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An Evaluation of the Supplementation of Dietary-Modified Palygorskite on Growth Performance, Zearalenone Residue, Serum Metabolites, and Antioxidant Capacities in Broilers Fed a Zearalenone-Contaminated Diet

Published online by Cambridge University Press:  01 January 2024

Qiao Xu ,
Yueping Chen ,
Yefei Cheng ,
Yue Su ,
Chao Wen ,
Wenbo Wang ,
Aiqin Wang  and
Yanmin Zhou
Qiao Xu
Affiliation:
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China
Yueping Chen
Affiliation:
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China
Yefei Cheng
Affiliation:
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China
Yue Su
Affiliation:
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China
Chao Wen
Affiliation:
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China
Wenbo Wang
Affiliation:
Center of Eco-material and Green Chemistry, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P.R. China R&D Center of Xuyi Palygorskite Applied Technology, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Xuyi 211700, P.R. China
Aiqin Wang
Affiliation:
Center of Eco-material and Green Chemistry, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P.R. China R&D Center of Xuyi Palygorskite Applied Technology, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Xuyi 211700, P.R. China
Yanmin Zhou*
Affiliation:
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, P.R. China
*
*E-mail address of corresponding author: [email protected]
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Abstract

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Zearalenone (ZEA), a common contaminant in food and feedstuffs, threatens human and animal health. The present study aimed to investigate the protective effects of modified palygorskite (MPal), a ZEA-targeted adsorbent, on broilers (young chickens) fed a ZEA-contaminated diet. Broilers were subjected to one of three treatments for a period of 42 days: a basal diet (control group), a ZEA- contaminated diet, and a ZEA-contaminated diet supplemented with 1 g/kg of MPal. Blood was collected for serum metabolite assay, and liver and kidney were sampled to determine ZEA residue and antioxidant-related parameters, using commercial spectrophotometric kits. Compared with the basal diet, the ZEA- contaminated diet resulted in compromised growth performance (reduced daily gain and feed intake during finisher period), disordered relative liver weight (decreased at 21 days but increased at 42 days), increased ZEA residue in liver and kidney, abnormal serum metabolites (decreased total protein content but increased alanine aminotransferase activity at 21 and 42 days, reduced albumin content at 21 days, and elevated aspartate aminotransferase activity at 42 days), and disrupted antioxidant capacities of broilers (increased total superoxide dismutase (T-SOD) activity in liver at 21 and 42 days, decreased T-SOD activity in kidney at 21 and 42 days, and in serum at 42 days, greater malondialdehyde accumulation in liver and kidney at 42 days, and lower glutathione content in kidney at 21 days). The adverse consequences resulting from the ZEA-contaminated diet were relieved by the supplementation of MPal (except albumin concentration in serum and T-SOD activity in liver at 21 days), with the values of growth-performance parameters, liver weight, renal ZEA accumulation, total protein content, transaminase activity at 42 days, and antioxidant indexes being similar to those in the control group. These results suggested that MPal supplementation could promote growth performance, attenuate liver damage, and improve the antioxidant abilities of broilers fed ZEA-contaminated diet by reducing ZEA accumulation.

Keywords

BroilersKidneyLiverModified PalygorskiteZearalenone
Type
Article
Information
Clays and Clay Minerals , Volume 66 , Issue 6 , December 2018 , pp. 474 - 484
Copyright
Copyright © Clay Minerals Society 2018

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