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Psychopharmacology of Depression in the Next Millennium

Published online by Cambridge University Press:  07 November 2014

Paul J. Goodnick
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Abstract

Over the last half of the 20th century, there have been a series of psychopharmacologic strategies for treatment of depression. As we approach the next century, new therapies in varying stages of American release are being developed. This review will focus on information available for the following proposed antidepressants: 1) reboxetine, a norepinephrine selective reuptake inhibitor; 2) milnacipran, a combined serotonin/norepinephrine reuptake inhibitor; 3) a new enantiomer of fluoxetine, a selective serotonin reuptake inhibitor; 4) duloxetine, another combined serotonin/norepinephrine reuptake inhibitor; 5) sunepitron, a combined 5-HT1A agonist and α2 antagonist; and, 6) MK-869, a substance P inhibitor. Finally, other possible developing directions will be reviewed, including corticotropin-releasing factor.

Type
Feature Articles
Information
CNS Spectrums , Volume 4 , Issue 7: Depression at the Millennium: Time for a Biological Understanding , July 1999 , pp. 21 - 35
Copyright
Copyright © Cambridge University Press 1999

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References

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