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Group independent component analysis reveals alternation of right executive control network in Internet gaming disorder

Published online by Cambridge University Press:  29 August 2017

Lingxiao Wang ,
Yifen Zhang ,
Xiao Lin ,
Hongli Zhou ,
Xiaoxia Du  and
Guangheng Dong
Lingxiao Wang
Affiliation:
Department of Psychology, Zhejiang Normal University, Jinhua, P.R. China
Yifen Zhang
Affiliation:
Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, P.R. China
Xiao Lin
Affiliation:
Department of Psychology, Zhejiang Normal University, Jinhua, P.R. China Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, P.R. China
Hongli Zhou
Affiliation:
Department of Psychology, Zhejiang Normal University, Jinhua, P.R. China
Xiaoxia Du
Affiliation:
Department of Physics, Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, P.R. China
Guangheng Dong*
Affiliation:
Department of Psychology, Zhejiang Normal University, Jinhua, P.R. China Institute of Psychological and Brain Researches, Zhejiang Normal University, Jinhua, P.R. China
*
*Address for correspondence: Guangheng Dong, Department of Psychology, Zhejiang Normal University, 688 Yingbin Road, Jinhua, Zhejiang Province 321004, P.R. China. Email: [email protected]
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Abstract

Objective

Previous studies have demonstrated that individuals with Internet gaming disorder (IGD) showed attentional bias toward gaming-related cues and exhibited impaired executive functions. The purpose of this study was to explore the alternations in related functional brain networks underlying attentional bias in IGD subjects.

Methods

Eighteen IGD subjects and 19 healthy controls (HC) were scanned with functional magnetic resonance imaging while they were performing an addiction Stroop task. Networks of functional connectivity were identified using group independent component analysis (ICA).

Results

ICA identified 4 functional networks that showed differences between the 2 groups, which were related to the right executive control network and visual related networks in our study. Within the right executive control network, in contrast to controls, IGD subjects showed increased functional connectivity in the temporal gyrus and frontal gyrus, and reduced functional connectivity in the posterior cingulate cortex, temporal gyrus, and frontal gyrus.

Conclusion

These findings suggest that IGD is related to abnormal functional connectivity of the right executive control network, and may be described as addiction-related abnormally increased cognitive control processing and diminished response inhibition during an addiction Stroop task. The results suggest that IGD subjects show increased susceptibility towards gaming-related cues but weakened strength of inhibitory control.

Keywords

Addiction Stroop taskattentional biasexecutive control networkindependent component analysisInternet gaming disorder
Type
Original Research
Information
CNS Spectrums , Volume 23 , Special Issue 5: Theme: Obsessive-Compulsive Disorder , October 2018 , pp. 300 - 310
Copyright
© Cambridge University Press 2017 

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Footnotes

This research was approved by the Human Investigations Committee of Zhejiang Normal University. All participants provided written informed consent.

This research was supported by the National Science Foundation of China (31371023). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We received no assistance from technical writers, language editors or writing agencies in preparing this manuscript.

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