Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-22T23:13:28.537Z Has data issue: false hasContentIssue false

The Senning operation for complete transposition: mid-term physiologic, electrophysiologic, and functional results

Published online by Cambridge University Press:  19 August 2008

Walter H. Merrill*
Affiliation:
Department of Cardiac and Thoracic Surgery and the Division of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee
James R. Stewart
Affiliation:
Department of Cardiac and Thoracic Surgery and the Division of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee
John W. Hammon Jr
Affiliation:
Department of Cardiac and Thoracic Surgery and the Division of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee
James A. Johns
Affiliation:
Department of Cardiac and Thoracic Surgery and the Division of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee
Harvey W. Bender Jr
Affiliation:
Department of Cardiac and Thoracic Surgery and the Division of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee
*
Dr. Walter H. Merrill Department of Cardiac and Thoracic Surgery, The Vanderbilt Clinic, Room 2973, Nashville, TN 37232U.S.A.

Summary

We report analysis of surgical results in 110 consecutive infants and children who underwent atrial repair of simple complete transposition using the Senning operation between February 1978 and May 1990. Mean age at operation was 5.4 months ± 6.1 (range 1 week to 4 years); 75 were less than 6 months old. There were 72 males and 38 females. Operative mortality rate was 5.5%, with one late death. Average follow-up is 48.1 months with 44 followed greater than 3 years, and 27 greater than 5 years. Postoperative cardiac catheterization was performed in 48 patients. Right ventricular ejection fraction averaged 0.52 ± 0.08 and was normal in 28 patients. Response of right ventricular ejection fraction to afrerload stress was abnormal in 12 of 14 patients tested. Right ventricular ejection fraction increased normally during exercise in 6 patients, but was abnormal in 15. Mild tricuspid regurgitation was noted in 12 patients. Mild obstruction of the superior caval vein was noted in 4 patients. Baffle leak requiring reoperation occurred in one patient. Fifty-seven of 90 patients are in sinus rhythm by latest electrocardiogram. Postoperative electrophysiologic studies were performed in 34 patients, and Holter monitoring in 25. Significant arrhythmia occurred in 26 patients: 6 patients required pacemakers for slow junctional rhythm or complete heart block; 20 additional patients have a junctional rhythm. Six patients have delayed sinus nodal recovery time. At last follow-up, 88 children (98%) are in New York Heart Association functional Class I, and 2 (2%) are in Class II. The Senning operation for compete transposition can be accomplished with a low operative and late mortality. Serious baffle complications requiring reoperation are rare. Surviving patients are clinically well, but arrhythmias and depressed right ventricular function may limit their long-term functional status.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Senning, A. Surgical correction of transposition of the great vessels. Surgery 1959; 45: 966980.Google ScholarPubMed
2.Quaegebeur, JM, Rohmer, J, Brom, AG, Tinkelenberg, J. Revival of the Senning operation for treatment of transposition of the great arteries. Thorax 1977; 32: 517524.CrossRefGoogle ScholarPubMed
3.Bender, HW, Graham, TP, Boucek, RJ, Walker, WE, Buerth, RG. Comparative operative results of the Senning and Mustard procedures for transposition of the great arteries. Circulation 1980; 62(Suppl I): I 197203.Google ScholarPubMed
4.Graham, TP, Burger, J, Bender, HW, Hammon, JW, Boucek, RJ, Appleton, S. Improved right ventricular function after intraatrial repair of transposition of the great arteries. Circulation 1985; 72(Suppl II): II 4551.Google ScholarPubMed
5.Bender, HW, Stewart, JR, Merrill, WH, Hammon, JW, Graham, TP. Ten years' experience with the Senning operation for transposition of the great arteries: physiological results and late follow-up. Ann Thorac Surg 1989; 47: 218223.CrossRefGoogle ScholarPubMed
6.Guidelines for data reporting and nomenclature for The Annals of Thoracic Surgery. Ann Thorac Surg 1988; 46: 260261.CrossRefGoogle Scholar
7.Borow, KM, Keane, JF, Castañeda, AR, Freed, MD. Systemic ventricular function in patients with tetralogy of Fallot, ventricular septal defect, and transposition of the great arteries repaired during infancy. Circulation 1981; 64: 878885.CrossRefGoogle ScholarPubMed
8.Trusler, GA, Williams, WG, Duncan, KF, Hesslein, PS, Benson, LN, Freedom, RM, Izukawa, T, Olley, PM. Results with the Mustard operation in simple transposition of the great arteries 1963–1985. Ann Surg 1987; 206: 251260.CrossRefGoogle ScholarPubMed
9.George, BL, Laks, H, Klitzner, TS, Friedman, WF, Williams, RG. Results of the Senning procedure in infants with simple and complex transposition of the great arteries. Am J Cardiol 1987; 59: 426430.CrossRefGoogle ScholarPubMed
10.Trusler, GA, Castañeda, AR, Rosenthal, A, Blackstone, EH, Kirklin, JW, and the Congenital Heart Surgeons Society Current results of management in transposition of the great arteries with special emphasis on patients with associated ventricular septal defect. J Am Coil Cardiol 1987; 10: 10611071.CrossRefGoogle ScholarPubMed
11.Waldhausen, JA, Pierce, WJ, Park, CD, Rashkind, WJ, Friedman, S. Physiologic correction of transposition of the great arteries: Indications for and results of operation in 32 patients. Circulation 1971; 43: 738747.CrossRefGoogle ScholarPubMed
12.Stark, J, deLeval, MR, Waterston, DJ, Graham, GR, Bonham-Carter, RE. Corrective surgery of transposition of the great arteries in the first year of life. J Thorac Cardiovasc Surg 1974; 67: 673681.CrossRefGoogle ScholarPubMed
13.Mahony, L, Turley, K, Ebert, P, Heyman, MA. Long-term results after atrial repair of transposition of the great arteries in early infancy. Circulation 1982; 66: 253258.CrossRefGoogle ScholarPubMed
14.Byrum, CJ, Bove, EL, Sondheimer, HM, Kavey, RW, Blackman, MS. Hemodynamic and electrophysioiogic results of the Senning procedure for transposition of the great arteries. Am J Cardiol 1986; 58: 138142.CrossRefGoogle ScholarPubMed
15.Weldon, CS, Hartmann, AF Jr, Kelly, JP. Current management of transposition of the great arteries: Immediate septostomy, occasional prostaglandin infusion and early Senning operations. Ann Thorac Surg 1983; 36: 1018.CrossRefGoogle ScholarPubMed
16.Ashrat, MH, Cotroneo, J, DiMarco, D, Subramanian, S. Fate of long-term survivors of Mustard procedure (inflow repair) for simple and complex transposition of the great arteries. Ann Thorac Surg 1986; 42: 385389.CrossRefGoogle Scholar
17.Duster, MC, Bink-Boelkens, MT, Wampler, D, Gillette, PC, McNamara, DG, Cooley, DA. Long-term follow-up of dysrhythmias following the Mustard procedure. Am Heart J 1985; 109: 13231326.CrossRefGoogle ScholarPubMed
18.Flinn, CJ, Wolff, AS, Dick, M, Campbell, RM, Borkat, G, Casta, A, Hordof, A, Hougen, TJ, Kavey, RE, Kugler, J, Liebman, J, Greenhouse, J, Hees, P. Cardiac rhythm after the Mustard operation for complete transposition of the great arteries. N Engl J Med 1984; 310: 16351638.CrossRefGoogle ScholarPubMed