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Treatment of haemoptysis in pulmonary atresia with tranexamic acid

Published online by Cambridge University Press:  20 July 2012

Matthew J. Devine  and
Dorothy J. Radford
Matthew J. Devine
Affiliation:
Adult Congenital Heart Disease Unit, The Prince Charles Hospital, Chermside, Brisbane, Australia
Dorothy J. Radford*
Affiliation:
Adult Congenital Heart Disease Unit, The Prince Charles Hospital, Chermside, Brisbane, Australia
*
Correspondence to: Dr D. Radford, Consultant, Adult Congenital Heart Disease Unit, The Prince Charles Hospital, Rode Road, Chermside 4032, Brisbane, Australia. Tel: 61 7 3139 4000; Fax: 61 7 3139 4715; E-mail: [email protected]
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Abstract

We report the case of a young woman with continuing haemoptysis, pulmonary atresia, previous shunt surgery, and pulmonary hypertension. She was not suitable for further surgery or for therapeutic embolisation of bronchial vessels. Treatment with tranexamic acid resolved the haemoptysis.

Keywords

Haemoptysiscongenital heart diseasetranexamic acid
Type
Brief Report
Information
Cardiology in the Young , Volume 23 , Issue 2 , April 2013 , pp. 304 - 305
Copyright
Copyright © Cambridge University Press 2012 

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References

1. Haroutunian, L, Neil, CA. Pulmonary complications of congenital heart disease: hemoptysis. Am Heart J 1972; 84: 540–559.CrossRefGoogle ScholarPubMed
2. Diller, GP, Gatzoulis, MA. Pulmonary vascular disease in adults with congenital heart disease. Circulation 2007; 115: 1039–1050.CrossRefGoogle ScholarPubMed
3. Daliento, L, Somerville, J, Presbitero, P, et al. Eisenmenger syndrome. Factors relating to deterioration and death. Eur Heart J 1998; 19: 1845–1855.CrossRefGoogle ScholarPubMed
4. Coss-Bu, JA, Sachdeva, RC, Bricker, JT, et al. Hemoptysis: a 10-year retrospective study. Pediatrics 1997; 100: e7.CrossRefGoogle ScholarPubMed
5. Novikova, N, Hofmeyr, GJ. Tranexamic acid for preventing postpartum haemorrhage. Cochrane Database Syst Rev 2010; 7: CD007872.Google Scholar
6. Graff, GR. Treatment of recurrent severe hemoptysis in cystic fibrosis with tranexamic acid. Respiration 2001; 68: 91–94.CrossRefGoogle ScholarPubMed
7. Henry, DA, Carless, PA, Moxey, AJ, et al. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2007: CD001886.Google ScholarPubMed
8. CRASH-2 Trial Collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376: 23–32.CrossRefGoogle Scholar
9. Brinson, GM, Noone, PG, Mauro, MA, et al. Bronchial artery embolization for the treatment of hemoptysis in patients with cystic fibrosis. Am J Respir Crit Care Med 1998; 157: 1951–1958.CrossRefGoogle ScholarPubMed
10. Hartnell, GG. Embolization in the treatment of acquired and congenital abnormalities of the heart and thorax. RadioGraphics 1993; 13: 1349–1362.CrossRefGoogle ScholarPubMed