Paroxetine is used to treat patients with depression with anxiety disorders, and has a faster effect and better long-term efficacy than imipramine. Aiming at the strong psychological defense of college students majoring in painting, painting can reduce the psychological defense mechanism of painters and better observe subconscious thoughts. In order to determine the multidirectional treatment of learning anxiety disorders in painting college students, a combination of paroxetine drugs and painting therapy was conducted.

In this study, 60 college students majoring in painting, 30 patients treated with paroxetine drug and painting therapy, and 30 patients without combination therapy were studied, and the analysis data were processed using SPSS25.0 and the Learning Anxiety Scale to explore the effect of paroxetine drug and painting therapy on learning anxiety disorder among college students majoring in painting. At the same time, the experimental induction paradigm was adopted to stimulate learning anxiety events.

College students majoring in painting who received paroxetine medication and painting therapy on time showed a lower level of study anxiety than the standard level of 8.00, which was 6.97. No combination therapy resulted in a learning anxiety level of 8.59 when the learning anxiety event was triggered. The relationship between paroxetine drugs and painting therapy and study anxiety had a significant moderating effect, resulting in β=0.022, P<0.01.

Paroxetine medication and painting therapy can effectively relieve the study anxiety of college students majoring in painting.