Hostname: page-component-cd9895bd7-gxg78 Total loading time: 0 Render date: 2024-12-27T04:23:48.717Z Has data issue: false hasContentIssue false
  • English
  • Français

Global Leadership in Paediatric and Congenital Cardiac Care: “Following the ‘Golden Rule’ in multicentre collaborations – an interview with Jane W. Newburger, MD”

Part of: CTY Global Leadership in Paediatric and Congenital Cardiac Care

Published online by Cambridge University Press:  06 August 2020

Justin T. Tretter  and
Jeffrey P. Jacobs
Justin T. Tretter*
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA Department of Pediatrics, University of Cincinnati College of Medicine,Cincinnati, OH, USA
Jeffrey P. Jacobs
Affiliation:
Congenital Heart Center, UF Health Shands Children’s Hospital, Gainesville, FL, USA Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Florida,Gainesville, FL, USA Cardiology in the Young, Cambridge, UK
*
Author for correspondence: Justin T. Tretter, M.D., The Heart Institute, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH45229, USA. Tel: 513-636-4432; Fax: 513-636-3952. E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Dr. Jane Newburger is the focus of our first in a planned series of interviews in Cardiology in the Young entitled, “Global Leadership in Paediatric and Congenital Cardiac Care”. Dr. Newburger was born in Manhattan, New York, United States of America. She was raised in the Bronx for her first six years of life, at which point her family moved to Yonkers, New York, where she spent the rest of her childhood. She then attended Bryn Mawr College where she majored in psychology. Dr. Newburger subsequently attended Harvard Medical School, graduating in 1974. She did her internship and residency in paediatrics at Boston Children’s Hospital in 1974–1976, followed by her fellowship at Boston Children’s Hospital in 1976–1979. She received her Masters in Public Health at the Harvard School of Public Health in 1980.

Dr. Newburger has spent her entire career as a paediatric cardiologist at Boston Children’s Hospital and Harvard Medical School, where she was appointed a Professor of Pediatrics in 1999 and has held the position as Commonwealth Professor of Pediatrics since 2008. She has established herself as a leading clinical scientist within the field of paediatric cardiology, with expertise in leadership of multicentre and multidisciplinary research, including the building of collaborative groups. She has been continuously funded by the National Institute of Health since 1982, and amongst other areas has led the field in the areas of neurodevelopmental outcomes in congenital heart disease, improved methods of vital organ support, and management of Kawasaki disease. This article presents our interview with Dr. Newburger, an interview that covers her path towards becoming a clinical scientist, her interests spanning four decades of hard work, and her strategies to design and lead successful multicentre studies.

