Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-05T12:09:01.694Z Has data issue: false hasContentIssue false

Tomas Pexieder (1941-1995): Scientist, Artist and Innovator

Published online by Cambridge University Press:  19 August 2008

Edward B. Clark
Affiliation:
Medical Director's OfficePrimary Children's Medical Center100 North Medical DriveSalt Lake City, Utah 84113, USA Tel, 801-588-2360; Fax. 801-588-2380 e-mail: [email protected]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Special Tribute
Copyright
Copyright © Cambridge University Press 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Pexieder, T. Cell death in the morphogenesis and teratogenesis of the heart. Adv Anat Embryol Cell Biol 1975; 51: Fasc 3; 1100.Google ScholarPubMed
2.Pexieder, T (ed), Mechanisms of Cardiac Morphogenesis and Teratogenesis. Perspectives in Cardiovascular Research. Raven Press, New York, 1981.Google Scholar
3.Aranega, A and Pexieder, T (eds). Correlations Between Experimental Cardiac Embryology and Teratology and Congenital Cardiac Defects. University of Granada Press, Granada, 1989.Google Scholar
4.Pexieder, T. Development of the outflow tract of the embryonic heart. In: Rosenquist, GC, Bergsma, D (eds). Morphogenesis and Malformation of the Cardiovascular System. Birth Defects: Orig Art Ser Vol XIV, No 7. AR Liss Inc., New York, 1978, pp 2968.Google ScholarPubMed
5.Pexieder, T. Heart anomalies in fetal mouse trisomy. In: Rosenquist, GC, Bergsma, D (eds). Morphogenesis and Malformation of the Cardiovascular System. Birth Defects: Orig Art Ser Vol XIV, No 7. AR Liss Inc, New York, 1978, pp 387390.Google ScholarPubMed
6.Pexieder, T. Discussion of the topic: effects of modifying the embryonic circulation. In: Rosenquist, GC, Bergsma, D (eds). Morphogenesis and Malformation of the Cardiovascular System. Birth Defects: Orig Art Ser Vol XIV, No 7, AR Liss Inc, New York, 1978, pp 449455.Google Scholar
7.Pexieder, T. Mechanisms of teratogenesis in hemodynamically induced ventricular septal defect (VSD). In: Van Julsingha, EB, Tesh, JM, Fara, GM (eds). Advances in the Detection of Congenital Malformation. Europ Teratol Society, Hudsins Hill, 1979, pp 264268.Google Scholar
8.Pexieder, T. Cellular mechanisms underlying the normal and abnormal development of the heart. In: Van Praagh, R, Takao, A (eds). Etiology and Morphogenesis of Congenital Heart Disease. Futura Publishing Co., New York, 1980, pp 127153.Google Scholar
9.Pexieder, T, Christen, Y. Quantitative analysis of the shape development in the chick embryo heart. In: Pexieder, T (ed). Mechanisms of Cardiac Morphogenesis and Teratogenesis. Raven Press, New York, 1981, pp 4967.Google Scholar
10.Paschoud, N, Pexieder, T. Patterns of proliferation during the organogenetic phase of heart development in the chick. In: Pexieder, T (ed). Mechanisms of Cardiac Morphogenesis and Teratogenesis. Raven Press, New York, 1981, pp 7988.Google Scholar
11.Pexieder, T. Introduction (cell death). In: Pexieder, T (ed). Mechanisms of Cardiac Morphogenesis and Teratogenesis. Raven Press, New York, 1981, pp 9399.Google Scholar
12.Satow, Y, Hidaka, N, Miyabara, S, Pexieder, T. Comparative and morphometric study on the genetically programmed cell death in rat and chick embryonic heart. In: Pexieder, T (ed). Mechanisms of Cardiac Morphogenesis and Teratogenesis. Raven Press, New York, 1981, pp 115126.Google Scholar
