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Primary involvement of the mitral and aortic valves in Takayasu's arteritis

Published online by Cambridge University Press:  19 August 2008

Harold S. Bernstein ,
Philip C. Ursell  and
David F. Teitel
Harold S. Bernstein*
Affiliation:
Department of Pediatrics (Division of Cardiology), University of California, San Francisco, CA, USA
Philip C. Ursell
Affiliation:
Department of Pediatrics (Division of Pathology), University of California, San Francisco, CA, USA
David F. Teitel
Affiliation:
Department of Pediatrics (Division of Cardiology), University of California, San Francisco, CA, USA
*
Harold S. Bernstein MD, PhD, University of California, San Francisco, Box 0632, San Fransisco, CA 94143. Fax: (415) 476 3112
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Abstract

A 3-year-old boy developed acute pulmonary edema following 6 months of recurrent fevers and thrombocytosis. Echocardiography demonstrated moderate-to-severe insufficiency of both mitral and aortic valves. Angiography and intravascular ultrasound were used to diagnose this unusual presentation of Takayasu's arteritis. To the best of our knowledge, this is the first histological demonstration of acute and chronic inflammatory changes in the mitral valve in these circumstances.

Keywords

Takayasu's arteritisvalvitisintravascular ultrasound
Type
Brief Reports
Information
Cardiology in the Young , Volume 7 , Issue 2 , April 1997 , pp. 228 - 231
Copyright
Copyright © Cambridge University Press 1997

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References

1.Lupi-Herrera, E, Sanchez-Torres, G, Marcushamer, J, Mispireta, J, Horwitz, S, Vela, JE. Takaysu's arteritis. clinical study of 107 cases. Am Heart J 1977;93(1):94–103.CrossRefGoogle Scholar
2.Rushing, L, Schoen, FJ, Hirsch, A, Lie, JT. Granulomatous aortic valvulitis associated with aortic insufficiency in Takayasu aortitis. Hum Pathol 1991;22(10): 1050–1053.CrossRefGoogle ScholarPubMed
3.Subramanyan, R, Joy, J, Balakrishnan, KG. Natural history of aortoarteritis (Takayasu's disease). Circulation 1989;80(3): 429–437.CrossRefGoogle ScholarPubMed
4.Emmanouilides, GC, Riemenschneider, TA, Allen, HD, Gutgesell, HP (eds). Moss, and Adams, Heart Disease in Infants, Children, and Adolescents. Williams and Wilkins, Baltimore, 1995, pp 1400–1452.Google Scholar
5.Payne, RM, Johnson, MC, Grant, JW, Strauss, AW. Toward a molecular understanding of congenital heart disease. Circulation 1995;91:(2):494–504.CrossRefGoogle Scholar
6.Scriver, C, Beaudet, A, Sly, W, Valle, D (eds). The Metabolic Basis of Inherited Disease. McGraw-Hill, New york, 1989, pp 1565–1587.Google Scholar
7.Bowyer, S, Mason, WH, McCurdy, DK, Takahashi, M. Polyarteritis nodosa (PAN) with coronary aneurysms: The Kawasaki-PAN controversy revisited. J Rheumatol 1994;21(8): 1585.Google ScholarPubMed
8.Gidding, SS, Shulman, ST, Ilbawi, M, Crussi, F, Duffy, CE. Mucocutaneous lymph node syndrome (Kawasaki disease): delayed aortic and mitral insufficiency secondary to active valvulitis. J Am Coll Cardiol 1986;7(4):894–897.CrossRefGoogle ScholarPubMed
9.Rowley, AH, Gonzalez-Crussi, F, Shulman, ST, Kawasaki diseas Rev Infect Dis 1988;10(1):1–15.CrossRefGoogle Scholar
10.Rein, AJ, Preminger, TJ, Perry, SB, Lock, JE, Sanders, SP. Generalized arteriopathy in Williams syndrome: an intravascular ultrasound study. J Am Coll Cardiol 1993;21(7):1727–1730.CrossRefGoogle ScholarPubMed