Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-26T21:07:04.708Z Has data issue: false hasContentIssue false

The role of vasopressin in treating systemic inflammatory syndrome complicated by right ventricular failure

Published online by Cambridge University Press:  14 April 2005

Vladimiro L. Vida
Affiliation:
Pediatric Cardiac Surgery Unit, Unidad de Cirugía Cardiovascular de Guatemala, Guatemala, Central America
Ricardo Mack
Affiliation:
Intensive Cardiac Care Unit, Unidad de Cirugía Cardiovascular de Guatemala, Guatemala, Central America
Aldo R. Castañeda
Affiliation:
Pediatric Cardiac Surgery Unit, Unidad de Cirugía Cardiovascular de Guatemala, Guatemala, Central America

Abstract

Severe right ventricular failure complicated a postoperative systemic inflammatory response in a 33-year-old woman after surgical repair of congenital cardiac malformations. Volume loading, and high doses of catecholamines, failed to produce improvement, but treatment with vasopressin improved all haemodynamic parameters, and also allowed reduction of the other inotropes. After 10 days, the patient was discharged in stable condition from the intensive care unit.

Type
Brief Report
Copyright
2005 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Landry DW, Levin HR, Gallant EM, et al. Vasopressin pressor hypersensitivity in vasodilatory septic shock. Crit Care Med 1997; 25: 12791282.Google Scholar
Rosenzweig EB, Stare TJ, Chen JM, et al. Intravenous arginine-vasopressin in children with vasodilatory shock after cardiac surgery. Circulation 1999; 100: II182II186.Google Scholar
Liedel JL, Meadow W, Nachman J, Koogler T, Kahana MD. Use of vasopressin in refractory hypotension in children with vasodilatory shock: five cases and a review of the literature. Crit Care Med 2002; 3: 1518.Google Scholar
Holmes CL, Patel BM, Russell JA, Walley KR. Physiology of vasopressin relevant to management of septic shock. Chest 2001; 120: 9891002.Google Scholar
Tsuneyoshi I, Yamada H, Kakihana Y, et al. Hemodynamic and metabolic effects of low-dose vasopressin infusion in vasodilatory septic shock. Crit Care Med 2001; 29: 487493.Google Scholar
Garcia-Villalon AL, Garcia JL, Fernandez N, et al. Regional differences in the arterial response to vasopressin: role of endothelia nitric oxide. Br J Pharmacol 1996; 118: 18481854.Google Scholar
Evora PR, Pearson PJ, Schaff HV. Arginine vasopressine induced endothelium-dependent vasodilation of the pulmonary artery. V1-receptor-mediated production of nitric oxide. Chest 1993; 103: 12411245.Google Scholar
Leather HL, Segers P, Berends N, Vandermeersch E, Wouters PF. Effects of vasopressin on right ventricular function in an experimental model of acute pulmonary hypertension. Crit Care Med 2002; 30: 25482552.Google Scholar