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Optimizing Outcomes in Schizophrenia: Long-acting Depots and Long-term Treatment

Published online by Cambridge University Press:  10 December 2012

Debbi A. Morrissette  and
Stephen M. Stahl
Debbi A. Morrissette
Affiliation:
Neuroscience Education Institute, Carlsbad, CA, USA
Stephen M. Stahl*
Affiliation:
Neuroscience Education Institute, Carlsbad, CA, USA Department of Psychiatry, University of California-San Diego, San Diego, CA, USA
*
*Address correspondence to: Stephen M. Stahl, M.D., Ph.D. Neuroscience Education Institute, 1930 Palomar Point Way, Suite 101, Carlsbad, CA 92008. (Email [email protected])
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Abstract

Antipsychotics are the mainstay of treatment for patients with schizophrenia. However, these medications only work if they are taken and perhaps work best if they are taken for longer periods of time than seen in typical research trials. Here we explore the idea of “time as a drug” by reviewing the data showing the potential benefits of long-term antipsychotic use. We also discuss the utility of depot antipsychotic formulations for improving the chances of attaining long-term therapeutic results.

Type
CME Article
Information
CNS Spectrums , Volume 17 , Issue s1: CME SUPPLEMENT: Optimizing Care for Patients with Schizophrenia , November 2012 , pp. 10 - 21
Copyright
Copyright © Cambridge University Press 2012

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