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The Role of Cardiovascular Risk Factors in Alzheimer's Disease

Published online by Cambridge University Press:  07 November 2014

Ramit Ravona-Springer ,
Michael Davidson  and
Shlomo Noy
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Abstract

The distinction between Alzheimer's disease and vascular dementia, the two most common types of dementia, has been undermined by recent advances in epidemiologic, clinical, imaging, and neuropathological studies. Cardiovascular risk factors, traditionally regarded as distinguishing criteria between the two entities, have been shown to be associated with both AD and vascular dementia. In this article, we propose mechanisms of action of cardiovascular risk factors in AD, suggest possible explanations for the overlap with vascular dementia and discuss the implications this might have on future differential diagnosis, research, and treatment strategies.

Type
Review
Information
CNS Spectrums , Volume 8 , Issue 11: Alzheimer's Disease in the 21st Century , November 2003 , pp. 824 - 831
Copyright
Copyright © Cambridge University Press 2003

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