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Mid-term follow-up study of neonatal isolated aberrant right subclavian artery

Published online by Cambridge University Press:  28 June 2018

Sheng-Ling Jan*
Affiliation:
Division of Pediatric Cardiology, Children’s Medical Center, Taichung Veterans General Hospital, Taichung, Taiwan Department of Pediatrics, School of Medicine, National Yang-Ming University, Taipei, Taiwan Department of Pediatrics, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
Ming-Chih Lin
Affiliation:
Division of Pediatric Cardiology, Children’s Medical Center, Taichung Veterans General Hospital, Taichung, Taiwan Department of Pediatrics, School of Medicine, National Yang-Ming University, Taipei, Taiwan
Sheng-Ching Chan
Affiliation:
Department of Nursing, Ta-Jen University, Pingtung County, Taiwan
*
Author for correspondence: S.-L. Jan, MD, PhD, Division of Pediatric Cardiology, Children’s Medical Center, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect. 4, Taichung 40705, Taiwan. Tel: +886 4 23741259; Fax: +886 4 23741359; E-mail: [email protected]

Abstract

Background

Aberrant right subclavian artery is the most common congenital aortic arch anomaly. There are a few reports concerning the clinical manifestations and follow-up of this CHD detected by echocardiographic screening.

Methods

A total of 1737 full-term neonates, with a male-to-female ratio of 900:837, received echocardiographic screening. Neonates with or without isolated aberrant right subclavian artery were studied during infancy.

Results

Among the 1737 cases, a total of 15 (0.86%) female-predominant neonates, with a male-to-female ratio of 6:9, had isolated aberrant right subclavian artery. They were compared with 20 age- and gender-matched normal neonates. There were no significant differences in maternal age, gestational age, or para gravity between the two groups, except for birth size (birth length- and weight-for-age percentiles, p = 0.006 and 0.045, respectively), which was smaller in the aberrant right subclavian artery group. Although there were no significant differences in developmental history, gastrointestinal, or respiratory symptoms, neonates with aberrant right subclavian artery had a higher incidence of mild developmental delay and feeding difficulty than normal infants (21 versus 0%, p = 0.061; 36 versus 20%, p = 0.264, respectively). The growth rates of body length and weight during infancy were not significantly different between the two groups.

Conclusions

Echocardiography can be applied as a first-line investigation in the diagnostic work-up for aberrant right subclavian artery. Neonates with aberrant right subclavian artery had a smaller size at birth, although growth rates were not significantly different from those of normal infants. This study does not support an active surgical policy for asymptomatic infants with isolated aberrant right subclavian artery. A larger study and longer follow-up of affected infants is recommended.

Type
Original Article
Copyright
© Cambridge University Press 2018 

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Footnotes

Cite this article: Jan S.-L., Lin M.-C., Chan S.-C. (2018) Mid-term follow-up study of neonatal isolated aberrant right subclavian artery. Cardiology in the Young28: 1024–1030. doi: 10.1017/S1047951118000872

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