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Transplacental treatment of foetal supraventricular tachycardia with triple antiarrhythmic combination to avoid intra-foetal intervention

Published online by Cambridge University Press:  13 January 2022

Kadir Babaoglu Open the ORCID record for Kadir Babaoglu [Opens in a new window] ,
Yasemin Dogan  and
Orhan Uzun Open the ORCID record for Orhan Uzun [Opens in a new window]
Kadir Babaoglu*
Affiliation:
Kocaeli University School of Medicine, Department of Pediatric Cardiology, Kocaeli, Turkey
Yasemin Dogan
Affiliation:
Kocaeli University School of Medicine, Department of Perinatology, Kocaeli, Turkey
Orhan Uzun
Affiliation:
University Hospital of Wales, Department of Pediatric Cardiology, Wales, UK
*
Author for correspondence: Prof. Dr. Kadir Babaoglu, Kocaeli University School of Medicine, Department of Pediatric Cardiology, Kocaeli, Turkey. Tel: +902623038035; Fax: 902623038003. E-mail: [email protected]
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Abstract

Although a high percentage of foetuses with supraventricular tachycardia respond to single or dual antiarrhythmic therapy, on occasion when there is no response to these combination regimens, direct intra-foetal therapy remains the only choice, albeit such an approach carries a potential risk to the foetus.

Data with regard to the safety and efficacy of triple antiarrhythmic combination have not been reported before. Here, we present a foetus with intractable tachycardia in whom arrhythmia termination was successfully achieved with triple oral antiarrhythmic therapy.

Keywords

Supraventricular tachycardiafoetaltriple combinationtherapy
Type
Brief Report
Information
Cardiology in the Young , Volume 32 , Issue 7 , July 2022 , pp. 1162 - 1165
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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References

Simpson, JM, Sharland, GK. Fetal tachycardias: management and outcome of 127 consecutive cases. Heart 1998; 79: 576–581.10.1136/hrt.79.6.576CrossRefGoogle ScholarPubMed
Frohn-Mulder, IM, Stewart, PA, Witsenburg, M, Den Hollander, NS, Wladimiroff, JW, Hess, J. The efficacy of flecainide versus digoxin in the management of fetal supraventricular tachycardia. Prenat Diagn 1995; 15: 1297–1302.10.1002/pd.1970151309CrossRefGoogle ScholarPubMed
Ebenroth, ES, Cordes, TM, Darragh, RK. Second-line treatment of fetal supraventricular tachycardia using flecainide acetate. Pediatr Cardiol 2001; 22: 483–487.10.1007/s002460010279CrossRefGoogle ScholarPubMed
Lulić Jurjević, R, Podnar, Tž, Vesel, S. Diagnosis, clinical features, management, and post-natal follow-up of fetal tachycardias. Cardiol Young 2009; 19: 486–493.10.1017/S1047951109990497CrossRefGoogle ScholarPubMed
Jaeggi, ET, Carvalho, JS, De Groot, E, et al. Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized multicenter study. Circulation 2011; 124: 1747–1754.10.1161/CIRCULATIONAHA.111.026120CrossRefGoogle ScholarPubMed
Hahurij, ND, Blom, NA, Lopriore, E, et al. Perinatal management and long-term cardiac outcome in fetal arrhythmia. Early Hum Dev 2011; 87: 83–87.10.1016/j.earlhumdev.2010.11.001CrossRefGoogle ScholarPubMed
Uzun, O, Babaoglu, K, Sinha, A, Massias, S, Beattie, B. Rapid control of fetal supraventricular tachycardia with digoxin and flecainide combination treatment. Cardiol Young 2012; 22: 372–380.10.1017/S1047951111001272CrossRefGoogle ScholarPubMed
Shah, A, Moon-Grady, A, Bhogal, N, et al. Effectiveness of sotalol as first-line therapy for fetal supraventricular tachyarrhythmias. Am J Cardiol 2012; 109: 1614–1618.10.1016/j.amjcard.2012.01.388CrossRefGoogle ScholarPubMed
Oudijk, MA, Michon, MM, Kleinman, CS, et al. Sotalol in the treatment of fetal dysrhythmias. Circulation 2000; 101: 2721–2726.CrossRefGoogle ScholarPubMed