Anxiety disorder is a common psychological problem among college students, which seriously affects their study and life quality. As a special cultural background, the influence of mathematics culture on the anxiety disorder of college students has not been fully studied.

The study tries to integrate mathematics culture based on educational psychology to explore its effect on the prevention and treatment of anxiety disorders in college students. The experiment included 50 college students with anxiety disorder, half of whom were the experimental group of college students receiving educational psychology and mathematical culture treatment, and the other half were the control group of college students receiving general educational psychology rehabilitation treatment. Both groups of students were treated together for one semester in the same environment. After the deadline, anxiety items in the Stanford Acute Stress Response Questionnaire (SASRQ) were measured, and the higher the score, the more severe the anxiety symptoms.

The experimental results showed that after some time, the anxiety patients in the experimental group decreased from 25 to 8, the anxiety symptoms were effectively controlled, and the comprehensive score was 8.5 points. In the control group, there were still 18 students with anxiety, only 7 patients were reduced, the treatment effect was not good, and the comprehensive score was 15.8 points.

The mathematical cultural education based on educational psychology proposed in this study has a positive effect on the anxiety disorder of college students. It timely adjusts the students’ attitude toward mathematics learning and reduces the degree of anxiety disorder of college students.