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Psychiatric Symptoms Associated with Brain Tumors: A Clinical Enigma

Published online by Cambridge University Press:  07 November 2014

Despina Moise  and
Subramoniam Madhusoodanan
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Abstract

Patients in psychiatric settings may present with medical conditions, such as brain tumors, which may or may not be associated with neurological symptoms. In some cases, patients may only have psychiatric symptoms, such as mood changes (depression or mania), psychotic symptoms, panic attacks, changes in personality, or memory difficulties. Brain tumors may be detected in patients at their first presentation to mental health services or sometimes in patients with well-established psychiatric diagnoses.This article presents the case of a 29-year-old woman who was treated for >4 years for posttraumatic stress disorder and borderline personality traits, who developed depressive symptoms and memory difficulties. However, she did not develop any major neurological signs or symptoms. Brain imaging showed the presence of a left thalamic tumor, later confirmed as glioblastoma multiforme. She underwent surgical treatment and radiation therapy. With this we show that in some cases, brain tumors can be neurologically silent and only present atypical psychiatric symptoms.

Type
Case Report
Information
CNS Spectrums , Volume 11 , Issue 1 , January 2006 , pp. 28 - 31
Copyright
Copyright © Cambridge University Press 2006

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References

REFERENCES

1.Madhusoodanan, S, Danan, D, Brenner, R, Bogunovic, O. Brain tumor and psychiatric manifestations: a case report and brief review. Ann Clin Psychiatry. 2004;16;111–113.Google Scholar
2.Uribe, VM. Psychiatric symptoms and brain tumor. Am Fam Physician. 1986;34:95–98.Google Scholar
3.Filley, CM, Kleinschmidt-DeMasters, BK. Neurobehavioral presentations of brain neoplasms. West J Med. 1995;163:19–25.Google Scholar
4.Binder, RL. Neurologically silent brain tumors in psychiatric hospital admissions: three cases and a review. J Clin Psychiatry. 1983;44:94–97.Google Scholar
5.Jarquin-Valdivia, AA. Psychiatric symptoms and brain tumors. Arch Neurol. 2004;61:1800–1804.Google Scholar
6.Lin, L, Liao, SC, Lee, YJ, Tseng, MC, Lee, MB. Brain tumor presenting as anorexia nervosa in a 19-year-old man. J Formos Med Assoc. 2003;102:737–740.Google ScholarPubMed
7.Krauthammer, C, Klerman, GL. Secondary mania: manic syndromes associated with antecedent physical illness or drugs. Arch Gen Psychiatry. 1978;35:1333–1339.Google Scholar
8.Jamieson, RC, Wells, CE. Manic psychosis in a patient with multiple metastatic brain tumors. J Clin Psychiatry. 1979;40:280–283.Google Scholar
9.Burns, JM, Swerdlow, RH. Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign. Arch Neurol. 2003;60:437–440.Google Scholar
10.Folstein, MF, Folstein, SE, McHugh, PR. “Mini-mental state.” A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189–198.Google Scholar
11.Teasdale, G, Jennet, B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974;2:81–84.Google Scholar