Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-26T05:10:44.776Z Has data issue: false hasContentIssue false

Resolution of a therapy-resistant focal atrial tachycardia after omega-3 fatty acid supplementation

Published online by Cambridge University Press:  08 July 2019

Reiner Buchhorn*
Affiliation:
Department of Paediatrics, Caritas Krankenhaus, Bad Mergentheim, Germany
Christian Willaschek
Affiliation:
Department of Paediatrics, Caritas Krankenhaus, Bad Mergentheim, Germany
*
Author for correspondence: Prof. Dr. R. Buchhorn, Klinik für Kinder- und Jugendmedizin, Department of Paediatrics, Caritas Krankenhaus, Uhlandstraße 7, 97980, Bad Mergentheim, Germany. Tel: 49-7931-582301; Fax: 49-7931-582390. E-mail: [email protected]

Abstract

We report on a 14-year-old boy with focal atrial tachycardia. After failure of catheter ablation and medical therapy he received 2 g omega-3 fatty acid supplementation while waiting on repeat ablation. Focal atrial tachycardia disappeared 4 weeks later and antiarrhythmic therapy was terminated. We discuss the antiarrhythmic effect of omega 3-fatty acids on the autonomous nervous system based upon six 24-hour Holter electrocardiographs.

Type
Brief Report
Copyright
© Cambridge University Press 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Kang, KT, Etheridge, SP, Kantoch, MJ, et al. Current management of focal atrial tachycardia in children: a multicenter experience. Circ Arrhythm Electrophysiol 2014; 7: 664670.CrossRefGoogle ScholarPubMed
Medi, C, Kalman, JM, Haqqani, H, et al. Tachycardia-mediated cardiomyopathy secondary to focal atrial tachycardia: long-term outcome after catheter ablation. J Am Coll Cardiol 2009; 53: 17911797.10.1016/j.jacc.2009.02.014CrossRefGoogle ScholarPubMed
Siscovick, DS, Barringer, TA, Fretts, AM, et al. Omega-3 polyunsaturated fatty acid (fish oil) supplementation and the prevention of clinical cardiovascular disease: a science advisory from the American heart association. Circulation 2017; 135: e867e884.CrossRefGoogle ScholarPubMed
Oner, T, Ozdemir, R, Doksoz, O, et al. Cardiac function in children with premature ventricular contractions: the effect of omega-3 polyunsaturated fatty acid supplementation. Cardiol Young 2018; 28: 949954.CrossRefGoogle ScholarPubMed
Billman, GE. The effects of omega-3 polyunsaturated fatty acids on cardiac rhythm: a critical reassessment. Pharmacol Ther 2013; 140: 5380.CrossRefGoogle ScholarPubMed
Xiao, YF, Kang, JX, Morgan, JP, Leaf, A. Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytes. Proc Natl Acad Sci USA 1995; 92: 1100011004.CrossRefGoogle ScholarPubMed
Hallaq, H, Smith, TW, Leaf, A. Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids. Proc Natl Acad Sci USA 1992; 89: 17601764.CrossRefGoogle ScholarPubMed
La Rovere, MT, Christensen, JH. The autonomic nervous system and cardiovascular disease: role of n-3 PUFAs. Vascul Pharmacol 2015; 71: 110.CrossRefGoogle ScholarPubMed
Nodari, S, Triggiani, M, Campia, U, et al. Effects of n-3 polyunsaturated fatty acids on left ventricular function and functional capacity in patients with dilated cardiomyopathy. J Am Coll Cardiol 2011; 57: 870879.CrossRefGoogle ScholarPubMed
Buchhorn, R, Koenig, J, Jarczok, MN, et al. A case series on the potential effect of omega-3-fatty acid supplementation on 24-h heart rate variability and its circadian variation in children with attention deficit (hyperactivity) disorder. Atten Def Hyp Disord 2018; 10: 135139.10.1007/s12402-017-0240-yCrossRefGoogle ScholarPubMed
Buchhorn, R, Willaschek, C, Norozi, K. Improving heart rate variability in children with short stature by supplementing omega-3-fatty acids. J Food Nutr Popul Health 2017; 1: 16.Google Scholar
Baumann, C, Rakowski, U, Buchhorn, R. Omega-3 fatty acid supplementation improves heart rate variability in obese children. Int J Pediatr 2018; 2018: 5. Article ID 8789604. doi: 10.1155/2018/8789604CrossRefGoogle ScholarPubMed