Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-25T16:43:47.175Z Has data issue: false hasContentIssue false

Anticholinergic Load and Comorbid Conditions

Published online by Cambridge University Press:  07 November 2014

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
CME-Accredited Roundtable Monograph
Copyright
Copyright © Cambridge University Press 2004

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Blazer, DG, Federspiel, CF, Ray, WA, Schaffner, W. The risk of anticholinergic toxicity in the elderly: a study of prescribing practices in two populations. J Gerontol. 1983;38:3135.Google Scholar
2.Pollock, BG. Geriatric psychiatry: psychopharmacology: peneral principles. In: Sadock, BJ, Sadock, VA, eds. Kaplan & Sadock's Comprehensive Textbook of Psychiatry. Baltimore, MD: Williams & Wilkins; 2000:30863090.Google Scholar
3.Cohen, RM, Podruchny, TA, Bokde, AL, et al.Higher in vivo muscarinic-2 receptor distribution volumes in aging subjects with an apolipoprotein E-epsilon4 allele. Synapse. 2003;49(3):150156.Google Scholar
4.Feinberg, M. The problems of anticholinergic adverse effects in older patients. Drugs Aging. 1993;3:335348.CrossRefGoogle ScholarPubMed
5.Mulsant, BH, Pollock, BG, Kirshner, M, Shen, C, Dodge, H, Ganguli, M. Serum anticholinergic activity in a community-based sample of older adults: relationship with cognitive performance. Arch Gen Psychiatry. 2003;60(2):198203.Google Scholar
6.Tune, LE. Serum anticholinergic activity levels and delirium in the elderly. Sem Clin Neuropsychiatry. 2000;5:149153.Google ScholarPubMed
7.Rovner, BW, David, A, Lucas-Blaustein, MJ, Conklin, B, Filipp, L, Tune, L. Self-care capacity and anticholinergic drug levels in nursing home patients. Am J Psychiatry. 1988;145(1):107109.Google Scholar
8.Pardridge, WM. CNS drug design based on principles of blood-brain barrier transport. J Neurochem. 1998;70(5):17811792.Google Scholar
9.Pakulski, C, Drobnik, L, Millo, B. Age and sex as factors modifying the function of the blood-cerebrospinal fluid barrier. Med Sci Monit. 2000;6(2):314318.Google Scholar