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Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients

Published online by Cambridge University Press:  25 November 2014

Stephen M. Stahl
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Abstract

ISSUE:Many individuals with total blindness can develop a circadian rhythm disorder—called non-24 sleep wake syndrome—because they cannot detect light to resynchronize their sleep–wake cycles. A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in these patients, resetting their circadian sleep–wake clocks.

Type
Brainstorms
Information
CNS Spectrums , Volume 19 , Issue 6 , December 2014 , pp. 475 - 478
Copyright
Copyright © Cambridge University Press 2014 

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