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Cerebral Ventricular Asymmetry and Ventriculomegaly Interact to Increase Risk for Schizophrenia: A Case Report and Recommendation for Routine Fetal Sonography

Published online by Cambridge University Press:  07 November 2014

Elionora Katz ,
Jessica A. Burket ,
Stephanie M. Rosse ,
Richard B. Rosse ,
Barbara L. Schwartz  and
Stephen I. Deutsch
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Abstract

A 60-year-old patient with a clinical diagnosis of schizophrenia underwent a magnetic resonance imaging (MRI) scan related to the evaluation of isolated seizures that emerged while medicated with clozapine. Unexpectedly, the MRI scan revealed evidence of asymmetric and enlarged cerebral ventricles that were interpreted as congenital in origin. The presence of both congenital lateral ventricular asymmetry and ventriculomegaly may interact to increase risk of schizophrenia. The history and clinical features, including cognitive testing, of the illustrative patient are presented.

Type
Review Article
Information
CNS Spectrums , Volume 15 , Issue 9 , September 2010 , pp. 574 - 578
Copyright
Copyright © Cambridge University Press 2010

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