13.Pexieder, T (ed). Mechanisms of Cardiac Morphogenesis and Teratogenesis. Raven Press, New York, 1981, pp 115126.Google Scholar
14.Pexieder, T, Miyabara, S, Gropp, A. Congenital heart disease in experimental mouse trisomies: incidence. In: Pexieder, T (ed). Mechanisms of Cardiac Morphogenesis and Teratogenesis. Raven Press, New York, 1981, pp 389398.Google Scholar
15.Pexieder, T. Cellular abnormalities leading to congenital heart disease. In: Godman, M (ed). Paediatric Cardiology, Vol. 4. Churchill Livingstone, Edinburgh, 1981, pp 2432.Google Scholar
16.Micheli, JL, Genton, N, Pexieder, T. Surgical problems in Siamese twins. In: Bettex, M, Genton, N, Stockman, M (eds). Kinderchirurgie, 2. Aufl G Thieme, Stuttgart, 1982, pp 12.212.7. [German]Google Scholar
17.Pexieder, T, Janecek, P. Organogenesis of the human embryonic and early fetal heart as studied by microdissection and SEM. In: Nora, JJ, Takao, A (eds). Congenital Heart Disease: Causes and Processes. Futura Press, Mount Kisco, 1984, pp 401421.Google Scholar
18.Pexieder, T, Patterson, DF. Early pathogenesis of conotruncal malformations in the Keeshond dog. In: Nora, JJ, Takao, A (eds). Congenital Heart Disease: Causes and Processes. Futura Press, Mount Kisco, 1984, pp 439457.Google Scholar
19.Pexieder, T, Christen, Y, Vuillemin, M, Patterson, DF. Comparative morphometric analysis of cardiac organogenesis in chick, mouse and dog embryos. In: Nora, JJ, Takao, A (eds). Congenital Heart Disease: Causes and Processes. Futura Press, Mount Kisco, 1984, pp 423438.Google Scholar
20.Pexieder, T, Baumann, H, Mieth, GD, Huch, A, Duc, G. Prospective recording of events during pregnancy and early childhood using a pregnancy pass. Results of a pilot study in Zurich. In: de Wals, Ph, Weatherall, JAC, Lechat, MF (eds). Registration of Congenital Anomalies in Eurocat Centres 1979–1983. Cabay, Louvain-La-Neuve, 1985, pp 214224.Google Scholar
21.Pexieder, T. Teratogens. In: Pierpont, MEM, Moller, JH (eds). The Genetics of Cardiovascular Disease. Martinus Nijhoff, Boston, 1986, pp 2568.Google Scholar
22.Pexieder, T, de Wals, Ph, Bosi, G, Stoll, C, Gallez, A, Houston, A, Vliers, A, Wilkinson, J. Preliminary results of the subproject for the registration and follow-up of congenital heart disease. In: De Wals, Ph, Lechat, MF (eds). Eurocat Report 2, Brussels, 1987, pp 211227.Google Scholar
23.Pexieder, T. Techniques of in vitro fertilization. In: Revaz, C (ed). Fecondation in vitro et Transfert d'Embryon. Medecine et Hygiene, Geneve, 1987, pp 5981. [French]Google Scholar
24.Bersinger, N, Pexieder, T, Boillat, E, Janecek, P. Determination of serum pregnancy-associated endometrial alpha-2-globulin before and after embryo transfer in a clinical IVF-ET programme. In: Tomoda, Y, Mizutani, S, Narita, O, Klopper, A (eds). Placental and Endometrial Proteins: Basic and Clinical Aspects. VSP, Utrecht, 1988, pp 381384.Google Scholar
25.Pexieder, T, Spertini, O, Bersinger, N, Boillat, E, Janecek, P. Combined use of alpha-2-PEG and EPPAF for assessment of implantation failure in IVFET. In: Genarrani, AR, Petraglia, F, Volpe, A, Facchinetti, F (eds). Recent Research on Gynecological Endocrinology. Parthenon Publishing Ltd., Canforth, 1988, pp 588591.Google Scholar
