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Mitral annular disjunction versus myocardial Ischemia in coronary artery anomalies

Published online by Cambridge University Press:  02 April 2025

Vincent Bui Open the ORCID record for Vincent Bui [Opens in a new window] ,
Silvana Molossi Open the ORCID record for Silvana Molossi [Opens in a new window] ,
Lindsay F. Eilers ,
Shagun Sachdeva  and
Tam T. Doan Open the ORCID record for Tam T. Doan [Opens in a new window]
Vincent Bui*
Affiliation:
The University of the Incarnate Word School of Osteopathic Medicine, San Antonio, TX, USA
Silvana Molossi
Affiliation:
Coronary Artery Anomalies Program, Division of Cardiology, Texas Children’s Hospital, Houston, TX, USA Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Lindsay F. Eilers
Affiliation:
Coronary Artery Anomalies Program, Division of Cardiology, Texas Children’s Hospital, Houston, TX, USA Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Shagun Sachdeva
Affiliation:
Coronary Artery Anomalies Program, Division of Cardiology, Texas Children’s Hospital, Houston, TX, USA Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Tam T. Doan
Affiliation:
Coronary Artery Anomalies Program, Division of Cardiology, Texas Children’s Hospital, Houston, TX, USA Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
*
Corresponding author: Vincent Bui; Email: [email protected]
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Abstract

Both mitral annular disjunction and coronary artery anomalies are associated with ventricular arrhythmia, though data on their co-occurrence are limited. We herein present two patients with anomalous aortic origin of a coronary artery and mitral annular disjunction who had ventricular arrhythmia. Mitral annular disjunction should be considered as a potential cause of ventricular arrhythmia when stress tests rule out ischaemia.

Keywords

Coronary artery anomalyMitral annular disjunctionSudden cardiac deathVentricular arrhythmia
Type
Brief Report
Information
Cardiology in the Young , First View , pp. 1 - 3
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Copyright
© The Author(s), 2025. Published by Cambridge University Press

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References

Doan, TT, Zea-Vera, R, Agrawal, H, et al. Myocardial ischemia in children with anomalous aortic origin of a coronary artery with intraseptal course. Circ Cardiovasc Interv. 2020; 13 ( 3 ): e008375.CrossRefGoogle ScholarPubMed
Doan, TT, Sachdeva, S, Bonilla-Ramirez, C, et al. Ischemia in anomalous aortic origin of a right coronary artery: large pediatric cohort medium-term outcomes. Circ Cardiovasc Interv 2023; 16 ( 4 ): e012631.CrossRefGoogle ScholarPubMed
Ezzeddine, FM, Siontis, KC, Giudicessi, J, et al. Substrate characterization and outcomes of catheter ablation of ventricular arrhythmias in patients with mitral annular disjunction. Circ Arrhythm Electrophysiol 2022; 15 ( 9 ): e011088.CrossRefGoogle ScholarPubMed
Doan, T, Morris, S. Mitral annular disjunction and “Pseudo” mitral annular disjunction in mitral valve prolapse. J Am Coll Cardiol Case Rep 2024; 29:(16). https://doi.org/10.1016/j.jaccas.2024.102436.Google ScholarPubMed
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