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‘Malignant’ congenital cardiovascular disease in twins with William's syndrome

Published online by Cambridge University Press:  19 August 2008

Andrew M. Davis
Affiliation:
From the Departments of CardiologyRoyal Children's Hospital, Melbourne
John Burn
Affiliation:
the Division of Human Genetics, University of Newcastle-Upon-Tyne
Tom R. Karl*
Affiliation:
From the Departments of Cardiac Surgery, Melbourne
*
Department of Cardiac Surgery, Royal Children's Hospital, Melbourne.

Summary

Twins of like sex and concordant for William's syndrome are presented. The first twin presented late with aortic arch atresia and has subsequently developed hypertension associated with renal arterial stenosis. The second twin died with myocardial ischemia late after surgery for supravalvar aortic and pulmonary stenosis.

Type
Brief Reports
Copyright
Copyright © Cambridge University Press 1993

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References

1.Burn, J.. William's syndrome. J Med Genet 1986; 23:389395.CrossRefGoogle Scholar
2.Page, HLVogel, JHKPryor, RBlount, SG. Unusual observa tions in supravalvar aortic stenosis. Circulation 1965; 32(Suppl I): I 166, [Abstract]Google Scholar
3.Wiltse, HEGoldbloom, RBAntia, AUOttesen, OERowe, RDCooke, RE. Infantile hypercalcaemia syndrome in twins. N EnglJ Med 1966; 275: 11571160.CrossRefGoogle ScholarPubMed
4.Cortada, XTaysi, KHartmann, AF. Familial William's syn drome. Clin Genet 1980; 18: 173176.CrossRefGoogle Scholar
5.Preus, M. Differential diagnosis of the William's and the Noonan's syndrome. Clin Genet 1984; 25: 429434.CrossRefGoogle Scholar
6.Murphy, MBGreenberg, FWilson, GHughes, MDiLiberti, JWilliams syndrome in twins. Am J Med Genet 1990; 6(Suppl): 9799.Google ScholarPubMed
7.Tehurne, PEBuchino, JJRees, AH. Myocardial infarction associated with with supravalvular aortic stenosis. J Pediatr 1985; 106: 251254.CrossRefGoogle Scholar
8.Rashkind, WJ, Golinko, RArcasoy, M. Cardiac findings in ideopathic hypercalcaemia of infancy. J Pediatr 1961; 58:464469.CrossRefGoogle Scholar
9.Conway, EENoonan, JMarion, RWSteeg, CN. Myocardial infarction leading to sudden death in the William's syndrome. J Pediatr 1990; 117: 593595.CrossRefGoogle Scholar
10.Maisuls, HAlday, LEThuer, O. Cardiovascular findings its the Williams-Beuren syndrome. Am Hearrj 1987; 114: 897899.CrossRefGoogle ScholarPubMed