26.Pexieder, T, Vuillemin, M, Alaili, R, Veuthey, S, Patterson, DF, Scott, WJ. Experimental studies in the pathogenesis of conotruncal defects. In: Aranega, A, Pexieder, T (eds). Correlations berween Experimental Cardiac Embryology and Teratology and Congenital Cardiac Defects. University of Granada Press, Granada, 1989, pp 3792.Google Scholar
27.Vuillemin, M, Pexieder, T, Gropp, A, Winking, H. Pathogenesis of pulmonary artery stenosis and atresia in fetal mouse trisomy 13. In: Clark, EB, Takao, A (eds). Developmental Cardiology: Morphogenesis and Function. Futura Publish ing Co., Mount Kisco, 1990, pp 383407.Google Scholar
28.Veuthey, S, Pexieder, T, Scott, WJ. Pathogenesis of cardiac anomalies induced by trimethadione in the rat. In: Clark, EB, Takao, A (eds). Developmental Cardiology: Morphogenesis and Function. Futura Publishing Co., Mount Kisco, 1990, pp 453465.Google Scholar
29.Pexieder, T, Pfizenmaier Rousseil, M and Prados-Frutos, JC. Prenatal pathogenesis of the transposition of great arteries. In: Vogel, M, Buhlmeyer, K (eds). Transposition of the Great Arteries—25 Years After Rashkind Balloon Septostomy. Steinkopf Verlag, Darmstadt, 1992, pp 1127.CrossRefGoogle Scholar
30.Pexieder, T. Proper laboratory practice in experimental studies of abnormal cardiovascular development. In: Clark, EB, Markwald, RR, Takao, A (eds): Developmental Mechanisms of Heart Disease. Futura Publishing Co., Armonk, NY, 1995, pp 169174.Google Scholar
31.Pexieder, T, Jedlicka, S, Sugimara, K, Tatimatsu, A, Sato, H. Immunohistochemical localization of platelet-derived growth factor (PDGF) during cardiac morphogenesis in chick and mouse embryos and fetuses. In: Clark, EB, Markwald, RR, Takao, A (eds): Developmental Mechanisms of Heart Disease. Futura Publishing Co., Armonk, NY, 1995, pp 207212.Google Scholar
32.Pexieder, T. Conotruncus and its septation at the advent of the molecular biology era. In: Clark, EB, Markwald, RR, Takao, A (eds): Developmental Mechanisms of Heart Disease. Futura Publishing Co., Armonk, NY, 1995, pp 227247.Google Scholar
33.Pexieder, T, Blanc, O, Pelouch, V, Ostadalova, I, Milerova, M, Ostadal, B. Late fetal development of retinoic acid-induced transposition of great arteries: morphology, physiology and biochemistry. In: Clark, EB, Markwald, RR, Takao, A (eds): Developmental Mechanisms of Heart Disease. Futura Publishing Co., Armonk, NY, 1995, pp 297307.Google Scholar
34.Pexieder, T, Bloch, D. EUROCAT subproject on epidemiology of congenital heart disease: First analysis of the completed study. In: Clark, EB, Markwald, RR, Takao, A (eds): Developmental Mechanisms of Heart Disease. Futura Publishing Co., Armonk, NY, 1995, pp. 655671.Google Scholar
35.Pexieder, T. Age changes in the vascularization of the adipose tissue in rats. Exp Geront 1965; 1: 95103.CrossRefGoogle Scholar
36.Pexieder, T. A simple electric apparatus for automatic injection of vessels by pulsating pressure. Folia Morphol (Praha) 1965; 13: 423426.Google ScholarPubMed
37.Jelinek, R, Pexieder, T. The pressure of encephalic fluid in chick embryos between the 2nd and 6th day of incubation. Physiol Bophemoslov 1968; 17: 297305.Google ScholarPubMed
38.Pexieder, T. Some quantitative aspects on the development of aortic arches in chick embryos between the 2nd and 8th day of incubation. Folia Morphol (Praha) 1969; 17: 102136.Google ScholarPubMed