Keywords

cardiologycongenital heart diseaseinterviewKawasaki diseasemulticentre collaborationneurodevelopmental outcomes
Type
Interview
Information
Cardiology in the Young , Volume 30 , Issue 9 , September 2020 , pp. 1221 - 1225
Copyright
© The Author(s), 2020. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Newburger, JW, Rosenthal, A, Williams, RG, Fellows, K, Miettinen, OS.Noninvasive tests in the initial evaluation of heart murmurs in children. N Engl J Med 1983; 308: 61–64.CrossRefGoogle ScholarPubMed
Newburger, JW, Silbert, AR, Buckley, LP, Fyler, DC.Cognitive function and age at repair of transposition of the great arteries in children. N Engl J Med 1984; 310: 1495–1499.CrossRefGoogle ScholarPubMed
Newburger, JW, Jonas, RA, Wernovsky, G, et al. A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery. N Engl J Med 1993; 329: 1057–1064.CrossRefGoogle ScholarPubMed
Gruber, EM, Jonas, RA, Newburger, JW, Zurakowski, D, Hansen, DD, Laussen, PC.The effect of hematocrit on cerebral blood flow velocity in neonates and infants undergoing deep hypothermic cardiopulmonary bypass. Anesth Analg 1999; 89: 322–327.Google ScholarPubMed
Newburger, JW, Jonas, RA, Soul, J, et al. Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery. J Thorac Cardiovasc Surg 2008; 135: 347–354, 354.e1–4.CrossRefGoogle ScholarPubMed
Jonas, RA, Bellinger, DC, Rappaport, LA, et al. Relation of pH strategy and developmental outcome after hypothermic circulatory arrest. J Thorac Cardiovasc Surg 1993; 106: 362–368.CrossRefGoogle ScholarPubMed
du Plessis, AJ, Jonas, RA, Wypij, D, et al. Perioperative effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants. J Thorac Cardiovasc Surg 1997; 114: 991–1000; discussion 1000–1001.CrossRefGoogle ScholarPubMed
Bellinger, DC, Wypij, D, du Plessis, AJ, et al. Developmental and neurologic effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants. J Thorac Cardiovasc Surg 2001; 121: 374–383.CrossRefGoogle ScholarPubMed
Bellinger, DC, Wypij, D, duPlessis, AJ, et al. Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: The Boston Circulatory Arrest Trial. J Thorac Cardiovasc Surg 2003; 126: 1385–1396. doi: 10.1016/s0022-5223(03)00711-6CrossRefGoogle ScholarPubMed
Bellinger, DC, Newburger, JW, Wypij, D, Kuban, KC, duPlesssis, AJ, Rappaport, LA.Behaviour at eight years in children with surgically corrected transposition: The Boston Circulatory Arrest Trial. Cardiol Young 2009; 19: 86–97. doi: 10.1017/S1047951108003454CrossRefGoogle ScholarPubMed
Newburger, JW, Sleeper, LA, Bellinger, DC, et al. Early developmental outcome in children with hypoplastic left heart syndrome and related anomalies: the single ventricle reconstruction trial. Circulation 2012; 125: 2081–2091.CrossRefGoogle ScholarPubMed
Newburger, JW, Sleeper, LA, Frommelt, PC, et al. Transplantation-free survival and interventions at 3 years in the single ventricle reconstruction trial. Circulation 2014; 129: 2013–2020.CrossRefGoogle ScholarPubMed
Burch, PT, Gerstenberger, E, Ravishankar, C, et al. Longitudinal assessment of growth in hypoplastic left heart syndrome: results from the single ventricle reconstruction trial. J Am Heart Assoc 2014; 3: e000079.CrossRefGoogle ScholarPubMed
Frommelt, PC, Gerstenberger, E, Cnota, JF, et al. Impact of initial shunt type on cardiac size and function in children with single right ventricle anomalies before the Fontan procedure: the single ventricle reconstruction extension trial. J Am Coll Cardiol 2014; 64: 2026–2035.CrossRefGoogle ScholarPubMed
Johnson, JT, Sleeper, LA, Chen, S, et al. Associations between day of admission and day of surgery on outcome and resource utilization in infants with hypoplastic left heart syndrome who underwent stage I palliation (from the single ventricle reconstruction trial). Am J Cardiol 2015; 116: 1263–1269.CrossRefGoogle Scholar
Ravishankar, C, Gerstenberger, E, Sleeper, LA, et al. Factors affecting Fontan length of stay: Results from the Single Ventricle Reconstruction trial. J Thorac Cardiovasc Surg 2016; 151: 669–675.e1.CrossRefGoogle ScholarPubMed
Bucholz, EM, Sleeper, LA, Newburger, JW.Neighborhood socioeconomic status and outcomes following the Norwood procedure: an analysis of the pediatric heart network single ventricle reconstruction trial public data set. J Am Heart Assoc 2018; 7.CrossRefGoogle Scholar
Newburger, JW, Sleeper, LA, Gaynor, JW, et al. Transplant-free survival and interventions at 6 years in the SVR trial. Circulation 2018; 137: 2246–2253.CrossRefGoogle ScholarPubMed
Mahle, WT, Hu, C, Trachtenberg, F, et al. Heart failure after the Norwood procedure: an analysis of the single ventricle reconstruction trial. J Heart Lung Transplant 2018; 37: 879–885.CrossRefGoogle ScholarPubMed
Newburger, JW, Takahashi, M, Burns, JC, et al. The treatment of Kawasaki syndrome with intravenous gamma globulin. N Engl J Med 1986; 315: 341–347.CrossRefGoogle ScholarPubMed
Furusho, K, Sato, K, Soeda, T, et al. High-dose intravenous gammaglobulin for Kawasaki disease. Lancet 1983; 2: 1359.CrossRefGoogle ScholarPubMed
Furusho, K, Kamiya, T, Nakano, H, et al. High-dose intravenous gammaglobulin for Kawasaki disease. Lancet 1984; 2: 1055–1058.CrossRefGoogle ScholarPubMed
Newburger, JW, Fyler, DC. The paediatric cardiology hall of fame – Alexander Sandor Nadas: November 12, 1913–May 15, 2000. Cardiol Young 2004; 14(1): 75–82. doi: 10.1017/s1047951104001131CrossRefGoogle Scholar
Newburger, JW, Fyler, J, Colan, SD. The paediatric cardiology hall of fame – Donald Charles Fyler: 1924–2011. Cardiol Young 2011; 21(5): 485–489. doi: 10.1017/s1047951111001089CrossRefGoogle Scholar