid, M. (2003). The incredible years parents, teachers, and children training series: A multifaceted treatment approach for young children with conduct problems. In Kazdin, A. E. & Weisz, J. R. (Eds.), Evidence-based psychotherapies for children and adolescents (pp. 224240). New York: Guilford Press.Google Scholar
Weems, C. F., & Carrion, V. G. (2007). The association between PTSD symptoms and salivary cortisol in youth: The role of time since the trauma. Journal of Traumatic Stress, 20, 903907.Google Scholar
White, S. F., & Frick, P. J. (2010). Callous-unemotional traits and their importance to causal models of severe antisocial behavior in youth. In Salekin, R. & Lynam, D. (Eds.), Handbook of child and adolescent psychopathy (pp. 135155). New York: Guilford Press.Google Scholar