39.Pexieder, T. Blood pressure in the third and fourth aortic arch and morphogenetic influence of laminar blood streams-on the development of the vascular system of the chick embryo. Folia Morphol (Praha) 1969; 17: 273290.Google ScholarPubMed
40.Pexieder, T. Embryonic blood flow patterns and heart development. J Florida Med Assoc 1970; 57: 46.Google ScholarPubMed
41.Clark, EB, Markwald, RR, Takao, A (eds): Developmental Mechanisms of Heart Disease. Futura Publishing Co., Armonk, NY, 1995, pp. 655671.Google Scholar
42.Pexieder, T, Jelinek, R. Pressure of the CSF and the morphogenesis of the CNS. II Pressure necessary for normal development of brain vesicles. Folia Morphol (Praha) 1970; 18: 181192.Google ScholarPubMed
43.Pexieder, T. The tissue dynamics of heart morphogenesis. I. Cell death phenomena. A. Identification and morphology. Z Anat Entwickl Gesch 1972; 137: 270284.CrossRefGoogle ScholarPubMed
44.Pexieder, T. The tissue dynamics of heart morphogenesis. I. Cell death phenomena. B. Topography. Z Anat Entwickl Gesch 1972; 138: 241253.CrossRefGoogle ScholarPubMed
45.Krstic, R, Pexieder, T. Ultrastructure of cell death in bulbar cushions of chick embryo heart. Z Anat Entwickl Gesch 1973; 140: 337350.CrossRefGoogle ScholarPubMed
46.Pexieder, T. The tissue dynamics of heart morphogenesis. I Quantitative investigations. A. Method and values from areas without cell death foci. Ann Embryol Morph 1973; 6: 325334.Google Scholar
47.Pexieder, T. The tissue dynamics of heart morphogenesis. I. Quantitative investigations. B. Cell death foci. Ann Embryol Morph 1973; 6: 335346.Google Scholar
48.Pexieder, T. Teratogenic mechanisms in congenital cardiac anomalies. Acta Anat Neerl Scand 1975; 13: 311313.Google ScholarPubMed
49.Pexieder, T. The effects of hemodynamics on the morphology of the embryonic endocardium. Bull Assoc Anat 1976; 60: 399406. [French]Google Scholar
50.Pexieder, T. Changing scene in cardiac embryology. Herz 1979; 4: 7377.Google ScholarPubMed
51.Pexieder, T. Prenatal development of the endocardium. A review. Scan Electron Microsc 1981; II: 223253.Google Scholar
52.Becker, AE, Pexieder, T. European Society of Cardiology Working Group on Embryology and Teratology. Eur Heart J 1984; 5: 180182.CrossRefGoogle Scholar
53.Pexieder, T, Boillat, E, Janecek, P. Antisperm antibodies and in vitro fertilization failure. J IVFET 1985; 2: 229232.Google ScholarPubMed
54.Pexieder, T. Prenatal development of the endocardium; a review. Scanning Electron Microscopy 1986; V: 191220.Google Scholar
55.Vuillemin, M, Pexieder, T, Janecek, P, Stamm, H. Rabbit oviduct mucosa healing after accidental transmucosal suture passage. Microsurgery 1986; 7: 138145.CrossRefGoogle ScholarPubMed
56.Effmann, EL, Whitman, S, Pexieder, T. Stereo microangiography in embryologic and teratologic investigation. Teratology 1986; 34: 103112.CrossRefGoogle Scholar
57.Janecek, P, Pexieder, T, Boillat, E, Waldvogel, H, Goel, Y, Diserens, B, Revaz, Ch, Pithon, G. Evaluation of 100 successful gonadotrophin stimulation cycles for IVF+ET. Gynecol 1986; 239: 196198.Google Scholar
58.Pexieder, T, Boillat, E, Janecek, P. Antisperm antibodies and in vitro fertilization. Arch Gynecol 1986; 239: 199203.Google Scholar
59.Pexieder, T. SEM in studies on abnormal cardiac development. Teratology 1988; 37: 289291.CrossRefGoogle ScholarPubMed
