Due to economic pressure and environmental impact, college students often hesitate when planning their travels, resulting in anxiety to some extent. The conventional treatment method has relatively little effect on the treatment of college students’ travel anxiety disorder, so the study will use alprazolam combined with biofeedback therapy to intervene and treat college students’ travel anxiety disorder.

72 college students with travel anxiety disorder from a certain university were selected as the research subjects and divided into Group C and Group D according to the driver allocation method. Group C received traditional medication or psychological intervention, while Group D received a combination of alprazolam and biofeedback therapy. After the experiment, the data was processed using SPSS 20.0 statistical software.

The number of effective cases in Group D reached 30, with an effective rate of 95.38%, while Group C only had 81.54%, significantly lower than Group D; After treatment, the anxiety score of Group D was 29.1 ± 3.6, lower than Group C’s 39.0 ± 3.8, and significantly lower than the 41.7 ± 3.9 before the experiment; After treatment, the number of nausea and vomiting in Group D was 1, appetite loss was 3, and hair loss was 2 points, both lower than those in Group C. The incidence of adverse reactions after treatment was relatively low.

The combination of alprazolam and biofeedback therapy is effective in the intervention and treatment of travel anxiety disorder in college students.