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Overall Diagnostic Assessment of Mixed Episodes in Bipolar Disorder

Published online by Cambridge University Press:  07 November 2014

Extract

The diagnosis of bipolar disorder is made according to the fulfillment of symptom criteria as operationally defined by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. These criteria encompass both cross-sectional and historical data, along with pertinent corroborative features such as family history, chronobiological sensitivities, treatment outcomes, longitudinal course, and patterns of recurrence. In addition, one classifies a current illness state as involving pure mania, hypomania, a mixed episode, a depressed phase, or euthymia. Mixed states, as originally described by Kraepelin, were thought to represent transitional phenomena en route to the emergence of a frank manic or depressive episode. Today, however, mixed episodes are thought to comprise an important subgroup of syndromically ill individuals with bipolar disorder.

Type
Research Article
Copyright
Copyright © Cambridge University Press 2009

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References

1.Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC; American Psychiatric Association; 1994.Google Scholar
2.Spitzer, RL, Endicott, J, Robins, E. Research Diagnostic Criteria: rationale and reliability. Arch Gen Psychiatry. 1978;34:773782.CrossRefGoogle Scholar
3.Berk, M, Dodd, S, Malhi, G. “Bipolar missed states”: the diagnosis and clinical salience of bipolar mixed states. Aust NZ J Psychiatry. 2005;39:215221.Google ScholarPubMed
4.Goldberg, JF, Perlis, RH, Bowden, CL et al. , Manic symptoms during depressive episodes in 1,380 patients with bipolar disorder: findings from the STEP-BD. Am J Psychiatry. 2009;166:173181.CrossRefGoogle ScholarPubMed
5.Hirschfeld, RM, Williams, JB, Spitzer, RL et al. , Development and validation of of a screening instrument for bipolar spectrum disorder: the Mood Disorders Questionnaire. Am J Psychiatry. 2000;157:18731875.CrossRefGoogle Scholar
6.Gunderson, JG, Weinberg, I, Daversa, MT et al. , Descriptive and longitudinal observations on the relationship of borderline personality disorder and bipolar disorder. Am J Psychiatry. 2006;163:11731178.CrossRefGoogle ScholarPubMed
7.Goldberg, JF, Harrow, M, Whiteside, JE. Risk for bipolar illness in patients initially hospitalized for unipolar depression. Am J Psychiatry. 2001;158(8):12651270.CrossRefGoogle ScholarPubMed
8.Geller, B, Zimmerman, B, Williams, M, Bolhofner, K, Craney, JL. Bipolar disorder at prospective follow-up of adults who had prepubertal major depressive disorder. Am J Psychiatry. 2001;158(1):125127.CrossRefGoogle ScholarPubMed
9.Goldberg, JF, Garno, JL, Callahan, AM, Kearns, DL, Kerner, B, Ackerman, SH. Overdiagnosis of bipolar disorder among substance use disorder inpatients with mood instability. J Clin Psychiatry. 2008;69(11):17511757.CrossRefGoogle ScholarPubMed