60.Vuillemin, M, Pexieder, T. Normal stages of cardiac organogenesis in the mouse: I. Development of the external shape of the heart. Amer J Anat 1989; 184: 101113.CrossRefGoogle ScholarPubMed
61.Vuillemin, M, Pexieder, T. Normal stages of cardiac organogenesis in the mouse: II. Development of the internal relief of the heart. Amer J Anat 1989; 184: 114128.CrossRefGoogle ScholarPubMed
62.Pexieder, T. Surveillance of potential teratogens. J Suisse de Pharmacie 1989; 20: 514516. [French]Google Scholar
63.Pexieder, T, Wenink, ACG, Anderson, RH. A suggested nomenclature for the developing heart. Int J Cardiol 1989; 25: 255264.CrossRefGoogle ScholarPubMed
64.Pexieder, T. Pathogenesis of neonatal heart failure: Truth and fiction. A Kardiol 1990; 79: 315323. [German]Google Scholar
65.Moscoso, G, Pexieder, T. Variations in microscopic anatomy and ultra-structure of human embryonic hearts subjected to three different modes of fixation. Path Res Pract 1990; 186: 768774.CrossRefGoogle Scholar
66.Pexieder, T, Bersinger, N, Boillat, E, Janecek, P. Serum levels of pregnancy-associated endometrial alpha 2-globulin. Human Reprod 1991; 6: 310311.CrossRefGoogle ScholarPubMed
67.Vuillemin, M, Pexieder, P. Pathogenesis of various forms of double outlet right ventricle in mouse fetal trisomy 13. Int J Cardiol 1991; 33: 281304.CrossRefGoogle ScholarPubMed
68.De Wals, P, Bloch, D, Calabro, A, Calzolari, E, Cornel, MC, Johnson, Z, Nevin, N, Pexieder, T, Stoll, C, Tenconi, R, Tilmont, P. Association between holoprosencephaly and exposure to topical retinoids: results of the Eurocat survey. Pediatr Perinat Epidemiol 1991; 5: 445447.CrossRefGoogle ScholarPubMed
69.Pexieder, T, Pflzenmaier Rousseil, M. Comments on target tissue specificity of retinoic-acid induced stress proteins and malformations in mice. Teratology 1992; 45: 121122.CrossRefGoogle ScholarPubMed
70.Taber, LA, Hu, N, Pexieder, T, Clark, EB, Keller, BB. Residual strain in the ventricle of the stage 16–24 chick embryo. Circ Res 1993; 72: 455462.CrossRefGoogle ScholarPubMed
71.Patterson, DF, Pexieder, T, Schwarz, WR, Navratil, T, Alaili, R. A single major-gene defect underlying cardiac conotruncal malformations interferes with myocardial growth during embryonic development: studies in the CTD line of Keeshond dogs. Am J Hum Genet 1993; 52: 388397.Google ScholarPubMed
72.Vuillemin, M, Pexieder, T, Yu-Man, MW, Thompson, RT. A two step alignement method for 3D computer aided recon struction based on fiducial markers and applied to mouse embryonic hearts. Eur J Morphol 1993; 30: 181193.Google Scholar
73.Pexieder, T. Studying experimental fetal cardiopathies. Teratology 1993; 47: 527528.CrossRefGoogle ScholarPubMed
74.Ninomiya, T, Vuillemin, M, Walter-Barakat, I, Winking, H, Pexieder, T, Droz, B. Mouse fetal trisomy 13 and hypotrophy of the spinal cord effect on calbindin-D28k and calretinin expressed by neurons of the spinal cord and dorsal root ganglia. Neuroscience 1993; 57: 11091120.CrossRefGoogle ScholarPubMed
75.Pexieder, T, Bloch, D. Congenital anomalies in Switzerland. Problems and solutions in data collection and their European integration experienced by Eurocat (Switzerland). Soz Praventivmed 1994; 34: 4346.CrossRefGoogle Scholar
76.Pexieder, T, Bloch, D. Stratification by size in the epidemiology of ventricular septal defects. Eurocat Newsletter 1994; 8: 12.Google Scholar
