Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-23T04:49:25.182Z Has data issue: false hasContentIssue false
  • English
  • Français

Myocardial Infarction in a newborn from a diabetic mother

Published online by Cambridge University Press:  02 June 2010

Julie Abbal ,
Soizic Paranon ,
Gilles Brierre ,
Yves Dulac ,
Charlotte Casper  and
Philippe Acar
Julie Abbal
Affiliation:
Pediatric Cardiology, Children Hospital Toulouse, France
Soizic Paranon
Affiliation:
Pediatric Cardiology, Children Hospital Toulouse, France
Gilles Brierre
Affiliation:
Pediatric Cardiology, Children Hospital Toulouse, France
Yves Dulac
Affiliation:
Pediatric Cardiology, Children Hospital Toulouse, France
Charlotte Casper
Affiliation:
Neonatology, Children Hospital Toulouse, France
Philippe Acar*
Affiliation:
Pediatric Cardiology, Children Hospital Toulouse, France
*
Correspondence to: Pr Ph Acar, Pediatric Cardiology, Children’s Hospital, 330 Avenue de Grande Bretagne, 31026 Toulouse Cedex 3, France. Tel: 33 5 34 55 87 34; Fax: 33 5 34 86 63; E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

We extracted L., the newborn of a diabetic mother, for antenatal diagnostic of myocardial hypertrophy and anomaly of foetal heart rate. Post-natal echocardiography showed severe septal myocardial hypertrophy with latero-basal myocardial akinesia. We did not observe a Doppler gradient through the left ventricular outflow. Selective coronary angiography showed an occlusion of the circumflex artery. Myocardial hypertrophy is a classic complication in newborns of diabetic mothers. The mother’s diabetes and neonatal infarction remain an exceptional association. We discuss a different hypothesis to explain coronary occlusion and how myocardial infarction avoided septal obstruction.

Keywords

Myocardial hypertrophymyocardial ischaemiamaternal diabetescoronary occlusion
Type
Brief Reports
Information
Cardiology in the Young , Volume 20 , Issue 4 , August 2010 , pp. 451 - 454
Copyright
Copyright © Cambridge University Press 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Abu-Sulaiman, RM, Subaih, B. Congenital heart disease in infants of diabetic mothers: echocardiographic study. Pediatr Cardiol 2004; 25: 137–140.CrossRefGoogle ScholarPubMed
2. Ullmo, S, Vial, Y, Di Bernardo, S, et al. . Pathologic ventricular hypertrophy in the offspring of diabetic mothers: a retrospective study. Eur Heart J 2007; 28: 1319–1325.Google Scholar
3. Schwartz, R, Teramo, KA. Effects of diabetic pregnancy on the fetus and newborn. Sem Perinat 2000; 4: 120–135.CrossRefGoogle Scholar
4. Sardesai, MG, Gray, AA, McGrath, MM, Ford, SE. Fatal hypertrophic cardiomyopathy in the fetus of a woman with diabetes. Obstet Gynecol 2001; 98: 925–927.Google Scholar
5. Prefumo, F, Celentano, C, Presti, F, De Biasio, P, Venturini, PL. Acute presentation of fetal hypertrophic cardiomyopathy in a type 1 diabetic pregnancy. Diabetes Care 2005; 28: 2084.CrossRefGoogle Scholar
6. Gault, MH, Usher, R. Coronary thrombosis with myocardial infarction in a newborn infant. Clinical, electrocardiographic and post-mortem findings. N Engl J Med 1960; 25: 379–382.CrossRefGoogle Scholar
7. Ferns, S, Khan, M, Firmin, R, Peek, G, Bu’Lock, F. Neonatal myocardial infarction and the role of extracorporal membrane oxygenation. Arch Dis Child Fetal Neonatal 2009; 94: F54–F57.CrossRefGoogle Scholar
8. Bernstein, D, Finkbeiner, WE, Soifer, S, Teitel, D. Perinatal myocardial infarction: a case report and review of the literature. Pediatr Cardiol 1986; 6: 313–317.Google ScholarPubMed
9. Lucas, VW Jr, Burchfield, DJ, Donnelly, WH Jr. Multiple coronary thromboemboli and myocardial infarction in a newborn infant. J Perinatol 1994; 14: 145–149.Google Scholar
10. Murugan, SJ, Gnanapragasam, J, Vettukattil, J. Acute myocardial infarction in the neonatal period. Cardiol Young 2002; 12: 411–413.CrossRefGoogle ScholarPubMed
11. Bulbul, ZR, Rosenthal, DN, Kleinman, CS. Myocardial infarction in the perinatal period secondary to maternal cocaine abuse. A case report and literature review. Arch Pediatr Adolesc Med 1994; 148: 1092–1096.Google Scholar
12. Dimitriu, AG, Scumpu, G, Brumariu, O, et al. . Myocardial infarct in children. The anatomicoclinical aspects. Rev Med Chir Soc Med Nat Iasi 1993; 97: 401–404.Google Scholar
13. Kilbride, H, Way, GL, Merenstein, GB, Winfield, JM. Myocardial infarction in the neonate with normal heart and coronary arteries. Am J Dis Child 1980; 134: 759–762.Google ScholarPubMed
14. Iannone, LA, Duritz, G, McCarthy, RJ. Myocardial infarction in the newborn: a case report complicated by cardiogenic shock and associated with normal coronary arteries. Am Heart J 1975; 89: 232–235.Google Scholar