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A vulnerable interval for cerebral injury—comparison of hypothermic circulatory arrest and low flow cardiopulmonary bypass

Published online by Cambridge University Press:  19 August 2008

Craig K. Mezrow ,
Peter S. Midulla ,
Ali M. Sadeghi ,
Otto Dapunt ,
Alejandro Gandsas ,
Howard Shiang ,
David A. D'Alessandro  and
Randall B. Griepp
Craig K. Mezrow*
Affiliation:
From the Mount Sinai Medical Center, New York
Peter S. Midulla
Affiliation:
From the Mount Sinai Medical Center, New York
Ali M. Sadeghi
Affiliation:
From the Mount Sinai Medical Center, New York
Otto Dapunt
Affiliation:
From the Mount Sinai Medical Center, New York
Alejandro Gandsas
Affiliation:
From the Mount Sinai Medical Center, New York
Howard Shiang
Affiliation:
From the Mount Sinai Medical Center, New York
David A. D'Alessandro
Affiliation:
From the Mount Sinai Medical Center, New York
Randall B. Griepp
Affiliation:
From the Mount Sinai Medical Center, New York
*
Mr. Craig Mezrow, Department of Cardiothoracic Surgery, Mount Sinai Medical Center, P.O. Box 1028, One Gustave L. Levy Place, New York, NY 10029, USA. Tel. (212) 241-4125; Fax. (212) 534-3357.
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Extract

Over the past two decades, advances in equipment used for cardiopulmonary bypass and in operative techniques have resulted in a tremendous decrease in the mortality of patients undergoing surgical repair of congenital heart disease utilizing hypothermic circulatory arrest. Despite the widespread use of hypothermic arrest, opinion is not unanimous with regard to its safety. Previous studies which have examined neurological outcome following repair of congenital heart disease in infancy have generally agreed that when the period of arrest exceeds 60 minutes, there is increasing risk of cerebral injury.

Keywords

Cerebral metabolismhypothermic circulatory arrestlow flow bypass
Type
World Forum for Pediatric Cardiology Symposium on Cardiopulmonary Bypass (Part 1)
Information
Cardiology in the Young , Volume 3 , Issue 3 , July 1993 , pp. 287 - 298
Copyright
Copyright © Cambridge University Press 1993

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References

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