77.Lin, AE, Pexieder, T. Need for greater precision in reporting cardiovascular malformations. Amer J Med Genetics 1994; 51: 8485.CrossRefGoogle ScholarPubMed
78.Cornel, MC, Pexieder, T. Variation in prenatal cytogenetic diagnosis: policies in 13 European countries, 1989–1991. Prenat Diag 1994; 14: 337344.CrossRefGoogle ScholarPubMed
79.Stoll, Cl, Pexieder, T. Distribution of single organ malformations in European populations. Ann Genet 1995; 38: 3243.Google ScholarPubMed
80.Pexieder, T. The quantitative chart of cell death in the developing heart of the chick embryo between days 2 and 8 of incubation. Anat Anz 1971; 128: 295300. [German]Google Scholar
81.Pexieder, T. Observations on localized cell death during septation of the conotruncus in the chick embryo. Anat Anz 1972; 130: 279286. [German]Google Scholar
82.Pexieder, T. About the primary causes of cell death in conotruncus of the chick embryo. Anat Anz 1973; 134: 183187. [German]Google Scholar
83.Krstic, R, Pexieder, T. Electron microscopic observation on the highest point phase of cell death in bulbar cushions of the chick embryo. Anat Anz 1973; 134: 613618. [German]Google Scholar
84.Pexieder, T. The effect of cyclophosphamide on the area of physiologic cell death in the hearts of chick embryos. Anat Anz 1974; 136: 841847. [German]Google Scholar
85.Pexieder, T. The contribution of experimental embryology to the evaluation of teratogenic effect of new medications. Med Hyg 1975; 33: 10011005. [French]Google Scholar
86.Pexieder, T. Scanning electron microscopic observations on the surface of the bulbar cushions of the chick embryo. Verh Anat Ges 1976; 70: 747754. [German]Google Scholar
87.Pexieder, T. SEM observations of the embryonic endocardium under normal and experimental hemodynamic conditions. Bibl Anat 1977; 15: 531534.Google Scholar
88.Pexieder, T. Pathogenesis of cardiac malformations. Bull Fond Suisse Cardiol 1977; 8: 4248. [French]Google Scholar
89.Paschoud, N, Pexieder, T, Kazimierczak, J, Bucher, O. Contribution to the estimation of the number of renal corpuscules in the kidney of the rat. Verh Anat Ges 1978; 72: 577581. [German]Google Scholar
90.Pexieder, T. Compte rendu de: “T. Yamada, Control mechanisms in cell-type conversion in newt lens regeneration. S, Karger, Bale, 1977.” Schweiz Rundschau Med 1978; 67: 726. [French]Google Scholar
91.Pexieder, T. Scanning electron microscopy of the epithelium of the oviduct following surgical cauterization of the Fallopian tube. Rev Med Suisse Romande 1981; 101: 535541. [French]Google Scholar
92.Pexieder, T. The solution of two enigmas in the organogenesis of the heart. Bull Fond Suisse Cardiol 1982; 13: 3950. [French]Google Scholar
93.Pexieder, T. Prevention of congenital anomalies using epidemiologic studies and prenatal therapy. Med Hyg 1983; 41: 20172034. [French]Google Scholar
94.Pexieder, T. Final report on the Swiss participation in the collaborative study of COST. Registration of congenital anomalies and multiple births (1980–1983). Bull Fed Sante Publ 1984; 29: 438444. [French]Google Scholar
95.Pexieder, T. Exogenous teratogens. Gazette Medicale 1989; 3: 201208. [French]Google Scholar
96.Pexieder, T. Dealing with clusters. ENTIS Newsletter 1993; 3: 2631.Google Scholar
97.Pexieder, T. Do dental mercury fillings (amalgams) represent a risk for the fetus and newborn? ENTIS Newsletter 1995; 4: 1011.Google Scholar